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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
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Demecarium bromide is a long-acting quaternary ammonium cholinesterase inhibitor used in research on glaucoma and cholinesterase activity. Supplied as the bromide salt, it has a reported apparent affinity (Kiapp) of approximately 0.15 μM and is provided with a product data sheet and SDS for safe handling.
Long-acting cholinesterase inhibitor for glaucoma research
Reported Kiapp ~0.15 μM against cholinesterase
High chemical purity (~95.0%) suitable for research use
Available in small quantities for laboratory experiments
Provided with a product data sheet and safety data sheet
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Chemical. CAS 155862-90-1. Formula C23H18BrN3O2S. MW 480.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Major disadvantage rel. low extinction coefficient.
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Valethamate bromide is an ester that acts as an effective, rapidly acting anticholinergic antispasmodic and muscle relaxant. It accelerates labor by improving cervical dilation, significantly shortening the labor process with fewer side effects.
Acts as an effective, rapidly acting anticholinergic antispasmodic and muscle relaxant
Accelerates labor by improving cervical dilation
Significantly shortens the labor process with fewer side effects
For research use only
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Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
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Ipratropium bromide hydrate is a muscarinic receptor antagonist that relaxes smooth muscle. It is used in research for conditions such as COPD and asthma, acting with high potency on M1, M2, and M3 receptors. This product is intended for research use only.
Muscarinic receptor antagonist
Relaxes smooth muscle
Effective in research for COPD and asthma
High potency on M1, M2, and M3 receptors
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Chemical. CAS 155863-03-9. Formula C29H24BrN3O6. MW 590.42. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance.
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N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
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Aclidinium Bromide is a long-acting, inhaled muscarinic antagonist. It is for research use only and has potential for chronic obstructive pulmonary disease (COPD) research. The product is not sold to patients and has not been fully validated for medical applications.
Long-acting muscarinic antagonist
Potential for chronic obstructive pulmonary disease (COPD) research
Sustained bronchodilation suggested by M3 and M2 receptor residence times
Low systemic bioavailability and favorable safety profile confirmed in studies
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N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog that primarily acts as a smooth muscle vasodilator. It has also been shown to inhibit cancer progression. This product is for research use only.
Appears as a solid with a color ranging from white to off-white
Molecular weight: 887.96
Primarily functions as a smooth muscle vasodilator
Demonstrated ability to inhibit cancer progression
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4-(2-Bromoacetyl)benzonitrile, also known as 4-Cyanophenacyl bromide, is a compound used in the synthesis of STA-5312, a potent and orally active microtubule inhibitor. This product is intended for research use only.
Can be utilized in the synthesis of STA-5312.
Appears as an off-white to yellow solid.
Store at 4°C, protected from light.
In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
Soluble in DMSO at 100 mg/mL.
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Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
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