Benzenoids
Medchemexpress LLC Bis(pinacolato)diborane | 73183-34-3 | 99.97% | C12H24B2O4 | 100 G
Bis(pinacolato)diborane is an organoboron reagent. It functions as a source of the [Bpin] moiety, which exhibits a pronounced nucleophilic character. This makes it valuable in the synthesis of various organoboranes, including organoboron compounds and arylboronates. Additionally, Bis(pinacolato)diborane is known to react with p-benzyne, leading to the production of tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group.
- Organoboron reagent
- Source of nucleophilic [Bpin] moiety
- Used in the synthesis of various organoboranes, including organoboron compounds and arylboronates
- Reacts with p-benzyne to produce tetraborylated products
Medchemexpress LLC Methyl 3-hydroxybenzoate | 19438-10-9 | 99.6% | C8H8O3 | 100 G
Methyl 3-hydroxybenzoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. This compound is characterized as a bioactive chemical. It is strictly for research use only and is not intended for sale to patients.
- Biochemical reagent
- Utilized as a biological material
- Used as an organic compound
- Suitable for life science-related research applications
- Bioactive chemical
Medchemexpress LLC Bosentan | 147536-97-8 | 99.9% | C27H29N5O6S | 100 MG
Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors. It features a high purity of 99.9% and is used in various research applications. It is supplied as a solid.
- Competitive and dual antagonist of endothelin-1 (ET)
- Targets ETA and ETB receptors
- Ki values of 4.7 nM and 95 nM in human SMC for ETA and ETB receptors
- Soluble in DMSO
Apexbio Technology LLC CPI-637 1884712-47-3 50mg
CPI-637 (CAS 1884712-47-3) is a selective small molecule inhibitor targeting the bromodomains of CBP (CREB-binding protein) and EP300 with IC50 values of 0 03 M and 11 0 M respectively It demonstrates over 700-fold selectivity for CBP/EP300 bromodomains relative to the BET bromodomain family and displays significant selectivity over other bromodomain-containing proteins with notable biochemical activity observed only against BRD9 In cellular assays CPI-637 inhibits MYC expression with an EC50 of 0 60 M and effectively engages CBP in BRET assays (EC50 0 3 M) CPI-637 is currently utilized in preclinical research to investigate the role of CBP/EP300 bromodomains in transcriptional regulation and disease pathways
Selleck Chemical LLC IU1-47
IU1-47 is a potent and specific inhibitor of USP14 with an IC50 of 0 6 M IU1-47 shows 33-fold selectivity for USP14 over USP5 (IsoT)
Selleck Chemical LLC DTT
DTT (Dithiothreitol) a small-molecule redox reagent is a standard agent for reducing disulfide bonds between and within biological molecules Solutions are best fresh-prepared
Medchemexpress LLC Disodium cantharidin | 1465-77-6 | 95.0% | 258.18 g·mol⁻1 | C10H12Na2O5 | 5 MG
Disodium cantharidin is the disodium salt of cantharidin and functions as a selective inhibitor of protein phosphatases PP2A and PP1. Supplied as a solid research reagent (5 mg), it is used in biochemical and cell-based studies to probe phosphatase activity, cell signaling, and apoptosis. For research use only.
- Selective PP2A and PP1 inhibitor, useful for signaling studies.
- Reported activity: PP2A IC50 ≈ 50 nM, PP1 IC50 ≈ 600 nM.
- High purity solid, typically 95% by vendor specification.
- Small package sizes suitable for screening and method development.
- Sodium salt form with formula C10H12Na2O5 and molecular weight 258.18 g·mol⁻1.
Medchemexpress LLC MRTX849 acid | 2561529-96-0 | MFCD00868113 | 99.8% | 662.15 | C34H37ClFN7O4 | 5 MG
MRTX849 acid is the carboxylic acid derivative of MRTX849 used as a ligand or synthetic intermediate in KRAS G12C research and PROTAC preparation. It is supplied as a high-purity, light yellow solid with molecular formula C34H37ClFN7O4 and molecular weight 662.15. Store at -20°C and protect from light; in solution, store at -80°C for long-term or -20°C for short-term.
- High purity suitable for research applications.
- Light yellow solid facilitating handling.
- Useful as a ligand or intermediate for KRAS G12C and PROTAC synthesis.
- Stable when stored at -20°C and protected from light.
- Storage recommendations provided for neat material and solutions.