Benzenoids
eMolecules 3-(2-METHOXYPHENOXY)BENZYLAMINE HCL | 1171099-72-1 | MFCD03840102 | 1g
AstaTech | 3-(2-METHOXYPHENOXY)BENZYLAMINE HCL | 1g | 112531074 | AR1571 | 95.000 | 1171099-72-1 | MFCD03840102 | 265.740 | C14H16ClNO2
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eMolecules TRIOCTANOIN | 538-23-8 | MFCD00036236 | 25g
AstaTech | TRIOCTANOIN | 25g | 571814652 | A11562 | 95.000 | 538-23-8 | MFCD00036236 | 470.691 | C27H50O6
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Selleck Chemical LLC Verubulin hydrochloride S3374-5mg
Verubulin hydrochloride(MPC 6827 hydrochloride) is a microtubule destabilizer and vascular disrupting agent that achieve high brain concentration relative to plasma in animals
eMolecules 3-(Benzyloxy)-5-chlorobenzaldehyde | 1228956-94-2 | MFCD16618949 | 1g
Combi-Blocks | 3-(Benzyloxy)-5-chlorobenzaldehyde | 1g | 117528746 | CA-5003 | 96.000 | 1228956-94-2 | MFCD16618949 | 246.690 | C14H11ClO2
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Selleck Chemical LLC Skp2 inhibitor C1
Skp2 inhibitor C1 (SKPin C1) is a specific and selective small-molecule inhibitor of Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts
Selleck Chemical LLC Eliprodil
Eliprodil (SL-820715) is a non-competitive NR2B-selective NMDA antagonist with IC50 value of 1 M and is less potent for NR2A- and NR2C-containing receptors with IC50 100 M
Apexbio Technology LLC Difloxacin HCl 91296-86-5 5g
Difloxacin HCl (CAS 91296-86-5) is a small-molecule inhibitor targeting DNA gyrase and topoisomerase IV It is designed to interfere with DNA gyrase-mediated DNA synthesis thereby inhibiting bacterial DNA replication and cell division Difloxacin HCl exerts its biological activity primarily through inhibition of DNA gyrase and topoisomerase IV In cultured human neuroblastoma cells exhibiting multidrug resistance associated protein (MRP)-mediated chemoresistance difloxacin HCl (50 g/ml) increases cell sensitivity to MRP substrates including doxorubicin vincristine daunorubicin and potassium antimony tartrate indicating reversal of the drug-resistance phenotype Based on these pharmacological properties difloxacin HCl holds research potential in antimicrobial susceptibility testing and studies of multidrug resistance reversal
Medchemexpress LLC C-82 | 1422253-37-9 | 99.9% | 578.66 | 1 MG
C-82 is a second-generation specific CBP/β-catenin antagonist. It functions by inhibiting the binding between β-catenin and CBP, while simultaneously increasing the binding between β-catenin and p300. C-82 is the active form of PRI-724, which is rapidly hydrolyzed to C-82 in vivo and has shown an acceptable toxicity profile in preclinical studies.
- Inhibits CBP/β-catenin binding.
- Increases β-catenin/p300 binding.
- Inhibits activation of quiescent hepatic stellate cells (HSCs).
- Promotes cell death in culture-activated HSCs.
Apexbio Technology LLC BI 6015 93987-29-2 10mg
BI 6015 is a small-molecule antagonist targeting hepatocyte nuclear factor 4 alpha (HNF4 ) a nuclear receptor implicated in transcriptional regulation within liver intestinal and pancreatic -cells It is designed to inhibit HNF4 -mediated transcriptional activation thereby modulating gene expression related to glucose and lipid metabolism BI 6015 exerts its biological activity primarily through direct antagonism of HNF4 leading to reduced transcriptional activation and lowering endogenous HNF4 protein levels In cell-based studies BI 6015 demonstrates inhibition of insulin promoter activity and suppression of endogenous insulin expression in T6PNE cells as well as decreased HNF4 protein in MIN6 and HepG2 cells Based on these pharmacological properties BI 6015 holds research potential in the study of diabetes and hepatic metabolic regulation
eMolecules 2-AMINO-3-(TRIFLUOROMETHYL)-BENZALDEHYDE | 1288999-00-7 | MFCD24645192 | 1g
AstaTech | 2-AMINO-3-(TRIFLUOROMETHYL)-BENZALDEHYDE | 1g | 487923091 | F15872 | 97.000 | 1288999-00-7 | MFCD24645192 | 189.137 | C8H6F3NO
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eMolecules 3-BROMO-4-CHLORO-1,6-NAPHTHYRIDINE | 53454-36-7 | MFCD28970475 | 0.1g
AstaTech | 3-BROMO-4-CHLORO-1,6-NAPHTHYRIDINE | 0.1g | 512030631 | F13544 | 95.000 | 53454-36-7 | MFCD28970475 | 243.490 | C8H4BrClN2
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eMolecules 1-(2-AMINO-5-BROMOPHENYL)PROPAN-1-ONE | 124623-15-0 | MFCD14582820 | 1g
AstaTech | 1-(2-AMINO-5-BROMOPHENYL)PROPAN-1-ONE | 1g | 532624316 | C14451 | 95.000 | 124623-15-0 | MFCD14582820 | 228.089 | C9H10BrNO
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Medchemexpress LLC Dicamba | 1918-00-9 | 100.0% | 25 G
Dicamba is a chlorinated benzoic acid herbicide supplied as a high-purity small-molecule research reagent used in agricultural and environmental studies. It is provided with lot-specific quality and safety documentation for laboratory use.
- Chlorinated benzoic acid (C8H6Cl2O3) with CAS 1918-00-9.
- High purity suitable for analytical and research use.
- Available in multiple pack sizes including 25 G for small-scale studies.
- Supplied with COA and SDS for lot-specific quality and safety information.
- Useful as a reference standard in herbicide research and environmental testing.
Apexbio Technology LLC BI-847325 1207293-36-4 10mg
BI-847325 (CAS 1207293-36-4) is a dual inhibitor targeting MEK1/2 and Aurora kinases with reported IC50 values of 25 nM and 4 nM against MEK1 and MEK2 and 3 nM 25 nM and 15 nM against Aurora A B and C respectively By inhibiting these kinases BI-847325 disrupts the MAPK/ERK and cell cycle signaling pathways that regulate cell proliferation and survival In cellular assays it demonstrates nanomolar EC50 values for inhibition of pERK and pHH3 in KRAS- and BRAF-mutant cancer cell lines and potently suppresses proliferation across a wide range of tumor cell models In xenograft studies it fully blocks tumor growth in BRAF- and KRAS-mutant cancer models This compound is utilized in research on kinase-targeted cancer therapies
Apexbio Technology LLC STA-21 111540-00-2 1mg
STA-21 (CAS 111540-00-2) is a small-molecule inhibitor targeting STAT3 a transcription factor activated by cytokines such as IL-6 It inhibits STAT3 DNA-binding activity and dimerization thereby modulating downstream signaling pathways associated with Th17 differentiation and inflammatory processes STA-21 exerts its biological activity primarily by suppressing STAT3-mediated IL-17 expression and osteoclast differentiation as well as promoting FoxP3 expression In in vitro studies STA-21 inhibits DU145 cell viability with an IC50 of 12 2 M Based on these pharmacological properties STA-21 holds research potential in the fields of autoimmune and inflammatory disease