Carbon Oxygen Demand Standards
Apexbio Technology LLC Tioconazole 65899-73-2 10g
Tioconazole (65899-73-2) is a small-molecule inhibitor targeting the fungal cytochrome P450-dependent enzyme lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane stability and cellular integrity Tioconazole exerts its biological activity primarily through interference with ergosterol biosynthesis within fungal cell membranes In in vitro studies Tioconazole demonstrates inhibitory activity with MIC50 values below 3 12 mg/L for dermatophyte strains and below 9 mg/L for yeast species Based on these pharmacological properties Tioconazole holds research potential in the study of antifungal mechanisms and in vitro antifungal screening assays
Apexbio Technology LLC PTP Inhibitor I 2491-38-5 10g
PTP Inhibitor I (CAS 2491-38-5) is a small molecule inhibitor targeting protein tyrosine phosphatases (PTPs) specifically SHP-1 and PTP1B with inhibition constants (KI) of 43 M and 42 M respectively As an -bromoacetophenone derivative it acts as a neutral phosphotyrosine mimetic covalently modifying the active site cysteine of PTPs Structure-activity studies indicate that modifications to the phenyl ring moderately affect potency while para-substituted peptidyl groups can enhance both potency and selectivity PTP Inhibitor I is utilized in vitro for mechanistic studies of PTP function related to diabetes neurodegenerative disorders immune regulation and pathogen virulence Animal and clinical data are not available
Apexbio Technology LLC Prilocaine hydrochloride 1786-81-8 10g
Prilocaine hydrochloride (CAS 1786-81-8) is a local anesthetic belonging to the amino amide class It functions by reversibly inhibiting voltage-gated sodium channels on neuronal cell membranes thereby blocking the initiation and propagation of nerve impulses This property makes it suitable for investigating neuronal excitability pain signaling and ion channel pharmacology in various preclinical models Prilocaine hydrochloride is commonly employed in studies requiring local anesthesia and serves as a reference compound for benchmarking novel anesthetic agents in research settings
Hach Company COD Standard Solution, 1000 mg/L as COD (NIST), 200 mL
For accuracy checks in Chemical Oxygen Demand determinations. 200 mL bottle
Apexbio Technology LLC L-Acetylcarnitine (hydrochloride) 5080-50-2 10g
L-Acetylcarnitine (hydrochloride) (CAS 5080-50-2) an acetylated derivative of L-carnitine facilitates the mitochondrial uptake of acetyl-CoA supporting fatty acid oxidation and energy metabolism It enhances acetylcholine synthesis and contributes to membrane phospholipid and protein production In vitro L-acetylcarnitine reduces SKOV-3 ovarian cancer cell proliferation at higher concentrations without affecting CA-125 or nerve growth factor receptor expression In vivo studies demonstrate its rapid and sustained antidepressant-like activity in rodent models linked to epigenetic upregulation of mGlu2 (Grm2) receptors L-acetylcarnitine is utilized in research focusing on metabolism neurobiology and psychiatric disorders
Apexbio Technology LLC Tamoxifen Citrate 54965-24-1 10g
Tamoxifen Citrate (CAS 54965-24-1) is a small-molecule antagonist targeting estrogen receptors (ER) It is designed to competitively bind ER thereby modulating estrogen-mediated signal transduction Tamoxifen Citrate exerts its biological activity primarily by inhibiting the transcriptional activity of estrogen-responsive genes leading to reduced synthesis of factors related to cell growth and angiogenesis In in vitro studies Tamoxifen Citrate demonstrates inhibition of cell proliferation with reported IC50 values typically ranging from 3 to 7 M depending on cell line and experimental conditions Based on these pharmacological properties Tamoxifen Citrate holds research potential in studies of estrogen receptor-dependent signaling pathways and anti-tumor strategies particularly in breast cancer models
Apexbio Technology LLC Bisphenol B 77-40-7 10g
Bisphenol B (CAS 77-40-7) is a synthetic bisphenol compound structurally analogous to bisphenol A It functions as an endocrine-disrupting chemical by binding to and activating estrogen receptors thereby mimicking the action of endogenous estrogens and potentially altering hormonal signaling pathways Owing to these properties Bisphenol B is widely utilized in toxicological and biomedical research to investigate endocrine disruption reproductive toxicity and possible health risks associated with environmental exposure to bisphenol analogues Its study supports risk assessment and informs regulatory evaluations of bisphenol-related substances
Apexbio Technology LLC Solutol HS-15 61909-81-7 10g
Solutol HS-15 (CAS 61909-81-7) is a nonionic surfactant composed of polyethylene glycol esters of 12-hydroxystearic acid Functioning by enhancing solubilization and membrane permeability Solutol HS-15 increases the aqueous solubility and bioavailability of poorly water-soluble compounds It facilitates transmembrane transport and promotes drug absorption by improving drug stability and modulating drug release profiles Due to its favorable biocompatibility and low cytotoxicity Solutol HS-15 is widely utilized as a pharmaceutical excipient in formulation research particularly for the delivery and controlled release of hydrophobic therapeutics
Apexbio Technology LLC Diclofenac Potassium 15307-81-0 10g
Diclofenac potassium (CAS 15307-81-0) is a synthetic small molecule belonging to the nonsteroidal anti-inflammatory drug (NSAID) class It functions primarily by inhibiting cyclooxygenase (COX) enzymes thereby reducing the synthesis of prostaglandins involved in inflammation and nociception Through this mechanism diclofenac potassium attenuates inflammatory responses and mediates analgesic effects It is frequently utilized in biomedical research to study inflammatory pathways investigate mechanisms of pain modulation and evaluate anti-inflammatory interventions in cellular and preclinical models
Apexbio Technology LLC Amoxicillin 26787-78-0 10g
Amoxicillin (26787-78-0) is a small-molecule inhibitor targeting bacterial penicillin-binding proteins (PBPs) It is designed to disrupt bacterial cell wall biosynthesis thereby impairing peptidoglycan cross-linking and compromising cell wall integrity Amoxicillin exerts its biological activity primarily through inhibition of PBPs interfering with the processes critical to bacterial cell wall formation In in vitro studies Amoxicillin demonstrates inhibitory activity with IC50 values ranging from 0 1 to 5 g/mL depending on experimental conditions and organism susceptibility Based on these pharmacological properties Amoxicillin holds research potential in studies of bacterial infection mechanisms antimicrobial responses and resistance development
Apexbio Technology LLC (-)-Tetramisole 16595-80-5 10g
(-)-Tetramisole is an immunomodulatory agent that stimulates nicotinic acetylcholine receptors leading to the activation of T-lymphocytes macrophages and phagocytic cells to enhance cell-mediated immune responses (-)-Tetramisole exerts its biological activity primarily through activation of nicotinic acetylcholine receptors Additionally it is utilized in the investigation of epigenetic regulation pathways involving lysine-specific demethylase 1 (LSD1) serving as a research tool to study chromatin modulation mechanisms and gene expression control Based on these pharmacological properties (-)-Tetramisole holds research potential in immunological signaling studies and tumor biology