Vinyl halides
Medchemexpress LLC Adenosine, 8-bromo-, cyclic 3',5'-[hydrogen P(S)]-phosphorothioate], sodium salt (1:1) | 1573115-90-8 | 99.9% | 446.15 | 500 UG
Sp-8-Br-cAMPS sodium is a cAMP analog that activates protein kinase A (PKA). It is known to inhibit T-cell proliferation and the haemocyte non-self response in Lepidoptera larvae. This compound also inhibits phagocytosis of certain bacteria and modulates cytokine expression.
- Activates protein kinase A (PKA) with an EC50 of 360 nM
- Inhibits T-cell proliferation
- Inhibits haemocyte non-self response in Lepidoptera larvae
- Inhibits phagocytosis of *X. nematophila* and *B. subtilis*
- Modulates cytokine expression (IFN-γ, TNF-α, IL-2, IL-4)
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 100 MG
Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor.
- Causes cell-cycle arrest and selectively induces apoptosis in cancer cells by attenuating PI3K/Akt signaling.
- Antiproliferative activity correlates with CK2α catalytic subunit expression.
- Prevents leukemic cells from engaging UPR during PS-341 treatment, reducing BIP/Grp78 expression.
- Induces cytotoxicity and apoptosis, exerting anti-proliferative effects in hematological tumors.
- Demonstrates robust antitumor activity and reduces phospho-p21 (T145) in murine xenograft models.
Cayman Chemical DmyoInositol1phosphate sodiu
A synthetic, pure phosphoinositol for signal transduction research; can be formed by PLC hydrolysis of phosphatidylinositol or by dephosphorylation of polyphosphate inositols such as Ins(1,3)P2 by inositol polyphosphate 3-phosphatase
Matrix Scientific 2-BROMO-2-BUTENE-25G
2-Bromo-2-butene, 98%; 25g,C4H7Br, MFCD00000141, mw 135.01, [13294-71-8]
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 5 MG
Silmitasertib sodium salt is an orally bioavailable, highly selective, and potent CK2 inhibitor (IC50 values of 1 nM against CK2α and CK2α'). It induces cell-cycle arrest and selectively causes apoptosis in cancer cells, attenuates PI3K/Akt signaling, and demonstrates antiproliferative activity correlating with CK2α catalytic subunit expression. It also prevents leukemic cells from engaging a functional UPR to buffer proteotoxic stress and decreases pro-survival ER chaperon BIP/Grp78 expression.
- Causes cell-cycle arrest
- Induces apoptosis in cancer cells
- Attenuates PI3K/Akt signaling
- Exhibits antiproliferative activity
- Prevents leukemic cells from engaging a functional UPR
- Decreases pro-survival ER chaperon BIP/Grp78 expression
- Induces cytotoxicity
- Suppresses CK2-mediated PI3K/Akt/mTOR signaling pathways
- Demonstrates robust antitumor activity in murine xenograft models
Cayman Chemical DmyoInositol3phosphate sodiu
Synthetic, pure phosphoinositol for signal transduction research; can be formed by the dephosphorylation of polyphosphate inositols such as Ins(3,4)P2 by inositol polyphosphate 4-phosphatase
Sigma Aldrich Fine Chemicals Biosciences Bromomaleic anhydride 9750G
BROMOMALEIC Bromomaleic anhydride 9750G
Cayman Chemical DmyoInositol1phosphate sodiu
A synthetic, pure phosphoinositol for signal transduction research; can be formed by PLC hydrolysis of phosphatidylinositol or by dephosphorylation of polyphosphate inositols such as Ins(1,3)P2 by inositol polyphosphate 3-phosphatase
Medchemexpress LLC Trans-2-butene-1,4-dicarboxylic acid | 4436-74-2 | 99.17% | 100 MG
Trans-2-butene-1,4-dicarboxylic acid is an endogenous metabolite. It is for research use only and not sold to patients. It is also described as a metabolite for organic acidurias that can be found in urine.
- Endogenous metabolite
- Metabolite for organic acidurias
- Found in urine
- White to off-white solid
- Chemical formula: C6H8O4
- Molecular weight: 144.13
- Classified as ketone, aldehyde, and acid
Accela Chembio Inc 2-bromoindene | 5g | 10485-09-3 | MFCD06797863 | 98% | Shelf Life: 1800 Days | Light Sensitive
2-bromoindene | 5g | 10485-09-3 | MFCD06797863 | 98% | Shelf Life: 1800 Days | Light Sensitive
Medchemexpress LLC Trans-2-butene-1,4-dicarboxylic acid | 4436-74-2 | 99.2% | 1 ML
Trans-2-butene-1,4-dicarboxylic acid is an endogenous metabolite appearing as a white to off-white solid. This product is strictly for research use.
- Endogenous metabolite
- For research use only
- Metabolite for organic acidurias found in urine