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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
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Bromo-PEG3-bromide is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Enables selective degradation of target proteins
Utilizes intracellular ubiquitin-proteasome system
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Allyl (11S 11aS)-11-((tert-butyldimethylsilyl)oxy)-8-hydroxy-7-methoxy-2-methyl-5-oxo-11 11a-dihydro-1H-benzo[e]pyrrolo[1 2-a][1 4]diazepine-10(5H)-carboxylate is a drug intermediate for synthesis of various active compounds
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Vilagletistat (ZED-1227) is a small-molecule, orally active transglutaminase 2 (TG2) inhibitor supplied for research use. It is provided as a high-purity powder in multiple package sizes and includes storage and stability guidance for powder and solutions.
High purity: reported 99.82% typical; example batch 99.97%.
CAS number 1542132-88-6.
Molecular formula C26H36N6O6 and molecular weight 528.60 g·mol^-1.
Available package sizes from 1 mg to 100 mg; larger quantities available by quote.
Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
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