Hydrobromides
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | MFCD08141806 | 463.43 g/mol | C22H27BrN2O2S | 10 MG
Eletriptan hydrobromide is the hydrobromide salt of eletriptan, a selective 5-HT1B and 5-HT1D receptor agonist supplied as an analytical standard for laboratory and research use.
- Analytical standard suitable for research and assay development.
- Selective 5-HT1B and 5-HT1D agonist for pharmacology studies.
- Reported Ki values: 0.92 nM (5-HT1B) and 3.14 nM (5-HT1D).
- Chemical formula C22H27BrN2O2S; molecular weight ~463.4 g/mol.
- Provided in small masses appropriate for analytical work.
Medchemexpress LLC NAN-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 10 MG
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist, specifically a selective antagonist of 5-HT1A receptors. It is primarily used for research purposes and has been shown to reverse the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats.
- Serotonin receptor 5-HT antagonist
- Selective antagonist of 5-HT1A receptor
- Reverses catalepsy-improving effect of fluoxetine
- For research use only
Medchemexpress LLC Vortioxetine (hydrobromide) | 960203-27-4 | C18H23BrN2S | 1 G
Vortioxetine hydrobromide (Lu AA 21004) is a multimodal serotonergic agent that acts as an antagonist of 5-HT3A (Ki: 3.7 nM) and 5-HT7 (Ki: 19 nM) receptors. It also inhibits the 5-hydroxytryptamine transporter (SERT) with a Ki of 1.6 nM. Furthermore, it functions as a 5-HT1A agonist (Ki: 15 nM) and a partial 5-HT1B agonist (Ki: 33 nM), exhibiting potent inhibition of SERT.
- Antagonist of 5-HT3A and 5-HT7 receptors
- Inhibitor of 5-hydroxytryptamine transporter (SERT)
- Acts as a 5-HT1A agonist
- Functions as a partial 5-HT1B agonist
- High purity of 99.87%
- Light yellow to yellow solid appearance
Medchemexpress LLC S-(2-aminoethyl) methanethiosulfonate hydrobromide | 16599-33-0 | 97.9% | 25 MG
MTSEA hydrobromide is a sulfhydryl-reactive reagent that selectively modifies free cysteine residues to introduce a positively charged side chain roughly the size of lysine. It is used in biochemical and electrophysiological studies to probe cysteine accessibility and to introduce charge at engineered cysteine sites.
- Sulfhydryl-reactive reagent for targeted cysteine modification.
- High supplied purity of 97.9%.
- Molecular weight 236.15 g/mol; formula C3H10BrNO2S2.
- Available in small solid packs suitable for research use.
- Store sealed at -20°C; in solution store at -80°C for long-term stability.
- CAS number 16599-33-0 for unambiguous identification.
TARGETMOL CHEMICALS INC Halofuginone hydrobromide 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibroproliferative diseases. Purity 98.5%
Medchemexpress LLC Guvacoline hydrobrom 10mg | 17210-51-4 | 222.08 g·mol⁻1 | C7H12BrNO2 | 10 MG
Guvacoline hydrobromide is the hydrobromide salt of guvacoline, a pyridine alkaloid that acts as a weak full agonist at atrial and ileal muscarinic acetylcholine receptors. This research-grade solid is provided for in vitro pharmacology and receptor-binding studies.
- High purity (96.09%) research-grade material.
- Molecular weight 222.08 g·mol⁻1; formula C7H12BrNO2.
- Suitable for muscarinic receptor pharmacology and neuropharmacology assays.
- Supplied as a 10 mg solid for small-scale experimental use.
Medchemexpress LLC L-2,4-diaminobutyric acid hydrobromide | 73143-97-2 | MFCD07368664 | 98.0% | 199.05 g/mol | C4H11BrN2O2 | 500 MG
L-2,4-diaminobutyric acid hydrobromide (L-DABA hydrobromide) is a research chemical described as a weak GABA transaminase inhibitor (IC50 > 500 μM) and reported to exhibit antitumor activity in vitro and in vivo. It is supplied as the hydrobromide salt, CAS 73143-97-2, with molecular weight 199.05 g/mol and reported purity 98.0%.
- High purity: 98.0%.
- Reported activity: weak GABA transaminase inhibitor (IC50 > 500 μM).
- Demonstrated antitumor activity in vitro and in vivo.
- Provided as hydrobromide salt for research use.
- Available in 500 mg pack size.
Medchemexpress LLC Fatostatin hydrobromide (125B11 hydrobromide) | 298197-04-3 | 99.5% | C18H19BrN2S | 200 MG
Fatostatin hydrobromide (125B11 hydrobromide) is a specific inhibitor of SREBP activation that impairs the activation of SREBP-1 and SREBP-2. It binds to SCAP (SREBP cleavage-activating protein) and inhibits the ER-Golgi translocation of SREBPs.
