Tetrahydrofuran
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran suitable for HPLC, >=99.9%, inhibitor-free | 109-99-9 | MFCD00005356 | 4X4L
Tetrahydrofuran suitable for HPLC, >=99.9%, inhibitor-free | Purity: >=99.9% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 4X4L
Medchemexpress LLC 9,19-Cyclolanostan-3-ol, 24-methylene-, 3-(4-hydroxy-3-methoxyphenyl)-2-propenoate, (3β)- | 469-36-3 | 5 MG
24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. It promotes parvin-beta expression in human breast cancer cells and is a potential ATP-competitive Akt1 inhibitor.
- Purity of 98.53%
- White to off-white solid appearance
- Soluble in DMSO at ≥ 12.5 mg/mL
- Classified as a terpenoid and phenol
- Derived from plants
Medchemexpress LLC CIL62 | 117593-36-9 | 97.0% | 382.45 | 50 MG
CIL62 is a caspase-3/7-independent cell death inducer that operates via Necrostatin-1 dependent mechanisms. It exhibits antiproliferative activity against human COLO205, IMR32, and K562 cells.
- Caspase-3/7-independent cell death inducer
- Necrostatin-1 dependent mechanism of action
- Antiproliferative activity against COLO205, IMR32, and K562 cells
Medchemexpress LLC SJ10542 | 2789678-92-6 | 99.3% | C41H46N12O5S | 50 MG
SJ10542 is a potent and selective JAK2/3 PROTAC degrader. In PDX cells lSJBALL020589, SJ10542 has DC50 values of 14 and 11 nM for JAK2 and JAK3, respectively. It exhibits antitumor activity and can be used for the research of hematological malignancies and autoimmune diseases.
- Potent and selective JAK2/3 PROTAC degrader
- Exhibits antitumor activity
- Useful for research of hematological malignancies and autoimmune diseases
- Degrades JAK2 (DC50: 24 nM), JAK3, and GSPT1 in MHH-CALL-4 cells
- JAK2 DC50: 14 nM
- JAK3 DC50: 11 nM
- JAK2-fusion ALL DC50: 24 nM
- CRBN recruiter
Medchemexpress LLC VPC-70619 | 2361742-30-3 | 99.93% | C16H8ClF3N4O | 100 MG
VPC-70619 is a potent N-Myc inhibitor that blocks the binding of the N-Myc-Max heterocomplex to the DNA E-box and shows strong inhibitory activity against N-Myc-dependent cell lines. It can partially reverse paclitaxel resistance in cells by reducing MYCN expression and can be used for cancer research, including neuroblastoma and thyroid cancer.
- Potent N-Myc inhibitor
- Blocks the binding of the N-Myc-Max heterocomplex to the DNA E-box
- Shows strong inhibitory activity against N-Myc-dependent cell lines
- Partially reverses paclitaxel resistance by reducing MYCN expression
- Can be used for cancer research, including neuroblastoma and thyroid cancer
- Demonstrates high inhibition rates in certain cell types
- Highly stable in liver microsomes
- Regulates MYCN signaling pathway
- Inhibits proliferation, migration, and aggressiveness of cancer cells
Medchemexpress LLC PhosTAC7 | 3016307-75-5 | 99.23% | C58H87ClN2O17 | 50 MG
PhosTAC7 is a heterobifunctional molecule, also known as a Phosphorylation Targeting Chimera (PhosTAC). It is designed to dephosphorylate specific proteins by recruiting serine/threonine protein phosphatase 2A (PP2A), making it a valuable tool for various research applications.
- Selectively modulates the phosphorylation state of individual target proteins.
- Dephosphorylates PDCD4, FOXO3a, and tau proteins.
- Useful in research for cancer.
- Applicable in the study of tau protein-related neurodegenerative diseases, such as Alzheimer's.
- For research use only.
