Acetylides
Medchemexpress LLC Bis-propargyl-PEG6 100mg | 400775-35-1 | 358.43 g·mol⁻¹ | C18H30O7 | 100 MG
Bis-propargyl-PEG6 is a polyethylene glycol (PEG) linker bearing two terminal propargyl (alkyne) groups separated by a six-unit PEG spacer. It supplies clickable alkyne handles for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and is used to build bifunctional molecules such as PROTACs, polymer-linked multimers, and other bioconjugates. Molecular formula C18H30O7; MW 358.43 g·mol⁻1; CAS 400775-35-1.
- Provides two terminal alkyne handles for click chemistry.
- Six-unit PEG spacer improves aqueous solubility and flexibility.
- Well suited for PROTAC linker construction and bioconjugation.
- Compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Typically supplied as a 100 MG package; store at -20 °C for stability.
Matrix Scientific 2-Propynylamine, 2450-71-7, MFCD00008198, 25g
Molecular Formula C3H5N, Purity 98%, Molecular Weight 55.08, Boiling Point 83
(C)C#C | 100g | 449742390](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000165834.jpg-250.jpg)
eMolecules 1066-54-2 | TRIMETHYLSILYLACETYLENE | AstaTech | MFCD00008569 | 98.220 | C5H10Si | 97.000 | C[Si](C)(C)C#C | 100g | 449742390
TRIMETHYLSILYLACETYLENE | AstaTech | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 97.000 | C[Si](C)(C)C#C | 100g | 449742390
![eMolecules 2007921-20-0 | 3-aminobicyclo[1.1.1]pentan-1-ol hydrochloride | Pharmablock | MFCD28501812 | 135.590 | C5H10ClNO | 97.000 | Cl.NC12CC(O)(C1)C2 | 2.5g | 686938324](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000170617.jpg-250.jpg)
eMolecules 2007921-20-0 | 3-aminobicyclo[1.1.1]pentan-1-ol hydrochloride | Pharmablock | MFCD28501812 | 135.590 | C5H10ClNO | 97.000 | Cl.NC12CC(O)(C1)C2 | 2.5g | 686938324
3-aminobicyclo[1.1.1]pentan-1-ol hydrochloride | Pharmablock | 2007921-20-0 | MFCD28501812 | 135.590 | C5H10ClNO | 97.000 | Cl.NC12CC(O)(C1)C2 | 2.5g | 686938324
![eMolecules 2197502-05-7 | 3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride | Combi-Blocks, Inc. | MFCD30489933 | 149.620 | C6H12ClNO | 97.000 | Cl.COC12CC(N)(C1)C2 | 5g | 818524322](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000162428.jpg-250.jpg)
eMolecules 2197502-05-7 | 3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride | Combi-Blocks, Inc. | MFCD30489933 | 149.620 | C6H12ClNO | 97.000 | Cl.COC12CC(N)(C1)C2 | 5g | 818524322
3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride | Combi-Blocks, Inc. | 2197502-05-7 | MFCD30489933 | 149.620 | C6H12ClNO | 97.000 | Cl.COC12CC(N)(C1)C2 | 5g | 818524322
Medchemexpress LLC Bis-propargyl-PEG8 10mg | 1092554-87-4 | 10 MG
Bis-propargyl-PEG8 is a PEG8-based bifunctional linker bearing terminal propargyl (alkyne) groups, used as a click-chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC) in PROTAC and bioconjugation synthesis.
- Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Suitable for PROTAC linker construction and bioconjugation chemistry.
- PEG8 spacer improves solubility and provides flexible linkage length.
- Contains two terminal alkynes for dual conjugation sites.
- Supplied in small, pre-weighed mg quantities for research applications.
Medchemexpress LLC 4,7,10,13,16-pentaoxanonadec-18-ynoic acid | 1245823-51-1 | MFCD22201536 | >=98.0% | 304.34 g/mol | C14H24O7 | 100 MG
Propargyl-PEG5-acid is an alkyne-terminated polyethylene glycol (PEG5) linker supplied as a liquid. It is designed for bioconjugation workflows and enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) to attach payloads to azide-functionalized molecules in applications such as antibody-drug conjugate and PROTAC assembly.
- Contains a terminal alkyne group for copper-catalyzed azide-alkyne cycloaddition.
- Provides a non-cleavable five-unit PEG spacer to increase solubility and reduce steric hindrance.
- Suitable for linker synthesis in ADC and PROTAC workflows and other click chemistry applications.
- Supplied as a liquid in laboratory-scale pack sizes for direct use in reactions.
Medchemexpress LLC Boc-Propargylamine | 92136-39-5 | 99.78% | C8H13NO2 | 100 G
N-Boc-Propargylamine is a biochemical reagent and organic compound for life science research. It serves as a click chemistry reagent, featuring an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Prepares triazolobenzylidene-thiazolopyrimidines, which act as CDC25 phosphatase inhibitors.
- Synthesizes beta-glucan polysaccharide analogs.
- Involved in the Pauson-Khand (PK) reaction of norbornadiene and N-Boc-propargylamine to create 4,5-dissubstituted cyclopentenones.
Medchemexpress LLC Boc-propargylamine | 92136-39-5 | 99.5% | C8H13NO2 | 10 G
N-Boc-Propargylamine is a biochemical reagent used as a biological material or organic compound for life science-related research. It is a click chemistry reagent, containing an alkyne group, that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- Used to prepare triazolobenzylidene-thiazolopyrimidines
- Acts as CDC25 phosphatase inhibitors
- Used for the synthesis of beta-glucan polysaccharide analogs
- Involved in the Pauson-Khand (PK) reaction to prepare 4,5-dissubstituted cyclopentenones