Organo-Metalloid Compounds
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- (115)
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Filtered Search Results
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 5 G
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Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports. PROTACs consist of two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, and they exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- PROTACs degrade target proteins using the ubiquitin-proteasome system.
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Medchemexpress LLC Bromoacetamido-PEG3-azide | 940005-81-2 | ≥97.0% | C10H19BrN4O4 | 25 MG
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Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
- Facilitates selective degradation of target proteins through the intracellular ubiquitin-proteasome system
- Intended for research use only
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eMolecules 252881-74-6 | NH2-PEG3-C2-Boc | ChemScene | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 10g | 582636019
NH2-PEG3-C2-Boc | ChemScene | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 10g | 582636019
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Medchemexpress LLC Bis-PEG5-acid 1g | 439114-13-3 | 338.35 g/mol | C14H26O9 | 1 G
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Bis-PEG5-acid is a polyethylene glycol (PEG) linker bearing two terminal carboxylic acid groups, used as a hydrophilic spacer in PROTAC construction and bioconjugation chemistry. It facilitates coupling reactions and improves aqueous solubility for assembled molecules.
- Two terminal carboxylic acid groups enable standard amide coupling reactions.
- PEG5 spacer provides hydrophilicity and conformational flexibility.
- Molecular weight 338.35 g/mol and formula C14H26O9 for precise stoichiometry.
- Suitable for PROTAC synthesis and general linker applications in medicinal chemistry.
- Offered in research quantities including 1 g for small-scale synthesis.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC NH2-PEG3 | 6338-55-2 | 149.19 | 100 G
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NH2-PEG3 (PROTAC Linker 35) is a PROTAC linker that belongs to the polyethylene glycol (PEG) linker family. It is used in the synthesis of PROTAC (β-NF-JQ1).
- PROTAC linker
- Can be used in the synthesis of PROTAC (β-NF-JQ1)
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eMolecules 252881-74-6 | H2N-PEG3-CH2CH2COOtBu | Acrotein ChemBio Inc. | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 25g | 771325778
H2N-PEG3-CH2CH2COOtBu | Acrotein ChemBio Inc. | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 25g | 771325778
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Medchemexpress LLC Amino-PEG3-C2-azido | 134179-38-7 | MFCD00269874 | 99.7% | 218.25 g/mol | C8H18N4O3 | 500 MG
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Amino-PEG3-C2-azido is a PEG-based PROTAC linker and click-chemistry reagent containing an azide functional group. It enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition for conjugation of azide- and alkyne-bearing fragments, making it suitable for linker assembly in degrader synthesis and bioconjugation workflows.
- High purity (99.67%) suitable for synthetic applications.
- Azide functionality enables CuAAC and SPAAC conjugations.
- Compatible with assembly of PROTAC linkers and bioconjugates.
- Molecular weight 218.25 g/mol; formula C8H18N4O3.
- Available in multiple pack sizes to support small- and larger-scale work.
- Store at -20°C, protect from light, under inert gas for stability.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g/mol | C10H21N3O5 | 25 G
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Azido-PEG5-alcohol is an azide-terminated polyethylene glycol (PEG) linker containing five ethylene glycol units that is used as a click-chemistry reagent and as a linker in bioconjugation workflows. It participates in copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions and is supplied for research use only.
- Azide functional group for click chemistry
- Five-unit PEG spacer adds hydrophilicity and flexibility
- Suitable for antibody-drug conjugate and PROTAC linker synthesis
- Characterized by NMR and LC-MS, purity >97.0%
- Available in multiple package sizes, including 25 G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC I-PEG5-OH 1g
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I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs and has applications in cancer-programmed cell death.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Applications in cancer-programmed cell death
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 50 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It can also be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Can be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 1-Propanamine, 3,3'-[oxybis(2,1-ethanediyloxy)]bis- | 4246-51-9 | >99.9% | 100 G
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Bis-NH2-C1-PEG3, also known as PROTAC Linker 24, is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Appearance: colorless to light yellow liquid
- Molecular formula: C10H24N2O3
- Molecular weight: 220.31
- Storage: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light)
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Medchemexpress LLC BM-PEG3 | 86099-06-1 | 98.0% | 100 MG
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BM-PEG3 is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are compounds that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They function by connecting two different ligands, one for an E3 ubiquitin ligase and another for the target protein, enabling targeted degradation.
- PEG-based PROTAC linker
- For research use only
- Purity: 98.0%
- Molecular weight: 352.34
- Molecular formula: C16H20N2O7
- Appearance: White to light yellow solid
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- Solubility in DMSO: 100 mg/mL (in vitro)
- Solubility in 10% DMSO, 90% corn oil: ≥ 2.5 mg/mL (in vivo)
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Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 hydrochloride | 2446474-09-3 | 96.6% | 25 MG
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Pomalidomide-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates the Pomalidomide based cereblon ligand
- Utilizes a 3-unit PEG linker
- Used in PROTAC technology
- Targets E3 Ligase Ligand-Linker Conjugates
- Pathway is PROTAC
- IC50 & Target is Cereblon
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Medchemexpress LLC 2,5,8,11,14-Pentaoxahexadecane, 16-bromo- | 854601-80-2 | 98.0% | C11H23BrO5 | 1 G
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m-PEG5-Br is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It facilitates the degradation of target proteins by exploiting the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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