Hydrobromides
eMolecules 62595-74-8 | 3-bromopiperidine-2,6-dione | Pharmablock | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 50g | 642185381
3-bromopiperidine-2,6-dione | Pharmablock | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 50g | 642185381
TARGETMOL CHEMICALS INC TC-E 5003 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 uM. Purity 97.01%
Apexbio Technology LLC NAN-190 hydrobromide 115338-32-4 10mg
NAN-190 hydrobromide (CAS 115338-32-4) is a selective antagonist of the serotonin 5-HT1A receptor functioning by inhibiting receptor-mediated signal transduction pathways In receptor binding assays NAN-190 hydrobromide demonstrates high affinity for 5-HT1A receptors and modulates neurotransmitter release This compound is frequently employed in neurobiology and psychiatric disorder studies to investigate 5-HT1A-related mechanisms serving as a valuable tool for elucidating serotonergic signaling and its implications in neural function and pathology
Medchemexpress LLC Galanthamine hydrobromide | 1953-04-4 | MFCD00067672 | 99.9% | C17H22BrNO3 | 100 MG
Galanthamine hydrobromide is a selective, reversible, and competitive alkaloid acetylcholinesterase (AChE) inhibitor with an IC50 of 0.35 μM. It also acts as a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, and α6β4 nicotinic receptors (nAChRs). This compound is developed for research related to Alzheimer's disease (AD).
- Selective, reversible, competitive AChE inhibitor
- Potent allosteric potentiating ligand for human nicotinic receptors
- Reduces cognitive deficits in APP23 mice
- Protects against Aβ toxicity in SH-SY5Y cells
Apexbio Technology LLC Arecoline hydrobromide 300-08-3 500mg
Arecoline hydrobromide (CAS 300-08-3) is a nicotinic alkaloid that acts as a partial agonist at muscarinic acetylcholine receptors M1 M4 In electrophysiological studies it significantly inhibits the hERG potassium channel current with an IC50 of 9 55 mol/L The compound s inhibitory effect on IhERG displays concentration time and voltage dependency with blockade intensity influenced by stimulation frequency Subcutaneous administration in mice yields an LD50 of 100 mg/kg Arecoline hydrobromide is utilized in research on cardiac electrophysiology and muscarinic receptor pharmacology particularly for investigating frequency- and state-dependent modulation of cardiac ion channels
eMolecules 62595-74-8 | 3-Bromopiperidine-2,6-dione | Ambeed | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 500g | 761013543
3-Bromopiperidine-2,6-dione | Ambeed | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 500g | 761013543
Medchemexpress LLC Halofuginone hydrobromide | 64924-67-0 | 495.59 | 50 MG
Halofuginone hydrobromide (RU-19110) is a Febrifugine derivative that acts as a competitive prolyl-tRNA synthetase inhibitor. It is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibiting TGF-β activity. This compound exhibits various biological effects, including anti-malarial, anti-inflammatory, anti-cancer, and anti-fibrosis activities. It also functions as a potent pulmonary vasodilator.
- Competitive prolyl-tRNA synthetase inhibitor.
- Inhibits type-I collagen synthesis.
- Attenuates osteoarthritis by inhibiting TGF-β activity.
- Potent pulmonary vasodilator, activating Kv channels and blocking Ca2+ channels.
- Exhibits anti-malarial, anti-inflammatory, anti-cancer, and anti-fibrosis effects.
- Decreases NRF2 protein levels in tumors.
- Partially reverses established pulmonary hypertension.
Medchemexpress LLC Burixafor hydrobromide | 1191450-19-7 | 98.0% | 769.01 | 100 MG
Burixafor (TG-0054) hydrobromide is a potent CXCR4 antagonist with a pIC50 of 7.4. It inhibits the binding of CXCL12 to CXCR4, antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2, and blocks the downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction. Burixafor hydrobromide mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from the bone marrow to the peripheral blood and can be used for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist with a pIC50 of 7.4
- Inhibits CXCL12 binding to CXCR4
- Antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2
- Blocks downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction
- Mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from bone marrow to peripheral blood
- Can be used for research on autologous hematopoietic stem cell transplantation (ASCT)
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 50 MG
Eletriptan hydrobromide (Eletriptan HBr) is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, with Ki values of 0.92 nM and 3.14 nM, respectively. It is for research use only and not sold to patients.
- 5-HT1B and 5-HT1D receptor agonist
- Antimigraine activity
Medchemexpress LLC Arecoline | 63-75-2 | 50 MG
Arecoline is a naturally occurring, brain-penetrant, and orally active psychoactive alkaloid. It acts as a partial agonist of both nicotinic and muscarinic acetylcholine receptors. It has been observed to induce stimulation, alertness, anxiolysis, and anti-parasitic effects, and can also induce oxidative stress.
- Naturally brain-penetrant and orally active psychoactive alkaloid.
- Partial agonist of nicotinic and muscarinic acetylcholine receptors.
- Exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects.
- High purity: 99.84%.
Medchemexpress LLC Galanthamine hydrobromide | 1953-04-4 | 99.9% | C17H22BrNO3 | 1 ML
Galanthamine hydrobromide is a selective, reversible, competitive, alkaloid AChE inhibitor (IC50 0.35 μM) and a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs). It is developed for Alzheimer's disease (AD) research.
- Selective, reversible, competitive, alkaloid AChE inhibitor.
- Potent allosteric potentiating ligand (APL) of human nAChRs.
- Developed for Alzheimer's disease (AD) research.
- Demonstrates 53-fold selectivity for AChE over butyrylcholinesterase.
- Inhibits Aβ 1-40 and Aβ 1-42 aggregation (50 μM).
- Protects against Aβ(1-40) and Aβ(1-42) toxicity in SH-SY5Y cells.
- Reduces Aβ(1-40)-induced cellular apoptosis.
- Reduces cognitive deficits in APP23 mice.
eMolecules 768-66-1 | 2,2,6,6-Tetramethylpiperidine | Combi-Blocks | MFCD00005985 | 141.258 | C9H19N | 95.000 | CC1(C)CCCC(C)(C)N1 | 5g | 296391144
2,2,6,6-Tetramethylpiperidine | Combi-Blocks | 768-66-1 | MFCD00005985 | 141.258 | C9H19N | 95.000 | CC1(C)CCCC(C)(C)N1 | 5g | 296391144
Medchemexpress LLC SCH-202676 (hydrobromide) | 265980-25-4 | 96.8% | 348.26 | 1 ML
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR). It demonstrates antiviral activity and inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
- Purity: 96.81%
- Appearance: Solid
- Color: White to off-white
- Solubility: DMSO: 10 mg/mL