Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC 1,11-Bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 50 MG
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BM-PEG3 is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). PROTACs are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This compound has a molecular weight of 352.34 and a chemical formula of C16H20N2O7, appearing as a white to light yellow solid. It is soluble in DMSO, with recommendations for proper storage and handling for both powder and solvent forms.
- It is a polyethylene glycol-based linker.
- It is used in the synthesis of proteolysis-targeting chimeras.
- It aids in the degradation of target proteins.
- It has a high purity of 98.0%.
- It is available as a white to light yellow solid.
- It can be dissolved in DMSO for in vitro experiments.
- It can be formulated for in vivo studies using specific co-solvents like DMSO and corn oil.
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Medchemexpress LLC N-Boc-C1-PEG3-C3-NH2 | 194920-62-2 | 320.42 | 5 G
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N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is for research use only.
- This product is a PEG-based PROTAC linker.
- PROTACs are composed of two different ligands linked together; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein.
- PROTACs function by utilizing the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
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Medchemexpress LLC TFP-PEG3-TFP 50mg
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TFP-PEG3-TFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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eMolecules 867062-95-1 | Fmoc-NH-PEG3-CH2CH2COOH | Ambeed | MFCD06656471 | 443.496 | C24H29NO7 | 97.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 100mg | 490533340
Fmoc-NH-PEG3-CH2CH2COOH | Ambeed | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 97.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 100mg | 490533340
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eMolecules 867062-95-1 | Fmoc-NH-PEG3-CH2CH2COOH | Ambeed | MFCD06656471 | 443.496 | C24H29NO7 | 97.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 490533341
Fmoc-NH-PEG3-CH2CH2COOH | Ambeed | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 97.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 490533341
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eMolecules 867062-95-1 | Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 572245282
Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 572245282
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eMolecules 867062-95-1 | Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 25g | 596090330
Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 25g | 596090330
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Medchemexpress LLC m-PEG3-CH2CH2COOH | 67319-28-2 | MFCD11041124 | 97.0% | 236.26 g·mol⁻¹ | C10H20O6 | 5 G
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m-PEG3-CH2CH2COOH is a methoxy-terminated PEG3 carboxylic acid used as a short, flexible spacer for bioconjugation chemistry. It is employed as a non-cleavable linker in antibody-drug conjugate (ADC) assembly and as a PEG-based linker in PROTAC and other conjugation workflows, providing a terminal carboxylic acid for coupling reactions and improving solubility of conjugates.
- Methoxy-terminated PEG3 spacer providing flexibility.
- Terminal carboxylic acid suitable for amide coupling and esterification.
- Molecular weight 236.26 g·mol⁻¹ for predictable spacer length.
- High purity (approximately 97.0%) suitable for research applications.
- Available in small research-scale quantities and recommended refrigerated storage for stability.
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eMolecules 77544-68-4 | Tos-PEG3 | Medchem Express (US) | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 1g | 849371126
Tos-PEG3 | Medchem Express (US) | 77544-68-4 | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 1g | 849371126
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Medchemexpress LLC NH2-PEG5-C6-Cl hydrochloride | 2241669-16-7 | 97.0% | 250 MG
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NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which are molecules that contain two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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Medchemexpress LLC Folate-PEG3-C2-acid | 97.6% | 644.63 g/mol | C28H36N8O10 | 10 MG
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Folate-PEG3-C2-acid is the acid fragment of a folate-PEG3-based NHS ester and serves as a PEG-type PROTAC linker building block used in the synthesis of PROTAC molecules and folate-conjugated ligands for receptor-targeting studies.
- Purity: 97.6%.
- Molecular weight: 644.63 g/mol.
- Solubility: soluble in DMSO at 33.33 mg/mL (51.70 mM); ultrasonication and heating may aid dissolution.
- Storage: store at 4°C protected from light; in solvent keep at -80°C (6 months) or -20°C (1 month), protected from light.
- Physical state: light yellow to yellow solid.
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Medchemexpress LLC N-(Azido-PEG3)-N-Boc-PEG4-Boc | 2112731-94-7 | C28H54N4O11 | 100 MG
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N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker. It is a click chemistry reagent that contains an Azide group.
- Can be used in the synthesis of PROTACs.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Medchemexpress LLC N-(acid-PEG3)-N-bis(PEG3-azide) | 2182602-17-9 | 98.1% | C25H49N7O11 | 100 MG
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N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker for PROTAC synthesis
- Click chemistry reagent with an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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Medchemexpress LLC BCN-exo-PEG3-NH2 | 1841134-72-2 | 99.9% | 368.47 | 250 MG
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BCN-exo-PEG3-NH2 is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Purity: 99.94%
- Molecular weight: 368.47
- Chemical formula: C19H32N2O5
- CAS number: 1841134-72-2
- Appearance: Colorless to light yellow liquid
- Density: 1.14±0.1 g/cm3
- Used in PROTAC synthesis
- Contains a BCN group for SPAAC reactions
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Medchemexpress LLC Nh2-peg3 (protac linker 35) | 6338-55-2 | MFCD07367495 | 149.19 | 1 G
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NH2-PEG3 (PROTAC Linker 35) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. This compound can be used in the synthesis of the PROTAC (β-NF-JQ1).
- PROTAC linker
- Polyethylene glycol (PEG) linker
- Suitable for synthesis of PROTAC (β-NF-JQ1)
- Colorless to light yellow liquid
- Purity: 99.87%
- Molecular weight: 149.19
- CAS number: 6338-55-2
- Density: 1.0773 g/cm3
- Solubility in DMSO: 100 mg/mL
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