Acetylides
eMolecules 927-74-2 | 3-Butyn-1-ol | Medchem Express | MFCD00002955 | 70.091 | C4H6O | 98.000 | OCCC#C | 500mg | 797053353
3-Butyn-1-ol | Medchem Express | 927-74-2 | MFCD00002955 | 70.091 | C4H6O | 98.000 | OCCC#C | 500mg | 797053353
STA Pharmaceutical 2'-propargyl G(iBu) amidite | 10 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 10 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 250 mL Glass (28-400)
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 179.7 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
eMolecules 156425-08-0 | 4-Chloro-5-(trifluoromethoxy)benzene-1,2-diamine | MFCD23703477 | 1g
Ambeed | 5-(((S)-1-((2S4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-33-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentanoic acid | 50mg | 788438991 | A1595811 | 2172819-73-5 | 544.670 | C27H36N4O6S
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Medchemexpress LLC Propargyl-PEG4-CH2CO2-NHS | 2144777-76-2 | 343.33 | 250 MG
Propargyl-PEG4-CH2CO2-NHS is a PEG derivative containing both a propargyl group and an NHS group. It functions as an ADC linker, used in the synthesis of antibody-drug conjugates (ADCs). This compound is also a click chemistry reagent, possessing an alkyne group, which allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- PEG derivative with propargyl and NHS groups
- Functions as an ADC linker
- Used in the synthesis of antibody-drug conjugates (ADCs)
- Click chemistry reagent with an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Medchemexpress LLC Propargyl-peg2-oh | 7218-43-1 | 99.66% | 5 G
Propargyl-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of Thalidomide-O-PEG2-propargyl. This compound is a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. It has a molecular weight of 144.17 and a formula of C7H12O3. It appears as a colorless to light yellow liquid with a density of 1.06 g/cm3 and a purity of 99.66%.
- Peg-based protac linker
- Utilized in the synthesis of thalidomide-o-peg2-propargyl
- Click chemistry reagent
- Contains an alkyne group for cuaac reactions
- Intended for research use only
- Soluble in ethanol (≥ 100 mg/ml)
Medchemexpress LLC Propargyl-PEG3-OCH2-Boc | 888010-02-4 | >95.0% | 302.36 g/mol | C15H26O6 | 5 MG
Propargyl-PEG3-OCH2-Boc is a Boc-protected PEG3 linker bearing a terminal propargyl (alkyne) group. It is a click-chemistry building block used for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and is commonly applied in PROTAC synthesis, bioconjugation, and small-molecule linker assembly. The PEG3 spacer improves solubility and provides flexibility for efficient conjugation.
- Boc-protected terminal alkyne suitable for CuAAC click reactions.
- Three-unit PEG spacer enhances solubility and conformational flexibility.
- Suitable for PROTAC linker synthesis and general bioconjugation.
- Compatible with common organic solvents such as DMSO and DMF.
- Available in research-scale quantities for synthesis and optimization.
Medchemexpress LLC Propargyl-PEG2-MS | 943726-01-0 | 95.0% | 250 MG
Propargyl-PEG2-MS is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Participates in copper-catalyzed azide-alkyne cycloaddition with molecules possessing azide groups
Chemscene ChemScene | 2-Bromo-5-ethynylpyridine | 250MG | CS-0059696 | 0.98 | 569672-28-2| MFCD13189724 | 182.02
ChemScene | 2-Bromo-5-ethynylpyridine | 250MG | CS-0059696 | 0.98 | 569672-28-2| MFCD13189724 | 182.02
Medchemexpress LLC Propargyl-PEG2-Tos | 145916-41-2 | MFCD29764327 | >98.0% | C12H14O4S | 100 MG
Propargyl-PEG2-Tos is a laboratory chemical often used as a PROTAC linker for research applications. This compound is stable under recommended storage conditions. While essential for certain laboratory procedures, it is important to note that it may cause skin irritation, serious eye irritation, and respiratory irritation, requiring careful handling. It boasts a high purity of greater than 98.0%.
- Stable under recommended storage conditions
- May cause skin and serious eye irritation
- May cause respiratory irritation
- Suitable for laboratory use
- For research use only
- Purity greater than 98.0%
Medchemexpress LLC Propargyl-PEG4-acid | 1415800-32-6 | 97.0% | 10 G
Propargyl-PEG4-acid is a PEG-based PROTAC linker. It can be used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and analogue PROTAC 3, which causes BTK degradation. Propargyl-PEG4-acid is also a click chemistry reagent, featuring an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in synthesis of BTK-IAP PROTACs
- PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells
- Click chemistry reagent with Alkyne group
- Can undergo CuAAc with Azide groups
Medchemexpress LLC Propargyl-PEG4-CH2-methyl ester | 1872433-63-0 | 250 MG
Propargyl-PEG4-CH2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Peg-based protac linker
- Click chemistry reagent
- Contains an alkyne group
- Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups