Benzenoids
Medchemexpress LLC Valacyclovir (hydrochloride) | 124832-27-5 | 99.9% | 360.80 | 25 MG
Valacyclovir hydrochloride is an orally active antiviral agent effective against herpes simplex, herpes zoster, and herpes B. It acts as a proagent of Aciclovir, inhibiting HSV-1. Its uptake is concentration dependent and saturable, suggesting hPEPT1 dominates its intestinal transport in vitro. Clinical trials show its effectiveness in treating genital herpes and recurrences, with a 1 g daily dose being as effective as 2 g daily.
- Orally active antiviral agent
- Effective against herpes simplex, herpes zoster, and herpes B
- Inhibits HSV-1 with an IC50 of 2.9 μg/ml
- Proagent of Aciclovir
- Uptake is concentration dependent and saturable
- Effective for treating genital herpes and recurrences
- Daily dose of 1 g is as effective as 2 g daily
Medchemexpress LLC HY-U00248A 1mg Medchemexpress, LMP744 hydrochloride CAS:308246-57-3 Purity:>98%
Medchemexpress, HY-U00248A 1mg LMP744 hydrochloride CAS:308246-57-3 LMP744 hydrochloride (MJ-III65 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC phospho-PI3 Kinase p110 beta (Ser1070) Antibody | 100 UL
This antibody is a rabbit-derived, non-conjugated IgG polyclonal antibody. It specifically targets phospho-PI3 Kinase p110 beta (Ser1070) and is intended for research use only, not for diagnostic or therapeutic use.
- Molecular weight: Predicted 110-123 kDa, observed 110 kDa
- Species reactivity: Human, mouse, rat (predicted: chicken, dog, pig, cow, horse, guinea pig)
- Affinity purified
- Non-conjugated
- Phosphorylated modification
- Isotype: IgG
- Formulation: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Storage: -20°C for 1 year; avoid repeated freeze/thaw cycles
- Shipping: With blue ice
- Applications: WB (1:500-2000), IHC-P/F (1:100-500), ICC/IF (1:100-500)
- Endogenous sensitivity
- Immunogen: KLH conjugated phosphopeptide from human PI3 Kinase p110 beta around Ser1070
- SwissProt ID: P42338
- Gene ID: 5291
eMolecules Medchem Express / BMS-191011 / 5mg / 455325958 / HY-108593 / / 202821-81-6 / MFCD09753285 / 370.710 / C16H10ClF3N2O3
Medchem Express / BMS-191011 / 5mg / 455325958 / HY-108593 / / 202821-81-6 / MFCD09753285 / 370.710 / C16H10ClF3N2O3
Medchemexpress LLC Sorbic acid | 110-44-1 | 112.13 | 500 G
Sorbic acid is an effective, safe, and non-toxic food preservative that can inhibit most molds, yeasts, and certain bacteria. It is orally active and can enhance the growth performance of economically important animals by activating the insulin-like growth factor system (IGF). It can also lead to lipid accumulation by disrupting lipid clearance pathways.
- Effective, safe, and non-toxic food preservative.
- Inhibits most molds, yeasts, and certain bacteria.
- Orally active.
- Can enhance growth performance in certain animals by activating the IGF system.
- Can lead to lipid accumulation by disrupting lipid clearance pathways.
- Purity: 99.99%.
- Appearance: Solid.
- Color: White to off-white.
- Structure classification: Ketones, aldehydes, acids.
- Initial source: Plants other families, microorganisms, endogenous metabolite.
Medchemexpress LLC Cis-benzyl 3-hydroxycyclobutylcarbamate | 1403766-86-8 | MFCD23106304 | 221.26 g/mol | C12H15NO3 | 50 G
cis-Benzyl 3-hydroxycyclobutylcarbamate is a small-molecule drug intermediate used in medicinal chemistry for the synthesis of active pharmaceutical compounds. It has molecular formula C12H15NO3 and molecular weight 221.26 g/mol. Handle according to the safety data sheet: harmful if swallowed, store sealed and protected from moisture at 4°C.
- Used as a synthetic intermediate in medicinal chemistry
- Molecular formula C12H15NO3
- Molecular weight 221.26 g/mol
- Recommended storage: 4°C, sealed, away from moisture
- Hazard: harmful if swallowed (GHS acute toxicity category 4); follow SDS precautions
Cambridge Isotope Laboratories 2 4 6-Tribromoanisole (unlabeled) 100 ug/mL in toluene 1 2 mL
2 4 6-Tribromoanisole (unlabeled) 100 ug/mL in toluene 1 2 mL
Medchemexpress LLC Carnosic acid | 3650-09-7 | 332.43 | 50 MG
Carnosic acid (Standard) is an analytical standard used for research and analytical applications. It exhibits inhibition of oxidative stress and inflammation, suppresses cell proliferation, and demonstrates antibacterial activity. This reference standard is widely utilized in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- Purity: 98.43%
- Appearance: Solid
- Color: Light yellow to yellow
- Structure classification: Terpenoids, Diterpenoids, Phenols, Polyphenols
- Initial source: Plants Leguminosae Paramacrolobium coeruleum (Taub.) J.Léonard, Plants Labiatae
eMolecules 2-Benzylaminopropanol | 3217-09-2 | MFCD00021997 | 100mg
Apollo Scientific | 2-Benzylaminopropanol | 100mg | 562465426 | OR510057 | 97.000 | 3217-09-2 | MFCD00021997 | 165.236 | C10H15NO
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Apexbio Technology LLC TUG-770 1402601-82-4 50mg
TUG-770 (CAS 1402601-82-4) is a potent agonist of the free fatty acid receptor 1 (FFA1/GPR40) a G protein-coupled receptor implicated in the enhancement of glucose-stimulated insulin secretion by pancreatic -cells TUG-770 demonstrates high affinity for FFA1 with an EC50 of 6 nM and over 150-fold selectivity compared to FFA4 as well as high selectivity over other receptors and transporters In INS-1E rat -cell lines TUG-770 promotes insulin secretion in the presence of elevated glucose Pharmacokinetic studies in mice indicate favorable oral absorption and bioavailability with dose-dependent reductions in blood glucose during glucose tolerance tests TUG-770 is a valuable tool for investigating FFA1-mediated pathways and glucose homeostasis in metabolic research
Medchemexpress LLC IITZ-01 | 1807988-47-1 | 98.18% | 482.51 | 1 ML
IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ. For research use only.
- Potent lysosomotropic autophagy inhibitor.
- Single-agent antitumor activity.
- IC50 of 2.62 μM for PI3Kγ.
- Enhances autophagosomes formation in triple-negative breast cancer (TNBC) cell lines (MDA-MB-231 and MDA-MB-453) by increasing LC3-II levels time- and dose-dependently.
- Demonstrates potent autophagy inhibitory activity in other breast, lung, and colon cancer cells.
- Inhibits average breast tumor growth in triple-negative breast tumor models in mice.