Acetylides
Medchemexpress LLC Propargyl-PEG3-amine | 932741-19-0 | ≥98.0% | 187.24 | 250 MG
Propargyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- PEG-based PROTAC linker
- Functions as a click chemistry reagent
- Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules containing azide groups
- Used in the synthesis of PROTACs
Aobchem 3-Butyn-1-ol 1-methanesulfonate | ≥95% | CAS 72486-09-0 | C5H8O3S | 5g
3-Butyn-1-ol 1-methanesulfonate | ≥95% | CAS 72486-09-0 | C5H8O3S | 5g
Medchemexpress LLC Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-(4-methylbenzenesulfonate) | 1119249-30-7 | 98.2% | 250 MG
Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker used in the synthesis of Thalidomide-O-PEG2-propargyl. It functions as a click chemistry reagent, incorporating an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an alkyne group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Can be used to synthesize Thalidomide-O-PEG2-propargyl
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Propargyl-PEG3-bromide | 203740-63-0 | 97.7% | 251.12 | 250 MG
Propargyl-PEG3-bromide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with Alkyne group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules containing Azide groups