Vinyl halides
Medchemexpress LLC Dicloxacillin sodium | 343-55-5 | 98.0% | 25 MG
Dicloxacillin sodium is a β-lactam antibiotic belonging to the penicillin family. It is effective against Gram-positive bacteria and β-lactamase-producing organisms, such as Staphylococcus aureus.
- Effective against Gram-positive bacteria
- Active against β-lactamase-producing organisms
- Purity of 98.0%
- CAS No. 343-55-5
- Molecular Weight: 492.31
- Formula: C19H16Cl2N3NaO5S
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC 2-amino-3,5-dibromobenzaldehyde | 50910-55-9 | MFCD00671100 | 100.0% | 278.93 | C7H5Br2NO | 10 G
2-Amino-3,5-dibromobenzaldehyde (CAS 50910-55-9) is an organic biochemical reagent supplied as a light yellow solid. It is used as a synthetic intermediate and reference substance in research and analytical applications where high-purity aromatic aldehydes are required for synthesis, impurity profiling, and method development.
- High purity for analytical and synthetic work.
- Useful as a reference substance and impurity standard.
- Suitable for organic synthesis and intermediate preparation.
- Supplied as a solid with defined physical properties.
- Available in multiple pack sizes to support research workflows.
Medchemexpress LLC AS-Inclisiran sodium | 00-00-0 | 94.3% | C237H291F10N101O134P22S4 | 10MG
AS-Inclisiran sodium is an antisense oligonucleotide designed as the complementary strand to inclisiran to modulate PCSK9 expression for lipid-lowering research. Supplied as a white to off-white solid, it is intended for in vitro and preclinical studies.
- Molecular weight 7699.6 Da.
- Molecular formula C237H291F10N101O134P22S4.
- Targets PCSK9 (proprotein convertase subtilisin/kexin type 9).
- Purity approximately 94.3%.
- Soluble in water at ≥100 mg/mL.
- Store at -20°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
- Appearance white to off-white solid.
Medchemexpress LLC AS-Inclisiran sodium | 94.3% | C237H291F10N101O134P22S4 | 1 MG
AS-Inclisiran sodium is the antisense of Inclisiran, a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK9. It also inhibits Pyroptosis, activates PPARγ, and reduces NLRP3, cleaved caspase-1, IL-1β, and IL-18. It possesses anti-inflammatory, lipid-regulating, and anti-atherosclerotic activities. AS-Inclisiran sodium, as the antisense strand, lacks the complementary strand and its GalNAc modification, and therefore has no liver targeting property. It is for research use only and not sold to patients.
- Antisense of Inclisiran
- Inhibits transcription of PCSK9
- Inhibits pyroptosis
- Activates PPARγ
- Reduces NLRP3, cleaved caspase-1, IL-1β, and IL-18
- Possesses anti-inflammatory, lipid-regulating, and anti-atherosclerotic activities
- Lacks liver targeting property
Medchemexpress LLC TX1-85-1 | 1603845-32-4 | 99.7% | 580.68 | 1 MG
TX1-85-1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. It acts as the first selective Her3 ligand, forming a covalent bond with Cys721 in the ATP-binding site of Her3. This compound induces partial degradation of Her3 protein and attenuates Her3-dependent signaling, showing anti-proliferation effects in various cell lines.
- Irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM
- First selective Her3 ligand forming a covalent bond with Cys721
- Induces partial degradation of Her3 protein
- Attenuates Her3-dependent signaling
- Demonstrates anti-proliferation EC50s of 9.9, 11.5, and 16.9 μM for Ovcar8, HCC827 GR6, and PC9 GR4 cells, respectively
Sigma Aldrich Fine Chemicals Biosciences 1,2-Dibromoethylene, mixture of cis and trans 98% | 540-49-8 | MFCD00000184 | 25G
1,2-Dibromoethylene, mixture of cis and trans 98% | Purity: 98% | Mol Wt: 185.85 | 540-49-8 | MFCD00000184 | 25G
Medchemexpress LLC Rp-8-Br-cAMPS sodium | 925456-59-3 | 446.15 | 500 UG
Rp-8-Br-cAMPS sodium is an analog of cAMP and an inhibitor of PKA. It occupies cAMP binding sites on PKA type I regulatory subunits, which prevents PKA dissociation and activation. It can be used in the study of tumors and retrovirus-induced immune deficiency, and it also inhibits insulin secretion.
- Blocks the ability of 2-chloroadenosine to inhibit LAK cytotoxicity.
- Significantly reduces the inhibitory effect of 2-chloroadenosine on cytokine production.
- Inhibits insulin secretion in 832/13 cells.
- Improves immune function in a mouse retrovirus infection model.
- Strongly increases responses to the anti-CD3 mAb.
- Improved T cell responses.
Medchemexpress LLC CpG ODN 10101 (sodium) | 1234402-77-7 | 99.2% | 7,185.00 Da | 10 MG
CpG ODN 10101 (sodium) is a synthetic oligodeoxynucleotide that functions as a toll-like receptor 9 (TLR9) agonist. Supplied as the sodium salt for research use, it is employed to stimulate innate immune responses and study immunomodulatory effects, including cytokine production and B-cell activation.
- TLR9 agonist that stimulates dendritic cells and B cells.
- Induces interferon and proinflammatory cytokine production.
- Provided as a sodium salt to aid stability and handling.
- High purity suitable for research applications.
- Available in milligram-scale quantities for laboratory studies.
eMolecules 513-31-5 | 2,3-DIBROMOPROPENE | AstaTech | MFCD00000211 | 199.873 | C3H4Br2 | 90.000 | BrCC(Br)=C | 25g | 449762248
2,3-DIBROMOPROPENE | AstaTech | 513-31-5 | MFCD00000211 | 199.873 | C3H4Br2 | 90.000 | BrCC(Br)=C | 25g | 449762248