Alkyl Halides
Matrix Scientific 4-BROMO-1-BUTENE-25G
4-Bromo-1-butene, 98%; 25g,C4H7Br, MFCD00000258, mw 135.01, [5162-44-7]
TARGETMOL CHEMICALS INC BAY-678 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BAY-678 is a human neutrophil elastase (HNE; IC50 20 nM) inhibitor with oral bioactivity potency and selectivity.BAY-678 is a chemical probe recommended by the Structural Genomics Consortium (SGC). purity: 98%
Medchemexpress LLC BAY-678 | 675103-36-3 | 99.6% | 400.35 | 1 ML
BAY-678 is an orally bioavailable, highly potent, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC₅₀ of 20 nM. It has been nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). It demonstrates significant efficacy in preclinical models of ALI and lung emphysema, showing anti-inflammatory and anti-remodeling actions. Additionally, it has shown beneficial pulmonary hemodynamic and vascular effects in models of PAH in rats and mice.
- Orally bioavailable and cell-permeable inhibitor of human neutrophil elastase
- Exhibits more than 2,000-fold selectivity in a panel of 21 serine proteases
- Shows significant efficacy in preclinical models of ALI and lung emphysema
- Demonstrates anti-inflammatory and anti-remodeling modes of action
- Beneficial pulmonary hemodynamic and vascular effects in models of PAH
Medchemexpress LLC 2-Pyridinecarbonitrile, 5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]- | 675103-36-3 | 99.6% | 400.35 | 25 MG
2-Pyridinecarbonitrile, 5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]- | 675103-36-3 | 99.6% | 400.35 | 25 MG
Medchemexpress LLC LMP2A (426-434) | 152274-91-4 | 96.1% | 906.16 | 10 MG
LMP2A (426-434) | 152274-91-4 | 96.1% | 906.16 | 10 MG
Medchemexpress LLC Perfluoropentanoic acid (PFPeA) | 2706-90-3 | 98.0% | 264.05 | 100 G
Perfluoropentanoic acid (PFPeA) | 2706-90-3 | 98.0% | 264.05 | 100 G
TARGETMOL CHEMICALS INC X-376 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration X-396 binds to and inhibits ALK kinase ALK fusion proteins and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development. purity: 98%