Kisspeptin 13 TFA is the TFA salt form of Kisspeptin 13 (HY-P3641). It inhibits glucose-induced insulin secretion with an IC50 of 1.2 nM. Kisspeptin 13 TFA activates the hypothalamic-pituitary-adrenal (HPA) axis, causes hyperthermia, motor behavior and anxiety in rats. This compound interacts with α2-adrenergic and 5-HT2 serotonin receptors and exhibits antidepressant efficacy. It is an activator for GPR54 and GnRH receptor, enhancing memory and being useful in Alzheimer's disease research.
- Inhibits glucose-induced insulin secretion (IC50 of 1.2 nM)
- Activates hypothalamic-pituitary-adrenal (HPA) axis
- Causes hyperthermia, motor behavior and anxiety in rats
- Interacts with α2-adrenergic and 5-HT2 serotonin receptors
- Exhibits antidepressant efficacy
- Activator for GPR54 and GnRH receptor
- Enhances memory
- Useful in Alzheimer's disease research