Hydrobromides
Medchemexpress LLC Pyrithiamine (hydrobromide) | 534-64-5 | 96.6% | 5MG
Pyrithiamine (hydrobromide) | 534-64-5 | 96.6% | 5MG
Apexbio Technology LLC Arecoline hydrobromide 300-08-3 10mM (in 1mL DMSO)
Arecoline hydrobromide (CAS 300-08-3) is a nicotinic alkaloid that acts as a partial agonist at muscarinic acetylcholine receptors M1 M4 In electrophysiological studies it significantly inhibits the hERG potassium channel current with an IC50 of 9 55 mol/L The compound s inhibitory effect on IhERG displays concentration time and voltage dependency with blockade intensity influenced by stimulation frequency Subcutaneous administration in mice yields an LD50 of 100 mg/kg Arecoline hydrobromide is utilized in research on cardiac electrophysiology and muscarinic receptor pharmacology particularly for investigating frequency- and state-dependent modulation of cardiac ion channels
eMolecules 62595-74-8 | 3-bromopiperidine-2,6-dione | Pharmablock | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 2.5g | 686930241
3-bromopiperidine-2,6-dione | Pharmablock | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 2.5g | 686930241
eMolecules 180695-79-8 | TERT-BUTYL4-BROMOPIPERIDINE-1-CARBOXYLATE | AstaTech | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 112534061
TERT-BUTYL4-BROMOPIPERIDINE-1-CARBOXYLATE | AstaTech | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 112534061
Medchemexpress LLC (RS)-AMPA hydrobromide | 171259-81-7 | 99.5% | 267.08 g/mol | C7H11BrN2O4 | 10 MG
(RS)-AMPA hydrobromide is the hydrobromide salt of (RS)-AMPA, a glutamate analogue and selective agonist of AMPA-type glutamate receptors. Supplied as a white to off-white solid for research use in neuroscience and pharmacology studies where a water-soluble AMPA receptor agonist is required.
- Selective AMPA receptor agonist.
- CAS number 171259-81-7.
- Molecular weight 267.08 g/mol.
- Purity 99.5%.
- White to off-white solid.
- Solubility: DMSO 50 mg/mL; H2O 5 mg/mL (may require ultrasonic).
- Storage: sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Burixafor (hydrobromide) | 1191450-19-7 | 98.0% | 769.01 | 1 ML
Burixafor hydrobromide is a potent CXCR4 antagonist that inhibits the binding of CXCL12 to CXCR4 and blocks downstream signaling. It mobilizes CD34+ hematopoietic stem/progenitor cells from bone marrow to peripheral blood. This compound is used for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist with a pIC50 of 7.4.
- Inhibits binding of CXCL12 to CXCR4.
- Mobilizes CD34+ hematopoietic stem/progenitor cells.
- Useful for research on autologous hematopoietic stem cell transplantation.
Apexbio Technology LLC SR 95531 hydrobromide 104104-50-9 50mg
SR 95531 hydrobromide (CAS 104104-50-9) also known as Gabazine is a selective competitive antagonist of the GABAA receptor By binding to the GABA recognition site on the receptor it blocks the activation induced by -aminobutyric acid (GABA) Experimental studies report an inhibitory concentration (IC50) of approximately 0 2 M for GABAA receptor-mediated responses Widely utilized in neuroscience research Gabazine is applied to investigate the physiological and pathological roles of GABAA receptor-mediated synaptic transmission neural network modulation and neurotransmitter regulation
Apexbio Technology LLC Homatropine Bromide 51-56-9 1g
Homatropine Bromide (CAS 51-56-9) is a small molecule antagonist of muscarinic acetylcholine receptors (AChRs) It selectively inhibits muscarinic receptor-mediated responses in endothelial and smooth muscle cells with reported IC50 values of 162 5 nM and 170 3 nM for WKY-E and SHR-E cell models respectively This compound serves as a valuable tool for investigating the role of muscarinic signaling in vascular function and smooth muscle physiology within experimental research settings
Medchemexpress LLC Remodelin hydrobromide | 1622921-15-6 | 99.6% | 363.28 | 100 MG
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It inhibits NAT10 activity, slows DNA replication, and suppresses the growth of prostate cancer cells. It has been shown to inhibit the growth of prostate cancer and hepatocellular carcinoma in xenograft models. Additionally, Remodelin hydrobromide enhances the healthspan in the Hutchinson-Gilford progeria syndrome (HGPS) mouse model.
- Inhibits NAT10 activity and cell proliferation in prostate cancer cells.
- Slows DNA replication.
- Suppresses the growth of prostate cancer cells.
- Inhibits the growth of hepatocellular carcinoma in xenograft models.
- Enhances healthspan in the HGPS mouse model.
- Decreases nuclear shape defects and increases genomic stability in fibroblasts.
Medchemexpress LLC Remodelin hydrobromide | 1622921-15-6 | 99.6% | 363.28 | 50 MG
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It works by inhibiting NAT10 activity, which in turn slows down DNA replication and suppresses the growth of prostate cancer cells. This compound has been shown to inhibit the growth of both prostate cancer and hepatocellular carcinoma in xenograft models. Additionally, it enhances the healthspan in a mouse model of Hutchinson-Gilford progeria syndrome (HGPS).
- Orally active and selective inhibitor.
- Inhibits NAT10 activity.
- Slows DNA replication.
- Suppresses growth of prostate cancer cells.
- Inhibits growth of hepatocellular carcinoma in xenograft models.
- Enhances healthspan in a mouse model of HGPS.
eMolecules 849928-26-3 | 1-Boc-3-Bromopiperidine | ChemScene | MFCD07779077 | 264.163 | C10H18BrNO2 | 95.000 | CC(C)(C)OC(=O)N1CCCC(Br)C1 | 25g | 859848138
1-Boc-3-Bromopiperidine | ChemScene | 849928-26-3 | MFCD07779077 | 264.163 | C10H18BrNO2 | 95.000 | CC(C)(C)OC(=O)N1CCCC(Br)C1 | 25g | 859848138
