Hydrochlorides
Medchemexpress LLC Anabasine (racemate) | 13078-04-1 | MFCD00006370 | 162.24 g/mol | C10H14N2 | 25 MG
(±) Anabasine is the racemic form of anabasine that acts as an agonist of the α7 nicotinic acetylcholine receptor and has reported anti-inflammatory and insecticidal activity.
- Racemic form (±) of anabasine.
- α7 nAChR agonist activity, used in receptor pharmacology studies.
- Reported anti-inflammatory and insecticidal properties.
- Suitable for biochemical and pharmacological research into nicotinic receptors.
- Provided as a small-mass research pack for laboratory use.
Medchemexpress LLC Mln120b dihydrochloride | 1782573-78-7 | 99.7% | 439.72 g·mol⁻¹ | C19H17Cl3N4O2 | 10 MG
MLN120B dihydrochloride is the dihydrochloride salt of MLN120B, a potent, ATP-competitive inhibitor of IKKβ used as a reference compound in NF-κB pathway and inflammatory disease research. It demonstrates an IC50 of approximately 60 nM against IKKβ and has been applied in biochemical, cellular, and in vivo studies. Supplied as a high-purity solid for laboratory research use only.
- Potent ATP-competitive inhibitor of IKKβ (IC50 ≈ 60 nM).
- Used in cellular and in vivo studies to inhibit multiple myeloma growth.
- High purity (≈99.7%).
- Suitable for biochemical and cellular assays.
- Available in small vials (5 mg, 10 mg, 25 mg, 50 mg).
- Intended for research use only; not for human or veterinary use.
eMolecules 7-(TRIFLUOROMETHYL)QUINOLIN-3-AMINE | 1402576-61-7 | MFCD28133454 | 1g
AstaTech | 7-(TRIFLUOROMETHYL)QUINOLIN-3-AMINE | 1g | 261435877 | 33223 | 95.000 | 1402576-61-7 | MFCD28133454 | 212.175 | C10H7F3N2
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Medchemexpress LLC PIM-447 dihydrochloride | 1820565-69-2 | MFCD30489747 | 99.3% | 513.38 | C24H25Cl2F3N4O | 10 MG
PIM-447 dihydrochloride is the dihydrochloride salt of a potent, orally available pan-PIM kinase inhibitor used in preclinical research. It modulates apoptosis and JAK/STAT signaling and has been investigated for antimyeloma and bone-protective effects. This reagent is supplied for laboratory research use only.
- Potent pan-PIM kinase inhibition with low picomolar Ki values.
- Demonstrated antimyeloma and bone-protective activity in preclinical studies.
- High solubility in water and DMSO (H2O: 50 mg/mL; DMSO: ≥46.7 mg/mL).
- High purity (≈99.3%).
- Provided as a 10 mg solid suitable for preparing concentrated stock solutions.
- Stability supported by recommended storage conditions in solvent (-80°C 1 year; -20°C 6 months).
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC 4-hydroxy-L-proline methyl ester hydrochloride | 40216-83-9 | MFCD00080855 | >97.0% | 181.62 | C6H12ClNO3 | 1 KG
H-Hyp-OMe hydrochloride is the methyl ester hydrochloride of trans-4-hydroxy-L-proline, used as a building block and non-cleavable linker in organic synthesis and bioconjugation.
- Used as a linker or building block in antibody-drug conjugate and PROTAC synthesis.
- Methyl ester hydrochloride form facilitates coupling reactions in organic synthesis.
- Available in bulk quantities suitable for scale-up reactions.
- Stable when stored sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
- Reported purity meets typical requirements for synthetic applications.
Medchemexpress LLC Harmalol hydrochloride | 6028-07-5 | 99.9% | 236.70 g/mol | C12H13ClN2O | 10 MG
Harmalol hydrochloride is the hydrochloride salt of harmalol, a beta-carboline alkaloid supplied for research use. It is reported to inhibit dioxin-mediated induction of CYP1A1 and to exhibit antioxidant and hydroxyl radical-scavenging activity.
- High purity: 99.91%.
- Hydrochloride salt form, solid, suitable for biochemical and pharmacological studies.
- Molecular formula C12H13ClN2O; molecular weight 236.70 g/mol.
- Provided in small research quantities appropriate for assay development and analytical testing.
- Store sealed at 4°C, protected from moisture and light; in solution store at -80°C (6 months) or -20°C (1 month).
Sigma Aldrich Fine Chemicals Biosciences o-Phenylenediamine dihydrochloride tablet, 15 mg substrate per tablet | 615-28-1 | MFCD00012966 | 50TAB
o-Phenylenediamine dihydrochloride tablet, 15 mg substrate per tablet | Mol Wt: 181.06 | 615-28-1 | MFCD00012966 | 50TAB
Medchemexpress LLC Naloxone hydrochloride | 357-08-4 | 100.0% | 363.84 | 100 MG
Naloxone hydrochloride is an antagonist of the Opioid receptor. It alleviates respiratory depression induced by opioid overdose, though it may also cause pulmonary edema and cardiac arrhythmias. It is intended for research use only and not for sale to patients.