- Impairs the activation of SREBP-1 and SREBP-2
- Binds to SCAP (SREBP cleavage-activating protein)
- Inhibits ER-Golgi translocation of SREBPs
- Decreases transcription of lipogenic genes in cells
- Possesses antitumor properties
- Lowers hyperglycemia in ob/ob mice
- For research use only
Medchemexpress LLC SCH-202676 hydrobromide | 265980-25-4 | 96.8% | 348.26 g·mol⁻¹ | C15H14BrN3S | 5 MG
SCH-202676 hydrobromide is a small-molecule allosteric modulator of G protein-coupled receptors and adenosine receptors with reported antiviral activity, including inhibition of 3CLpro. The compound is supplied for research use in solid and solution forms and is intended for biochemical and pharmacological studies.
- Allosteric modulator of GPCRs and adenosine receptors.
- Reported antiviral activity; inhibits 3CLpro with low-micromolar potency.
- Available as solid and 10 mM solution in DMSO.
- High purity (96.81%).
- Molecular formula C15H14BrN3S; molecular weight 348.26 g·mol⁻¹.
- Store at -20°C long term; in solvent store at -80°C for extended stability.
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 25 MG
Eletriptan hydrobromide (Eletriptan HBr) is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity. It has Ki values of 0.92 nM for 5-HT1B receptors and 3.14 nM for 5-HT1D receptors.
- Dose-dependently reduces carotid blood flow in anesthetized dogs (1-1000 μg/kg; i.v.)
- Inhibits dural plasma protein extravasation in anesthetized rats (30-300 μg/kg; i.v.)
- Completely inhibits extravasation from the dura mater at 100 μg/kg
- Appears as an off-white to light brown solid
Medchemexpress LLC Pyrithiamine hydrobromide | 534-64-5 | 96.6% | 100 MG
Pyrithiamine hydrobromide is the hydrobromide salt of pyrithiamine, a thiamine metabolic inhibitor used in biochemical research. It serves as a substrate for thiamine pyrophosphokinase and is applied in studies of thiamine metabolism and nervous system disorders.
- Thiamine metabolic inhibitor used in biochemical research.
- Acts as a substrate for thiamine pyrophosphokinase.
- Useful in research on nervous system diseases and vitamin B1 metabolism.
- Chemical formula C14H20Br2N4O, molecular weight 420.14 g/mol.
- Supplied with high purity (≈96.6%).
- Available in small research quantities, including 100 mg.
Medchemexpress LLC Pifithrin-β hydrobromide | 511296-88-1 | MFCD02683960 | >=98.0% | 349.29 g/mol | C16H17BrN2S | 10 MG
Pifithrin-β hydrobromide is a small-molecule inhibitor of the p53 pathway supplied as the hydrobromide salt. It reversibly blocks p53 transcriptional activity (reported IC50 = 23 μM) and is used as a research tool in cellular and biochemical studies of apoptosis and ferroptosis. Chemical formula C16H17BrN2S; molecular weight 349.29 g/mol; CAS 511296-88-1.
- Reversible p53 inhibitor with reported IC50 of 23 μM.
- Hydrobromide salt for improved solubility and handling.
- Reported high purity (≥98% by HPLC) in supplier listings.
- Suitable for cellular and biochemical assays studying apoptosis and ferroptosis.
- Store sealed at 4 °C as a solid; in solution store at -80 °C for long-term stability.
Medchemexpress LLC S-EIT hydrobromide 25g
S-EIT (hydrobromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Apexbio Technology LLC Arecoline hydrobromide 300-08-3 1g
Arecoline hydrobromide (CAS 300-08-3) is a nicotinic alkaloid that acts as a partial agonist at muscarinic acetylcholine receptors M1 M4 In electrophysiological studies it significantly inhibits the hERG potassium channel current with an IC50 of 9 55 mol/L The compound s inhibitory effect on IhERG displays concentration time and voltage dependency with blockade intensity influenced by stimulation frequency Subcutaneous administration in mice yields an LD50 of 100 mg/kg Arecoline hydrobromide is utilized in research on cardiac electrophysiology and muscarinic receptor pharmacology particularly for investigating frequency- and state-dependent modulation of cardiac ion channels
Apexbio Technology LLC Arecoline hydrobromide 300-08-3 500mg
Arecoline hydrobromide (CAS 300-08-3) is a nicotinic alkaloid that acts as a partial agonist at muscarinic acetylcholine receptors M1 M4 In electrophysiological studies it significantly inhibits the hERG potassium channel current with an IC50 of 9 55 mol/L The compound s inhibitory effect on IhERG displays concentration time and voltage dependency with blockade intensity influenced by stimulation frequency Subcutaneous administration in mice yields an LD50 of 100 mg/kg Arecoline hydrobromide is utilized in research on cardiac electrophysiology and muscarinic receptor pharmacology particularly for investigating frequency- and state-dependent modulation of cardiac ion channels