Acyl Halides
Medchemexpress LLC Tiotropium Bromide | 136310-93-5 | 99.9% | 472.42 | 5 MG
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and the subsequent opening of the ligand-gated ion channel. This compound stops signaling between neurons, leading to muscle relaxation. It is also a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease and can improve symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
- mAChR antagonist
- Blocks binding of acetylcholine ligand
- Blocks subsequent opening of ligand-gated ion channel
- Long-acting, 24-hour anticholinergic bronchodilator
- Stops signaling between neurons
- Leads to muscle relaxation
- Used in the management of chronic obstructive pulmonary disease (COPD)
- Improves symptoms of COPD complicated by chronic heart failure
Apexbio Technology LLC Tiotropium Bromide 136310-93-5 10mM (in 1mL DMSO)
Tiotropium Bromide (CAS 136310-93-5) is a potent antagonist of muscarinic acetylcholine receptors (mAChRs) By competitively inhibiting acetylcholine binding at these receptors it prevents receptor activation and subsequent signaling cascades leading to decreased neuronal transmission and smooth muscle relaxation As a long-acting anticholinergic bronchodilator with activity lasting approximately 24 hours Tiotropium Bromide is widely studied in managing chronic obstructive pulmonary disease (COPD) including cases complicated by chronic heart failure
Apexbio Technology LLC Domiphen Bromide 538-71-6 10mM (in 1mL DMSO)
Domiphen bromide (CAS 538-71-6) is a small-molecule quaternary ammonium compound exhibiting antiseptic activity primarily through its function as a cationic surfactant Its positively charged molecular structure interacts with microbial membranes disrupting membrane integrity and leading to cell death Consequently it is widely studied for antimicrobial properties and applied in biological research as a surface-active disinfectant Domiphen bromide thus serves as a relevant tool compound in investigations focused on microbial control and antisepsis
Medchemexpress LLC Tiotropium (Bromide) | 136310-93-5 | 99.9% | 50 MG
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
- Long-acting, 24-hour, anticholinergic bronchodilator
- Used in the management of chronic obstructive pulmonary disease
- Improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure
- Stops signaling between neurons and leads to muscle relaxation
Medchemexpress LLC Roslin 2 bromide | 29574-21-8 | 99.0% | C13H19BrN4 | 1 MG
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that exhibits anticancer effects. It functions by binding to FAK, thereby disrupting the interaction between FAK and p53.
- Decreases cancer cell viability and clonogenicity in a p53-dependent manner.
- Increases p53 transcriptional activity, which is inhibited by FAK, using p21, Mdm-2, and Bax-promoter targets.
- Leads to increased expression of p53 targets: p21, Mdm-2, and Bax proteins.
- Significantly reduces tumor growth, disrupts the FAK and p53 complex, and up-regulates p21 in HCT116 p53+/+ xenografts (not in HCT116 p53-/- xenografts).
Medchemexpress LLC Tiotropium bromide | 136310-93-5 | 472.42 | 1 ML
Tiotropium bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. It is a 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. It improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
- Targets mAChR
- Involved in GPCR/G Protein and neuronal signaling pathways
- Long-acting, stops signaling between neurons and leads to muscle relaxation
- Used in the management of chronic obstructive pulmonary disease
- Improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure
Medchemexpress LLC Tiotropium (Bromide) | 136310-93-5 | 99.9% | 472.42 | 100 MG
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and the subsequent opening of the ligand-gated ion channel. It is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). It has also been shown to improve symptoms of COPD complicated by chronic heart failure.
- Muscarinic acetylcholine receptor (mAChR) antagonist
- Blocks binding of acetylcholine ligand and opening of ligand-gated ion channel
- Stops signaling between neurons leading to muscle relaxation
- Long-acting, 24-hour anticholinergic bronchodilator
- Used in the management of chronic obstructive pulmonary disease (COPD)
- Improves symptoms of COPD complicated by chronic heart failure
- For research use only