Benzenoids
Medchemexpress LLC 3-Methylazetidin-3-ol hydrochloride | 124668-46-8 | ≥97.0% | C4H10ClNO | 10 G
3-Methylazetidin-3-ol hydrochloride is a drug intermediate for the synthesis of various active compounds. This product is for research use only and is not sold to patients.
- Drug intermediate
- Used for synthesis of active compounds
- For research use only
Medchemexpress LLC Gol-NTR | 2968461-58-5 | C24H16F3N3O4 | 5 MG
Gol-NTR is a Golgi-targetable probe characterized by its high selectivity and sensitivity. It is activated by Nitroreductase (NTR) and is capable of visualizing acute lung injury (ALI) as well as its repair function. The probe exhibits a low detection limit of 54.8 ng/mL, making it suitable for research focused on monitoring and assessing the response to sepsis-induced ALI.
- High selectivity and sensitivity
- Golgi-targetable
- Nitroreductase (NTR)-activated
- Capable of visualizing acute lung injury (ALI)
- Capable of visualizing ALI repair function
- Low detection limit of 54.8 ng/mL
- Suitable for monitoring and assessing response to sepsis-induced ALI
eMolecules N,N-Dimethyl 3-borono-4-methylbenzenesulfonamide | 871332-99-9 | 1G | Purity: 98%
Combi-Blocks | N,N-Dimethyl 3-borono-4-methylbenzenesulfonamide | 1G | 871332-99-9 | MFCD08056363
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Medchemexpress LLC Olpasiran sodium | 2225856-03-9 | C490H610F11N164Na42O306P41S7 | 1 MG
Olpasiran sodium is an N-acetyl galactosamine (GalNAc)-conjugated, hepatocyte-targeted siRNA. It directly inhibits LPA messenger RNA translation in hepatocytes and potently reduces Lp(a) concentration. It can be used for the research of cardiovascular disease, such as atherosclerosis.
- N-acetyl galactosamine (GalNAc)-conjugated, hepatocyte-targeted small interfering RNA.
- Potently reduces lipoprotein(a) concentration by directly inhibiting LPA messenger RNA translation.
- Demonstrated efficacy in silencing LPA reporter gene expression in human hepatocellular carcinoma cells.
- Achieves sustained and significant reductions in serum lipoprotein(a) levels in preclinical animal models.
- Potential application in cardiovascular disease research, specifically atherosclerosis.
Medchemexpress LLC R-NVS-ZP7-4 50mg | 2517682-14-1 | 50 MG
(R)-NVS-ZP7-4 is the R-enantiomer of NVS-ZP7-4, a small-molecule inhibitor of the zinc transporter SLC39A7 (ZIP7) supplied as an optically pure research compound for biochemical and cellular studies targeting ER zinc homeostasis, Notch signaling, and ferroptosis-related pathways.
- Optically pure R-enantiomer for stereochemistry-specific studies.
- High purity (~98.8%) suitable for biochemical and cellular assays.
- Solid, light yellow to yellow form; stable when stored at -20°C.
- Solvent storage: -80°C for up to 6 months, -20°C for up to 1 month (protect from light).
- Useful for probing ZIP7 function, ER zinc levels, Notch signaling, and ferroptosis mechanisms.
eMolecules 4-BIPHENYL-4'-FLUORO-CARBOXYLIC ACID | 5731-10-2 | 5G | Purity: 98%
AstaTech | 4-BIPHENYL-4'-FLUORO-CARBOXYLIC ACID | 5G | MFCD01631909
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Medchemexpress LLC GsMTx4 TFA | 99.9% | 4095.84 (free base) | 5 MG
GsMTx4 TFA is a spider venom peptide designed to selectively inhibit cationic-permeable mechanosensitive channels (MSCs) within the Piezo and TRP channel families. It acts as a pharmacological tool to investigate the role of these excitatory MSCs in both normal physiological processes and various pathological conditions.
- Selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to Piezo and TRP families.
- Blocks cation-selective stretch-activated channels in various cell types.
- Attenuates lysophosphatidylcholine-induced astrocyte toxicity and microglial reactivity.
- Neuroprotective in the cerebral cortex.
- Reduces mechanical allodynia in models of inflammation and sciatic nerve injury.
Chemscene ChemScene | (4-Fluoro-2-(trifluoromethyl)phenyl)methanamine | 5G | CS-W015787 | 0.98 | 202522-22-3| MFCD00061164 | 193.14
ChemScene | (4-Fluoro-2-(trifluoromethyl)phenyl)methanamine | 5G | CS-W015787 | 0.98 | 202522-22-3| MFCD00061164 | 193.14
Chemscene ChemScene | 4-Chloro-3-(trifluoromethyl)phenylacetic acid | 1G | CS-W022145 | 0.98 | 22902-86-9| MFCD04116012 | 238.59
ChemScene | 4-Chloro-3-(trifluoromethyl)phenylacetic acid | 1G | CS-W022145 | 0.98 | 22902-86-9| MFCD04116012 | 238.59
Selleck Chemical LLC LXR-623
LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR- and LXR- respectively It is orally bioavailable and readily passes the blood-brain barrier