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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
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CCL4 Protein Human is a small cytokine of the CC chemokine subfamily that binds to the CCR5 chemokine receptor on the cell surface promotes leukocyte aggregation under various inflammatory conditions and contributes to immune protection against human immunodeficiency virus type 1 CCL4 Protein Human is a recombinant human CCL4 (A24-N92) expressed by E coli[1]
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2-Ethylbutyric acid is a volatile fatty acid known for its phytotoxicity. It serves as an internal standard in milk and dairy products, aids in calibrating fecal VFA standards, and is used in embryonic development research.
Exhibits acute phytotoxicity in seed germination bioassays.
Shows teratogenic activity in pregnant mice at 600 mg/kg (s.c.; single dose).
No developmental toxicity in pregnant Sprague-Dawley rats at 150-200 mg/kg (p.o.; once daily; gestation days 6 to 15), with a No Observed Adverse Effect Level (NOAEL) of 200 mg/kg.
EC50 of 33.74 μM for reduction of propionyl-CoA in human hepatocytes.
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360A iodide (CAS 737763-37-0) is a 2 6-pyridine-dicarboxamide derivative that acts as a selective ligand for G-quadruplex DNA structures By stabilizing telomeric G-quadruplexes 360A inhibits telomerase activity and induces alterations in cell cycle progression notably causing S-phase accumulation in ATM-proficient EBV-lymphocytes Its mechanism of action involves promoting sister telomere fusions via DNA-PKcs-dependent non-homologous end joining (NHEJ) as well as triggering NHEJ and homologous recombination (HR) pathways at telomeres which disrupt mitotic progression 360A has been shown to preferentially bind telomeric G-quadruplex DNA over duplex DNA and to delay growth in HT1080 tumor cells This compound is valuable for investigating telomere biology DNA damage response and G-quadruplex-mediated genomic stability
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(-)-Alkannin is a naturally occurring naphthoquinone used in research as an apoptosis inducer that can arrest the cell cycle. It is supplied as a high-purity solid suitable for biochemical and cell-based studies, provided in small packaging for limited-scale experiments.
Apoptosis inducer and cell cycle arrest agent.
High purity suitable for analytical and biological assays.
Solid, brown to red appearance for easy handling.
Available in small package sizes (including 10 mg) for pilot studies.
Recommended storage conditions provided for powder and solutions.
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