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Organic compounds with acidic properties, organic acids are generally weak acids incapable of complete dissociation in water. Available in a range of chemical compositions and acid strengths, they can be used for various industrial and everyday applications.
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BPAM344 is a positive allosteric modulator (PAM) of kainate receptor (KAR) subunits GluK1b, GluK2a, and GluK3a, primarily used for research. It potentiates glutamate-evoked currents of GluK2a and significantly decreases desensitization kinetics. It also modulates AMPA receptor activity in primary neuron cell cultures.
Positive allosteric modulator of KAR subunits GluK1b, GluK2a, GluK3a
Potentiates glutamate-evoked currents of GluK2a (EC50 of 79 μM)
Decreases desensitization kinetics (5.5 to 775 ms)
Potentiates peak current amplitude of KAR and AMPA receptor subunits
Modulates AMPA receptor in rat embryonic cortex primary neuronal culture (EC50 of 0.9 μM)
Molecular weight: 242.27
Chemical formula: C10H11FN2O2S
Appearance: White to off-white solid
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P11 is a selective inhibitor of platelet-activating factor acetylhydrolases (PAFAHs) 1b2 and 1b3 that has been shown to impair cancer cell survival. It exhibits IC50 values of approximately 40 nM for PAFAH1b2 and 900 nM for PAFAH1b3.
Selective inhibitor of PAFAH1b2 and PAFAH1b3.
Impairs cancer cell survival.
High purity (99.69%).
Available in various quantities and as a 10 mM solution in DMSO.
Well-characterized with available data sheet, COA, and SDS.
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OS-2966 is a humanized antibody expressed in CHO cells targeting Integrin b1/ITGB1/CD29 OS-2966 carries a huIgG1 type heavy chain and a hu type light chain with a predicted molecular weight (MW) of 145 5 kDa The isotype control for OS-2966 can be referenced as Human IgG1 kappa Isotype Control (HY-P99001)
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Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Facilitates selective degradation of target proteins
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2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.
Steroid-based cationic lipid
Contains a 2H-cholesterol skeleton
Coupled to an L-arginine head group
Facilitates gene transfection
Stable under recommended storage conditions
For research use only
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