Medchemexpress LLC ETZ (C3-CA-DTZ) | 2989379-61-3 | 99.8% | C34H28N6O6 | 100 MG
ETZ (C3-CA-DTZ) is a promising luciferase substrate, acting as a prosubstrate that can be activated in vivo by non-specific esterase. This activation enhances the brain delivery of luciferin, making it a valuable tool for research applications. It has a molecular weight of 616.62 and a purity of 99.84%.
- Promising luciferase substrate
- Activated in vivo by non-specific esterase
- Enhances brain delivery of luciferin
- For research use only
Medchemexpress LLC Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide | 2361742-30-3 | 99.9% | C16H8ClF3N4O | 50 MG
Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide | 2361742-30-3 | 99.9% | C16H8ClF3N4O | 50 MG
Medchemexpress LLC 3-amino-4-{(3S)-3-[(2-ethoxyethoxy)methyl]piperidin-1-yl}thieno[2,3-b]pyridine-2-carboxamide | 2871872-79-4 | 99.9% | C18H26N4O3S | 50 MG
DS96432529 is a potent and orally active bone anabolic agent through CDK8 inhibition.
- Potent bone anabolic agent
- Orally active
- Inhibits CDK8
- For research use only
Medchemexpress LLC (S)-Tetrahydrofuran-3-ol | 86087-23-2 | MFCD00064327 | 99.9% | C4H8O2 | 25 G
(S)-Tetrahydrofuran-3-ol is the (S)-enantiomer of Tetrahydrofuran-3-ol. This chemical serves as a significant precursor for the creation of HIV protease inhibitors and can be manufactured through chemical synthesis or enzymatic hydrolysis.
- High purity of 99.94%
- Appears as a colorless to light yellow liquid
- Stable in pure form for 3 years at -20°C or 2 years at 4°C
- Stable in solvent for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide | 2922283-38-1 | 98.0% | C93H177N3O3 | 50 MG
N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3, an ionizable lipid-like material used for mRNA delivery. It presents as an oil, with a color ranging from off-white to light yellow.
- Analogue of TT3
- Ionizable lipid-like material
- Used for mRNA delivery
- Appears as an oil
- Off-white to light yellow color
Medchemexpress LLC Rhodojaponin III | 26342-66-5 | 5 MG
Rhodojaponin III is a diterpenoid extracted from the leaves of Rhododendron molle. It exhibits anti-inflammatory activity, demonstrated by its IC50 of 7 μM against LPS-induced nitric oxide production in mouse RAW264.7 cells. This compound has a molecular weight of 368.46 and a chemical formula of C20H32O6. It typically appears as a white to off-white solid.
- Extracted from the leaves of Rhododendron molle
- Exhibits anti-inflammatory activity
- Has an IC50 of 7 μM against LPS-induced nitric oxide production in mouse RAW264.7 cells
- Molecular weight is 368.46
- Chemical formula is C20H32O6
- Appears as a white to off-white solid
- Intended for research use only
Medchemexpress LLC DS96432529 | 2871872-79-4 | 99.9% | C18H26N4O3S | 100 MG
DS96432529 is a potent and orally active bone anabolic agent, acting through CDK8 inhibition. It is for research use only.
- Potent and orally active bone anabolic agent
- Acts through CDK8 inhibition
- Solid appearance
- Color: Off-white to pink
- Molecular weight: 378.49
- Chemical formula: C18H26N4O3S
- CAS number: 2871872-79-4
- For research use only
Medchemexpress LLC Zectivimod | 1623066-63-6 | 99.4% | 528.47 | 100 MG
Zectivimod is a sphingosine-1-phosphate receptor agonist. It is intended for research applications related to autoimmune diseases, chronic inflammatory diseases, and immunoregulation disorders.
- Sphingosine-1-phosphate receptor agonist
- Suitable for research on autoimmune diseases
- Suitable for research on chronic inflammatory diseases
- Suitable for research on immunoregulation disorders
- Solid appearance, white to off-white color
- Purity of 99.35%
- Store at 4°C, sealed, away from moisture and light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture and light
- Target LPL receptor
- Part of the GPCR/G protein pathway
- Solubility in DMSO: 100 mg/mL