Acetylides
4-(2-Propyn-1-yl)morpholine 98.0+%, TCI America™
CAS: 5799-76-8 Molecular Formula: C7H11NO Molecular Weight (g/mol): 125.171 MDL Number: MFCD00510919 InChI Key: OKDZHAQIKCVKFE-UHFFFAOYSA-N Synonym: 4-Propargylmorpholine PubChem CID: 412941 IUPAC Name: 4-prop-2-ynylmorpholine SMILES: C#CCN1CCOCC1
Medchemexpress LLC 3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol | 1422023-54-8 | ≥97.0% | 250 MG
Propargyl-PEG7-alcohol is a chemical compound identified by CAS number 1422023-54-8. It has a molecular formula of C17H32O8 and a molecular weight of 364.43. This compound is typically found as a colorless to light yellow liquid, with a purity of ≥97.0%. It is intended for research use only.
- Molecular formula: C17H32O8
- Molecular weight: 364.43
- Purity: ≥97.0%
- Appearance: colorless to light yellow liquid
- Storage for pure form: 3 years at -20°C, 2 years at 4°C
- Storage in solvent: 6 months at -80°C, 1 month at -20°C
Medchemexpress LLC Propargyl-PEG6-acid | 1951438-84-8 | ≥97.0% | 348.39 g/mol | C16H28O8 | 250 MG
Propargyl-PEG6-acid is a PEG-based linker and click chemistry reagent containing a terminal alkyne. It is used as a linker in PROTAC and ADC synthesis and for copper-catalyzed azide-alkyne cycloaddition (CuAAc) bioconjugation reactions.
- cleavable PEG6 linker suitable for PROTAC and ADC synthesis
- contains a terminal propargyl (alkyne) group for click chemistry
- high purity (≥97.0% by NMR) suitable for research applications
- molecular weight 348.39 g/mol, molecular formula C16H28O8
- storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month)
Medchemexpress LLC Propargyl-PEG2-amine | 944561-44-8 | 98.9% | 143.18 g/mol | C7H13NO2 | 500 MG
Propargyl-PEG2-amine is a PEG-based linker used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as a PEG-based PROTAC linker. It is supplied as a liquid reagent for bioconjugation and medicinal chemistry applications.
- Non-cleavable ADC and PROTAC linker for bioconjugation.
- PEG2 spacer with propargyl and amine functional groups.
- High purity (98.9%) suitable for synthesis.
- Liquid appearance, colorless to light yellow.
- Molecular weight 143.18 g/mol; formula C7H13NO2.
- Storage: refrigerate at 4°C, protect from light; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Propargyl-PEG1-NH2 250mg | 122116-12-5 | 99.13 | C5H9NO | 250 MG
Propargyl-PEG1-NH2 is an alkyne-terminated PEG1 amine linker supplied as a research reagent for chemical biology and bioconjugation applications. It is a low-molecular-weight building block with documented purity and handling guidance.
- Alkyne-terminated PEG1 amine for click chemistry and bioconjugation.
- Purity 98.8% as provided by the supplier.
- Molecular formula C5H9NO; molecular weight 99.13.
- Available in small pack sizes, including 250 MG.
- Store at 4°C and protect from light; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
- Supplied with a data sheet and safety data sheet for handling and storage information.
Medchemexpress LLC Propargyl-peg6-acid | 1951438-84-8 | 348.39 g/mol | C16H28O8 | 50 MG
Propargyl-PEG6-acid is a PEG6-based linker and click-chemistry reagent containing a terminal propargyl (alkyne) group and a carboxylic acid. It is used to introduce a PEG6 spacer in the synthesis of PROTACs and antibody-drug conjugates (ADCs) and undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation.
- Used as PEG6 spacer in PROTAC and ADC synthesis.
- Terminal alkyne enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Molecular weight 348.39 g/mol; formula C16H28O8.
- CAS number 1951438-84-8 for unambiguous identification.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Propargyl-PEG4-GGFG-DXd | 2762518-94-3 | MFCD01346226 | 100.0% | 1083.12 | C54H63FN8O15 | 100 MG
Propargyl-PEG4-GGFG-DXd is a drug-linker conjugate for antibody-drug conjugates (ADCs) that links an ADC linker to the DNA topoisomerase I inhibitor DXd and provides a propargyl handle for bioorthogonal conjugation.
- Molecular formula: C54H63FN8O15
- Molecular weight: 1083.12
- Cas number: 2762518-94-3
- Purity: 99.99%
- Appearance: solid, off-white to light yellow
- Storage: 4°C sealed, away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month
- Package size: available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg; larger sizes available by quote
Medchemexpress LLC Arecaidine propargyl ester hydrobromide | 116511-28-5 | MFCD00078566 | 99.5% | 260.13 g/mol | C10H14BrNO2 | 5 MG
Arecaidine propargyl ester hydrobromide is a research-grade small molecule that acts as an agonist of M2 muscarinic acetylcholine receptors and has been reported to induce apoptosis, increase reactive oxygen species, and cause G2/M cell-cycle arrest in certain tumor cell models.
- Purity: 99.5%.
- Appearance: white to off-white solid.
- Molecular weight: 260.13 g/mol.
- Chemical formula: C10H14BrNO2.
- Biological activity: M2 muscarinic receptor agonist; reported inhibition of tumor cell proliferation.
- Storage: store sealed at 4°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- Pack sizes: available in 1 mg, 5 mg, and 10 mg.
Medchemexpress LLC Propargyl-PEG8-NH2 | 1196732-52-1 | MFCD28334507 | ≥98.0% | 407.50 | C19H37NO8 | 100 MG
Propargyl-PEG8-NH2 is a PEG-based linker reagent used for bioconjugation, including PROTAC and ADC synthesis. It contains a terminal propargyl (alkyne) group and a primary amine, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) and amine coupling reactions. The compound is a liquid (colorless to light yellow), with a molecular weight of 407.50 and high purity for research applications.
- Contains terminal alkyne for CuAAC click chemistry.
- Contains primary amine for amide and other coupling reactions.
- PEG8 spacer adds hydrophilicity and flexibility.
- High purity (≥98.0%).
- Available in small and bulk package sizes, including 100 mg.
- Store at 4°C, protect from light, and keep under nitrogen; long-term storage in solvent at -80°C.
Medchemexpress LLC Ws-917 | 10 MG
WS-917 is a small-molecule research compound characterized as a potent, orally active ABCB1 (P-glycoprotein) modulator. It enhances ABCB1 ATPase activity, promotes CD8+ T-cell activation, and has been shown to potentiate the antitumor effect of paclitaxel when combined with anti-PD-1 therapy. Intended for research use; follow appropriate storage and handling.
- Potent, orally active ABCB1 modulator.
- Enhances ABCB1 ATPase activity.
- Promotes CD8+ T-cell activation.
- Shown to enhance paclitaxel antitumor effect in combination with anti-PD-1 therapy.
- Molecular formula C16H13N5OS2; molecular weight 355.44 g/mol.
- Recommended storage: 4°C under nitrogen; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month) under nitrogen.