Tetrahydrofuran
Medchemexpress LLC Taurohyodeoxycholic 50mg | 386523 | 50 MG
Taurohyodeoxycholic acid is a taurine-conjugated 6α-hydroxylated bile acid used in preclinical research to study liver disease, colitis, and biliary disorders. It exhibits anti-inflammatory effects, including reductions in MPO activity, TNF-α, and IL-6.
- Used to study nonalcoholic fatty liver disease and colitis.
- Shows anti-inflammatory activity in animal models.
- Available in multiple solid and solution pack sizes.
- Chemical formula C26H45NO6S; molecular weight 499.70 g/mol.
Medchemexpress LLC RS 09 | 1449566-36-2 | 99.83% | 691.78 | 10 MG
RS 09 is a peptide mimic of LPS and acts as a TLR4 agonist. It binds to TLR-4 and activates NF-κB, and can function as an adjuvant in vivo to enhance the antigen-specific immune response. This compound has been shown to stimulate TLR-4 and activate NF-κB in HEK-BLUE™-4 cells and induce nuclear translocation of NF-κB and secretion of inflammatory cytokines in RAW264.7 cells.
- Acts as a TLR4 agonist
- Binds to TLR-4 and activates NF-κB
- Enhances antigen-specific immune response in vivo
- Stimulates TLR-4 and activates NF-κB in HEK-BLUE™-4 cells
- Induces nuclear translocation of NF-κB and secretion of inflammatory cytokines in RAW264.7 cells
Medchemexpress LLC Az12601011 | 2748337-86-0 | 99.8% | 50 MG
AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor (also inhibits ALK4 and ALK7) used as a research reagent to study TGF-β signaling and tumor models. It inhibits SMAD2 phosphorylation with reported potency (IC50 18 nM; Kd 2.9 nM) and has shown antitumor activity in vivo. High-purity powder and DMSO stock solutions are available.
- Selective TGFBR1, ALK4, and ALK7 inhibition.
- Biochemical potency: IC50 18 nM; Kd 2.9 nM.
- High purity (99.78%).
- Available as powder and DMSO solution for in vitro studies.
- Recommended storage: powder -20°C for long term, and solutions -80°C.
Medchemexpress LLC Nerigliatin | 1245603-92-2 | MFCD26960571 | 99.9% | 432.43 g·mol⁻¹ | C22H20N6O4 | 100 MG
Nerigliatin is a small-molecule glucokinase activator provided for laboratory research use. It is used in preclinical studies to evaluate glucose-lowering effects and glucokinase modulation. Supplied as a powdered compound, it is intended for in vitro and in vivo research applications; not for human or veterinary use.
- Glucokinase activator for studying glucose metabolism.
- High purity (≈99.9%) suitable for analytical and biological assays.
- Chemical formula C22H20N6O4; molecular weight 432.43 g·mol⁻¹.
- Available in multiple pack sizes including 100 MG.
- For research use only; not intended for clinical or veterinary applications.
- Follow safety data sheet for handling and storage recommendations.
Medchemexpress LLC N'-(4-(diethylamino)-2-hydroxybenzylidene)isonicotinohydrazide | 140405-36-3 | MFCD00542031 | 99.7% | 312.37 g/mol | C17H20N4O2 | 10 MG
RSVA405 (CAS 140405-36-3) is a small-molecule activator of AMP-activated protein kinase (AMPK) used in cellular and biochemical research. It promotes CaMKKβ-dependent AMPK activation, inhibits mTOR signaling, and can induce autophagy; supplied at high purity for research applications.
- Potent AMPK activator; reported EC50 = 1 μM.
- High purity (~99.7%).
- Molecular formula C17H20N4O2; molecular weight 312.37 g/mol.
- Soluble in DMSO; available as solid or DMSO solution.
- For research use only; not for human consumption.
Medchemexpress LLC Gsk2983559 | 99.5% | 612.63 | 100 MG
GSK2983559 is an orally active and potent receptor interacting protein 2 (RIP2) kinase inhibitor. It blocks many proinflammatory cytokine responses both in vivo and in human inflammatory bowel disease explant samples.
eMolecules 121138-01-0 | 3-Iodotetrahydrofuran | Synthonix - Stock | MFCD09878873 | 198.003 | C4H7IO | 95.000 | IC1CCOC1 | 5g | 525918605
3-Iodotetrahydrofuran | Synthonix - Stock | 121138-01-0 | MFCD09878873 | 198.003 | C4H7IO | 95.000 | IC1CCOC1 | 5g | 525918605
Medchemexpress LLC (R)-Tetrahydrofuran-2-yl-methylamine | 7202-43-9 | ≥97.0% | 101.15 | 250 MG
(R)-Tetrahydrofuran-2-yl-methylamine (1-[(2R)-tetrahydrofuran-2-yl]methanamine) is a synthetic intermediate useful for pharmaceutical synthesis. It is for research use only.
- Molecular weight: 101.15
- CAS No.: 7202-43-9
- Formula: C5H11NO
- Appearance: Liquid
- Color: Colorless to light yellow
- Purity: ≥97.0%
Medchemexpress LLC PF-00446687 free bas 100mg | 862281-92-3 | 100MG
PF-00446687 is a potent selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 1 nM[1 Pf-446687 is brain penetrant[2
AARON CHEMICALS LLC DIMETHYL ISOSORBIDE, 500G
Dimethyl Isosorbide | Purity: 97% | Mol Wt: 174.1944 | 5306-85-4 | MFCD00064828 | 500g
eMolecules 121138-01-0 | 3-Iodotetrahydrofuran | Ambeed | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 5g | 600842501
3-Iodotetrahydrofuran | Ambeed | 121138-01-0 | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 5g | 600842501
eMolecules 121138-01-0 | 3-Iodotetrahydrofuran | Ambeed | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 25g | 582615058
3-Iodotetrahydrofuran | Ambeed | 121138-01-0 | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 25g | 582615058
Medchemexpress LLC (R)-Tetrahydrofuran-2-yl-methylamine | 7202-43-9 | ≥97.0% | 101.15 | 1 G
(R)-Tetrahydrofuran-2-yl-methylamine is a synthetic intermediate useful for pharmaceutical synthesis. It appears as a liquid, colorless to light yellow.
- Useful for pharmaceutical synthesis.
- Liquid appearance.
- Colorless to light yellow.
- For research use only.
Medchemexpress LLC SJ10542 | 2789678-92-6 | 99.3% | C41H46N12O5S | 50 MG
SJ10542 is a potent and selective JAK2/3 PROTAC degrader. In PDX cells lSJBALL020589, SJ10542 has DC50 values of 14 and 11 nM for JAK2 and JAK3, respectively. It exhibits antitumor activity and can be used for the research of hematological malignancies and autoimmune diseases.
- Potent and selective JAK2/3 PROTAC degrader
- Exhibits antitumor activity
- Useful for research of hematological malignancies and autoimmune diseases
- Degrades JAK2 (DC50: 24 nM), JAK3, and GSPT1 in MHH-CALL-4 cells
- JAK2 DC50: 14 nM
- JAK3 DC50: 11 nM
- JAK2-fusion ALL DC50: 24 nM
- CRBN recruiter