Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine | 2347517-69-3 | 98.6% | C41H46N6O6S | 10MG
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(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a PROTAC small-molecule research reagent that induces ubiquitination and degradation of Smad3 while modulating HIF-α protein levels. It is intended for preclinical studies of anti-fibrosis, renal protection, and oncology mechanisms and is supplied as a high-purity solid.
- High purity (98.6%) for reliable experimental results.
- Dual-target PROTAC mechanism induces Smad3 degradation and modulates HIF-α levels.
- Suitable for preclinical research in fibrosis, renal protection, and oncology.
- Supplied as a solid and available in small research pack sizes for screening and synthesis.
- High solubility in DMSO (≥170 mg/mL) for convenient stock preparation.
- Stable under recommended storage conditions to preserve activity.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 3- TERT-BUTYLDIMETHYLSIL 100G
5000216096 3- TERT-BUTYLDIMETHYLSIL 100G
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Medchemexpress LLC (S,R,S)-AHPC-C6-PEG3-C4-Cl | 1835705-55-9 | MFCD31560478 | 97.0% | 751.42 | C38H59ClN4O7S | 1 G
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(S,R,S)-AHPC-C6-PEG3-C4-Cl is a VHL ligand-linker conjugate designed as a building block for PROTAC synthesis and ligand-linker conjugate development in targeted protein degradation research. It contains an (S,R,S)-configured AHPC VHL ligand connected via a six-carbon PEG3 linker with a terminal chloro group to enable downstream conjugation.
- Useful as a VHL (E3 ligase) ligand building block for degrader design.
- C6-PEG3 linker provides flexibility and spacer length for bifunctional molecules.
- Terminal chloro group enables nucleophilic substitution or further functionalization.
- Characterized by analytical data including HPLC and LC-MS for batch confirmation.
- Provided as a solid suitable for synthetic chemistry workflows and storage under controlled conditions.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000341716 THP-PEG5-OH 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000356957 N- AZIDO-PEG3 -N-BIS 100MG
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Medchemexpress LLC SB290157 trifluoroacetate | 1140525-25-2 | MFCD04974198 | 99.8% | 526.51 g/mol | C24H29F3N4O6 | 10 MG
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SB290157 trifluoroacetate is a selective antagonist of the complement C3a receptor (C3aR) used in research to probe C3a-mediated signaling. The compound is supplied as the trifluoroacetate salt, with reported in vitro potency (IC50 200 nM) and high chemical purity for laboratory studies.
- Selective C3a receptor antagonist with reported IC50 of 200 nM.
- Supplied as the trifluoroacetate salt.
- Molecular formula C24H29F3N4O6; molecular weight 526.51 g/mol.
- High purity (≈99.8%).
- Available in milligram-scale packages for laboratory use.
- For research use only; not for human or veterinary use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000349579 MAL-AMIDO-PEG3-ACID 100MG
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Chem-Impex International, Inc. 1-(Trimethylsilyl)imidazole | MFCD00005280 | 250G
1-(Trimethylsilyl)imidazole, MFCD00005280, 250G
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Chem-Impex International, Inc. 1-(Trimethylsilyl)imidazole | MFCD00005280 | 100G
1-(Trimethylsilyl)imidazole, MFCD00005280, 100G
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Medchemexpress LLC Pomalidomide-PEG3-azide | 2267306-15-8 | MFCD32198606 | >98.0% | C21H24N6O8 | 10MG
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Pomalidomide-PEG3-azide is an E3 ligase ligand-linker conjugate used as a building block in PROTAC synthesis and bioconjugation. It pairs a pomalidomide-derived cereblon-binding moiety with a three-unit polyethylene glycol linker terminated by an azide, enabling modular assembly of degrader molecules and efficient azide-alkyne click chemistry.
- Azide functional group for click chemistry conjugation
- PEG3 linker provides flexibility and solubility
- Cereblon-binding ligand supports targeted protein degradation
- High reported purity for reliable synthesis
- Suitable for PROTAC assembly and chemical probe development
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules BOC-NH-PEG3 500MG
5000191130 BOC-NH-PEG3 500MG
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eMolecules 1-METHOXY-1-TRIMETHYLSILYL 10G
5000217316 1-METHOXY-1-TRIMETHYLSILYL 10G
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Medchemexpress LLC ATN-161 trifluoroacetate salt | 904763-27-5 | 99.0% | 711.67 g/mol | C25H36F3N9O10S | 5 MG
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ATN-161 trifluoroacetate salt is a synthetic peptide integrin α5β1 antagonist supplied for research use. It inhibits angiogenesis and reduces liver metastasis growth in murine models. The trifluoroacetate salt is provided as a high-purity solid powder suitable for biochemical and in vivo studies.
- Integrin α5β1 antagonist activity demonstrated in murine models.
- High purity (99.0%) suitable for research applications.
- Supplied as a white to off-white solid for easy handling and storage.
- Available in small research pack sizes for dose-response and pilot studies.
- Intended for laboratory research use only.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Eggggg-peg8-amide-bis(deoxyglucitol) | 2842855-38-1 | 98.9% | 1254.29 g/mol | C49H91N9O28 | 10 MG
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EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable antibody-drug conjugate (ADC) linker for research applications. It provides a hydrophilic, cleavable spacer that combines PEG and deoxyglucitol moieties to facilitate conjugation, improve solubility, and enable controlled payload release.
- High purity (98.9%).
- Hydrophilic PEG-deoxyglucitol spacer enhances solubility.
- Cleavable linker chemistry suitable for controlled payload release.
- Soluble in DMSO at elevated temperature (75 mg/mL with warming).
- Supplied as a white to off-white solid-liquid mixture for handling.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules EMOLECULES INC
5000191408 TERT-BUTYL-2-IODOETHOXY 50MG
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