Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Bis-PEG5-acid 1g | 439114-13-3 | 338.35 g/mol | C14H26O9 | 1 G
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Bis-PEG5-acid is a polyethylene glycol (PEG) linker bearing two terminal carboxylic acid groups, used as a hydrophilic spacer in PROTAC construction and bioconjugation chemistry. It facilitates coupling reactions and improves aqueous solubility for assembled molecules.
- Two terminal carboxylic acid groups enable standard amide coupling reactions.
- PEG5 spacer provides hydrophilicity and conformational flexibility.
- Molecular weight 338.35 g/mol and formula C14H26O9 for precise stoichiometry.
- Suitable for PROTAC synthesis and general linker applications in medicinal chemistry.
- Offered in research quantities including 1 g for small-scale synthesis.
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Medchemexpress LLC N- Azido-PEG3 -N-bis | 500MG
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N- Azido-PEG3 -N-bis | 500MG
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Medchemexpress LLC m-PEG5-NH2 | 5498-83-9 | 99.0% | C11H25NO5 | 250 MG
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m-PEG5-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules consisting of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These molecules function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and not sold to patients.
- Purity: 99.02%
- Molecular weight: 251.32
- Formula: C11H25NO5
- CAS number: 5498-83-9
- Appearance: Liquid (density: 1.023±0.06 g/cm³)
- Color: Colorless to light yellow
- SMILES: COCCOCCOCCOCCOCCN
- Leverages the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC NH2-PEG5-C6-Cl hydrochloride | 2241669-16-7 | 98.0% | 1 G
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NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Applicable in cancer and cancer targeted therapy research
- Classified as PROTAC linkers
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Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 50 MG
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs and has applications in cancer-programmed cell death.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Applications in cancer-programmed cell death
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Azido-PEG5-azide | 356046-26-9 | 99.98% | 332.36 | 500 MG
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Azido-PEG5-azide is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a versatile click chemistry reagent, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- For research use only
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Medchemexpress LLC DPC-681 | 284661-68-3 | 99.7% | 669.85 | 10 MM * 1 ML
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DPC-681 is a potent and selective inhibitor of HIV protease with IC90s for wild-type HIV-1 of 4 to 40 nM.
- Potent and selective inhibitor of HIV protease.
- Effective against wild-type HIV-1.
- Shows no loss in potency toward recombinant mutant HIVs with the D30N mutation.
- Exhibits a fivefold or smaller loss in potency toward mutant variants with three to five amino acid substitutions.
- Hepatic extraction can be saturated in dogs, leading to increased bioavailability at higher doses.
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Medchemexpress LLC 1,11-Bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 250 MG
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BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands
- One ligand for E3 ubiquitin ligase
- Other ligand for target protein
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Azido-PEG3-C6-Cl | 1625717-44-3 | MFCD34471373 | 95.3% | C12H24ClN3O3 | 10MG
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Azido-PEG3-C6-Cl is a PEG-based PROTAC linker and click-chemistry reagent containing an azide functional group. It has molecular formula C12H24ClN3O3, molecular weight 293.79 g/mol, and reported purity 95.3%. The product is a colorless to light-yellow liquid supplied in small milligram pack sizes for research use and is stored at -20°C in pure form (stable up to 3 years).
- Acts as a PEG-based linker for PROTAC and conjugate synthesis.
- Contains an azide group compatible with CuAAC and strain-promoted click reactions.
- Reported purity of 95.3% suitable for research applications.
- Available in small pack sizes for synthetic and screening workflows.
- Stable when stored at recommended temperatures, enabling longer-term storage.
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TARGETMOL CHEMICALS INC SX-682 10MG
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Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SX-682 is a potent selective and orally bioavailable inhibitor of CXCR1/2 has the potential to treat castration-resistant prostate cancer. purity: 99%
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Medchemexpress LLC (S,R,S)-Ahpc-C6-Peg3-C4-Cl | 1835705-55-9 | MFCD31560478 | ≥95.0% | 751.42 g/mol | C38H59ClN4O7S | 500 MG
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(S,R,S)-AHPC-C6-PEG3-C4-Cl is a VHL ligand-linker conjugate used as a building block in targeted protein degradation (PROTAC) research. It supplies a halide-terminated PEG linker designed for coupling in degrader synthesis and related medicinal chemistry applications.
- Used as a VHL ligand-linker building block for PROTAC synthesis.
- Molecular formula C38H59ClN4O7S.
- Molecular weight 751.42 g/mol.
- Purity ≥95.0% (manufacturer assay).
- Supplied as a 500 mg solid.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Bromoacetamido-PEG3-NH-Boc | 1421933-39-2 | ≥98.0% | C15H29BrN2O6 | 1 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs feature two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to the target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- PEG-based linker
- Utilized in the synthesis of PROTACs
- Connects ligands for E3 ubiquitin ligase and target proteins
- Enables selective degradation of target proteins
- Molecular weight: 413.30
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eMolecules 867062-95-1 | Fmoc-N-amido-PEG3-acid | Broadpharm | MFCD06656471 | 443.496 | C24H29NO7 | 98.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 208939971
Fmoc-N-amido-PEG3-acid | Broadpharm | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 98.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 208939971
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eMolecules 1076199-21-7 | N-BOC-PEG3-BROMIDE | AstaTech | MFCD09840081 | 356.257 | C13H26BrNO5 | 95.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCBr | 1g | 335880258
N-BOC-PEG3-BROMIDE | AstaTech | 1076199-21-7 | MFCD09840081 | 356.257 | C13H26BrNO5 | 95.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCBr | 1g | 335880258
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eMolecules 139115-92-7 | Boc-NH-PEG3 | Ambeed | MFCD07357496 | 249.307 | C11H23NO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCO | 100mg | 552604526
Boc-NH-PEG3 | Ambeed | 139115-92-7 | MFCD07357496 | 249.307 | C11H23NO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCO | 100mg | 552604526
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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