Acetylides
![Medchemexpress LLC Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-(4-methylbenzenesulfonate) | 1119249-30-7 | 98.2% | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-(4-methylbenzenesulfonate) | 1119249-30-7 | 98.2% | 1 G
Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker that functions as a click chemistry reagent. It incorporates an alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. This linker can be utilized in the synthesis of molecules like Thalidomide-O-PEG2-propargyl.
- Utilized in the synthesis of molecules like Thalidomide-O-PEG2-propargyl.
- Functions as a click chemistry reagent.
- Incorporates an alkyne group.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups.
- A component in PROTACs, which exploit the ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC Bis-PEG1-C-PEG1-CH2COOH (PROTAC Linker 26) | 2358775-67-2 | 95.0% | 50 MG
Bis-PEG1-C-PEG1-CH2COOH, also known as PROTAC Linker 26, is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds designed to induce the degradation of target proteins by exploiting the intracellular ubiquitin-proteasome system, and they consist of two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. This product is intended for research use only.
- PEG-based PROTAC linker: can be used in the synthesis of PROTACs.
- Key component for PROTACs: PROTACs contain two different ligands connected by a linker, targeting an E3 ubiquitin ligase and the protein of interest.
- Induces protein degradation: PROTACs utilize the ubiquitin-proteasome system to selectively degrade target proteins.
eMolecules Propargyl Butylcarbamate | 76114-73-3 | MFCD06411065 | 500mg
Toronto Research Chemicals | Propargyl Butylcarbamate | 500mg | 483432557 | P762590 | | 76114-73-3 | MFCD06411065 | 155.197 | C8H13NO2
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Chem-Impex International, Inc. (2-Hydroxyethyl)acetylene | 927-74-2 | MFCD00002955 | 100G
(2-Hydroxyethyl)acetylene, 927-74-2, MFCD00002955, 100G
Medchemexpress LLC Bis-propargyl-PEG6 1g | 400775-35-1 | 1 G
Bis-propargyl-PEG6 is a short PEG spacer with terminal propargyl (alkyne) groups used as a linker or crosslinker in click chemistry, bioconjugation, and PROTAC synthesis. It provides flexible spacing with reactive alkyne handles suitable for copper-catalyzed azide-alkyne cycloaddition and related conjugation reactions.
- Terminal propargyl groups for click chemistry conjugation.
- PEG6 spacer provides flexibility and water solubility.
- Suitable for PROTAC linker design and bioconjugation workflows.
- Offered in a 1 g research pack for small-scale synthesis.
Medchemexpress LLC 3-Ethynylaniline | 54060-30-9 | 117.15 | 1 ML
3-Ethynylaniline is a biochemical reagent used as a biological material or organic compound in life science research. It functions as a click chemistry reagent due to its Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Click chemistry is a method for selectively, modularly, and efficiently synthesizing new compounds through heteroatom linking.
- Biochemical reagent for life science research
- Functions as a click chemistry reagent
- Contains an alkyne group for reactions
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
eMolecules 2-Chloro-5-(trifluoromethoxy)pyridine | 1206972-45-3 | MFCD18257007 | 1g
Ambeed | 2-Chloro-5-(trifluoromethoxy)pyridine | 1g | 588341521 | A142164 | | 1206972-45-3 | MFCD18257007 | 197.540 | C6H3ClF3NO
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eMolecules 2-METHYL-6-(TRIFLUOROMETHOXY)-1H-INDOLE | 57330-49-1 | MFCD11111712 | 1g
AstaTech | 2-METHYL-6-(TRIFLUOROMETHOXY)-1H-INDOLE | 1g | 200616773 | 69490 | 95.000 | 57330-49-1 | MFCD11111712 | 215.175 | C10H8F3NO
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Sigma Aldrich Fine Chemicals Biosciences 6-Chloro-1-hexyne 98% | 10297-06-0 | MFCD00013697 | 5ML
6-Chloro-1-hexyne 98% | Purity: 98% | Mol Wt: 116.59 | 10297-06-0 | MFCD00013697 | 5ML
eMolecules 2-Methyl-4-(trifluoromethoxy)phenol | 129676-67-1 | MFCD04972927 | 1g
Apollo Scientific | 2-Methyl-4-(trifluoromethoxy)phenol | 1g | 562457673 | PC8770 | 97.000 | 129676-67-1 | MFCD04972927 | 192.137 | C8H7F3O2
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Medchemexpress LLC 4,7,10,13,16-pentaoxanonadec-18-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester | 1393330-40-9 | MFCD22574798 | 98.0% | 401.41 g/mol | C18H27NO9 | 500 MG
Propargyl-PEG5-NHS ester is a bifunctional PEG linker reagent with an alkyne (propargyl) group for click chemistry and an N-hydroxysuccinimide (NHS) ester for amine conjugation. It is intended for laboratory bioconjugation workflows such as antibody-drug conjugate (ADC) and PROTAC synthesis.
- Contains a propargyl (alkyne) functional group for CuAAC click reactions.
- Has an NHS ester for efficient amine coupling to primary amines.
- Molecular weight 401.41 g/mol and formula C18H27NO9.
- Purity typically 98.0% as supplied.
- Supplied as a solid/liquid reagent for research use with recommended cold, light-protected storage.
Medchemexpress LLC Tert-butyl N-(5-hydroxypentyl)carbamate | 75178-90-4 | MFCD01862955 | >97.0% | 203.28 g·mol⁻1 | C10H21NO3 | 1 G
5-(Boc-amino)-1-pentanol is a Boc-protected 5-aminopentanol used as a versatile intermediate and linker in organic and medicinal chemistry. It contains a tert-butoxycarbonyl protected amine and a primary alcohol, enabling selective deprotection and further functionalization for synthesis of peptides, small molecules, and conjugates.
- Boc-protected amine enables selective deprotection workflows.
- Primary alcohol allows further derivatization and coupling reactions.
- High purity suitable for synthetic and medicinal chemistry applications.
- Defined storage stability in solvent and bulk formats.
- Useful as a linker for conjugation and building-block synthesis.
![Medchemexpress LLC Ethanamine, 2-[2-(2-propyn-1-yloxy)ethoxy]- | 944561-44-8 | MFCD19160595 | 99.6% | 143.18 g/mol | C7H13NO2 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202866.png-250.jpg)
Medchemexpress LLC Ethanamine, 2-[2-(2-propyn-1-yloxy)ethoxy]- | 944561-44-8 | MFCD19160595 | 99.6% | 143.18 g/mol | C7H13NO2 | 250 MG
Propargyl-PEG2-amine is a PEG-based propargyl-functionalized amine used as a short spacer linker for bioconjugation. It provides a terminal alkyne for click chemistry and a primary amine for conjugation, making it suitable for linker synthesis and medicinal chemistry research.
- Short PEG2 spacer with terminal alkyne for click chemistry.
- Primary amine for facile conjugation to activated esters and similar chemistries.
- High purity suitable for research-grade applications.
- Compact 250 MG packaging for laboratory-scale experiments.
- Soluble in common organic solvents used in synthesis and bioconjugation.
Sigma Aldrich Fine Chemicals Biosciences 2-Butyn-1-ol 98% | 764-01-2 | MFCD00002914 | 5G
2-Butyn-1-ol 98% | Purity: 98% | Mol Wt: 70.09 | 764-01-2 | MFCD00002914 | 5G