Prenol lipids
Medchemexpress LLC L-Glutamic acid, polymer with L-alanine, L-lysine and L-tyrosine, acetate (salt) | 147245-92-9 | 98.0% | 25 MG
L-Glutamic acid, polymer with L-alanine, L-lysine and L-tyrosine, acetate (salt) | 147245-92-9 | 98.0% | 25 MG
Medchemexpress LLC N2-(1H-Indol-5-yl)-6-(pyridin-4-yl)pyrazine-2,3-diamine acetate | 98.4% | 362.39 | 25 MG
AKN-028 acetate is a novel tyrosine kinase (TK) inhibitor and a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. It inhibits FLT3 autophosphorylation, induces a dose-dependent cytotoxic response (mean IC50=1 μM), and induces apoptosis by activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia (AML).
- Potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 of 6 nM.
- Inhibits FLT3 autophosphorylation.
- Induces dose-dependent cytotoxic response (mean IC50=1 μM).
- Induces apoptosis by activation of caspase 3.
- Inhibits growth of primary AML and MV4-11 cells in mice.
- Useful in research of acute myeloid leukemia (AML).
Enzo Life Sciences AG-879 (5mg). CAS: 148741-30-4
AG-879, a member of the tyrphostin family of tyrosine kinase inhibitors, inhibits NGF receptor (pp140c-trk) autophosphorylation selectively with no inhibition of EGF or PDGF receptor phosphorylation (IC50=10 µM). AG-879 inhibits NGF-induced neurite outgrowth in PC12 cells. Purity: ≥99% (HPLC). Solubility: Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences AG-879 (25mg). CAS: 148741-30-4
AG-879, a member of the tyrphostin family of tyrosine kinase inhibitors, inhibits NGF receptor (pp140c-trk) autophosphorylation selectively with no inhibition of EGF or PDGF receptor phosphorylation (IC50=10 µM). AG-879 inhibits NGF-induced neurite outgrowth in PC12 cells. Purity: ≥99% (HPLC). Solubility: Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml). Long Term Storage: -20°C.
Medchemexpress LLC Isotanshinone IIA | 20958-15-0 | 5 MG
Isotanshinone IIA is an abietane-type diterpene metabolite that non-competitively inhibits Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 of 11.4 μM. Intended for research use only, this product is an orange to orange-red solid with 98.0% purity. It has a molecular weight of 294.34 and a chemical formula of C19H18O3.
- Non-competitive inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) activity
- IC50 of 11.4 μM
- 98.0% purity
- Appears as an orange to orange-red solid
- Molecular weight of 294.34
- Chemical formula of C19H18O3
- Classified under Quinones and Naphthalene Quinones
- Powder storage: -20°C for 3 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 3 mg/mL (10.19 mM)
TARGETMOL CHEMICALS INC VITAMIN K2 25MG
Also available in 5 mg 10 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Vitamin K2 (Menatetrenone) is a menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signaling of certain tyrosine kinases thereby affecting several transcription factors including c-myc and c-fos. This agent inhibits tumor cell growth by inducing apoptosis and cell cycle arrest. purity: 99%
Medchemexpress LLC Isotanshinone IIA | 20958-15-0 | 1 MG
Isotanshinone IIA is an abietane-type diterpene metabolite. It functions as a non-competitive inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 of 11.4 μM. This compound appears as an orange to orange-red solid and is intended for research use only.
- High purity: 98.0%
- IC50: 11.4 μM for PTP1B
- Molecular weight: 294.34
- Chemical formula: C19H18O3
- Appearance: Solid
- Color: Orange to orange-red
- Structure classification: Quinones, Naphthalene Quinones
- Initial source: Plants Leguminosae Samanea saman (Jacq.) Merr., Plants Labiatae
- Solubility in DMSO: 3 mg/mL (10.19 mM)