- Opioid receptor antagonist
- Alleviates opioid-overdose-induced respiratory depression
- Data sheet, COA, SDS, and handling instructions provided
- Soluble in H2O (62.5 mg/mL) and DMSO (≥ 30 mg/mL)
Medchemexpress LLC PIM-447 (dihydrochloride) | 1820565-69-2 | 99.8% | 513.38 | 1 MG
PIM-447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor. With Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, it displays dual antimyeloma and bone-protective effects, and induces apoptosis. This compound is for research use only.
- Potent, orally available, and selective pan-PIM kinase inhibitor
- Inhibits PIM1, PIM2, and PIM3 with picomolar affinity
- Exhibits dual antimyeloma and bone-protective effects
- Induces apoptosis in multiple myeloma cells
- Increases annexin-V levels and promotes caspase cleavage
- Controls tumor progression in mouse models
Medchemexpress LLC PXS-4787 hydrochloride | 2409964-40-3 | C10H13ClFNO2S | 50 MG
PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor that abolishes lysyl oxidase activity. It inhibits various LOX isoforms and reduces the deposition and crosslinking of collagen I secreted by human fibroblasts. This compound, intended for research use only, appears as a white to off-white solid with 99.71% purity and can be dissolved in DMSO at 100 mg/mL.
- Specific and effective pan-LOX (lysyl oxidase) inhibitor
- Abolishes lysyl oxidase activity
- Inhibits various LOX isoforms (Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, rh LOXL4)
- Reduces deposition and crosslinking of collagen I
- White to off-white solid with 99.71% purity
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-benzenesulfonamide monohydrochloride | 402713-81-9 | >98.0% | 482.8 g·mol⁻¹ | C18H21Cl2N3O4S · HCl | 25 MG
SB-399885 hydrochloride is a research compound that acts as a selective antagonist of the serotonin 5-HT6 receptor (CAS 402713-81-9). It is used in vitro and in vivo to study 5-HT6-mediated signaling and cognitive effects, and is supplied as the monohydrochloride salt to improve solubility for biological assays.
- 5-HT6 receptor antagonist activity for receptor pharmacology studies.
- Reported high purity for reliable experimental results.
- Monohydrochloride salt form improves solubility in aqueous media.
- Suitable for in vitro and in vivo neuroscience applications.
- Supplied in small research pack sizes for dose-response and pilot studies.
Medchemexpress LLC BRL 52537 hydrochloride | 112282-24-3 | 98.1% | 391.76 | C18H25Cl3N2O | 25 MG
BRL 52537 hydrochloride is a selective κ-opioid receptor (KOR) agonist supplied as the hydrochloride salt for research use. It is commonly used in pharmacology and neuroscience studies to probe KOR-mediated signaling and investigate neuroprotective effects; the compound is provided with reported high purity suitable for preclinical laboratory experiments.
- Selective κ-opioid receptor agonist with high affinity.
- Supplied as the hydrochloride salt for research use.
- High reported purity suitable for laboratory experiments.
- Available in small pre-weighed quantities for convenient dosing.
- Used in pharmacology and neuroprotection research models.
Apexbio Technology LLC Dapoxetine HCl 129938-20-1 50mg
Dapoxetine hydrochloride (CAS 129938-20-1) is a short-acting selective serotonin reuptake inhibitor (SSRI) It exerts its pharmacological effect by inhibiting the reuptake of serotonin (5-HT) at the presynaptic membrane thereby increasing serotonin activity in the synaptic cleft This modulation of serotonergic neurotransmission has been shown to delay ejaculation latency making dapoxetine hydrochloride an established model compound for investigating serotonergic regulation of ejaculatory control It is widely used in research on the neurobiology and therapeutic approaches to premature ejaculation and related disorders
Medchemexpress LLC Anabasine ((S)-Anabasine) | 494-52-0 | 99.0% | 5 MG
Anabasine ((S)-Anabasine) is an alkaloid found as a minor component in tobacco (Nicotiana). It acts as a botanical pesticide nicotine and is a full agonist of nicotinic acetylcholine receptors (nAChRs). It induces depolarization of TE671 cells that endogenously express human fetal muscle-type nAChRs (EC50=0.7 μM).
- Found as a minor component in tobacco
- Acts as a botanical pesticide
- Full agonist of nicotinic acetylcholine receptors (nAChRs)
- Induces depolarization of TE671 cells
Medchemexpress LLC Benzamil hydrochloride | 161804-20-2 | 99.7% | 100 MG
Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). It is also a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 μM.
- Na+/Ca2+ exchanger (NCX) inhibitor
- Non-selective Deg/epithelial sodium channels (ENaC) blocker
- Can potentiate myogenic vasoconstriction
- Inhibits TRPP3-mediated Ca2+-activated currents