Benzenoids
Medchemexpress LLC Gabapentin hydrochloride | 60142-95-2 | 98.0% | C9H18ClNO2 | 1 ML
Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. It inhibits neuronal Ca2+ influx and reduces neurotransmitter release. This GABA analog can be used to relieve neuropathic pain.
- Potent, orally active P/Q type Ca2+ channel blocker
- Inhibits neuronal Ca2+ influx
- Reduces neurotransmitter release
- GABA analog for neuropathic pain relief
- Improves spatial and emotional cognitive performance (in mice)
- Exhibits analgesic effect and reduces writhing (in mice)
Apexbio Technology LLC PTP Inhibitor I 2491-38-5 10mM (in 1mL DMSO)
PTP Inhibitor I (CAS 2491-38-5) is a small molecule inhibitor targeting protein tyrosine phosphatases (PTPs) specifically SHP-1 and PTP1B with inhibition constants (KI) of 43 M and 42 M respectively As an -bromoacetophenone derivative it acts as a neutral phosphotyrosine mimetic covalently modifying the active site cysteine of PTPs Structure-activity studies indicate that modifications to the phenyl ring moderately affect potency while para-substituted peptidyl groups can enhance both potency and selectivity PTP Inhibitor I is utilized in vitro for mechanistic studies of PTP function related to diabetes neurodegenerative disorders immune regulation and pathogen virulence Animal and clinical data are not available
Medchemexpress LLC Dextran T70 (MW 70,000) | 9004-54-0 | 64000-76000 | 25 G
Dextran T70 (MW 70,000) | 9004-54-0 | 64000-76000 | 25 G
Medchemexpress LLC Glimepiride | 93479-97-1 | MFCD00878417 | 99.92% | C24H34N4O5S | 1 G
Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound. It lowers blood glucose more effectively than glibenclamide and is generally associated with a lower risk of hypoglycemia and less weight gain compared to other sulfonylureas. Its use may be safer for patients with cardiovascular disease due to its lack of detrimental effects on ischemic preconditioning.
- Lowers blood glucose more effectively than glibenclamide.
- Decreases extracellular Aβ40 and Aβ42 levels.
- Associated with lower risk of hypoglycemia.
- Associated with less weight gain compared to other sulfonylureas.
- May be safer for patients with cardiovascular disease.
Medchemexpress LLC Talipexole dihydrochloride | 36085-73-1 | MFCD00274573 | 99.8% | C10H17Cl2N3S | 100 MG
Talipexole dihydrochloride is a potent dopamine D2 receptor agonist, alpha2-adrenoceptor agonist, and 5-HT3 receptor antagonist. It exhibits significant anti-Parkinsonian activity and is exclusively intended for research applications.
- Acts as a dopamine D2 receptor agonist
- Functions as an alpha2-adrenoceptor agonist
- Serves as a 5-HT3 receptor antagonist
- Exhibits anti-Parkinsonian activity
- Suitable for in vitro and in vivo research
- D2 receptor IC50 value of 25 nM
- Demonstrated effects on blood pressure and heart rate in feline models
- Facilitates vagally mediated reflex bradycardia in canine models
Medchemexpress LLC Erinacin A | 156101-08-5 | 100.0% | 432.55 | 1 MG
Erinacin A | 156101-08-5 | 100.0% | 432.55 | 1 MG
Selleck Chemical LLC Anacardic Acid
Anacardic Acid (6-pentadecylsalicylic Acid) is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases which also has antibacterial activity antimicrobial activity prostaglandin synthase inhibition and tyrosinase and lipoxygenase inhibition
Medchemexpress LLC Ondansetron hydrochloride (GR 38032 hydrochloride) | 99614-01-4 | 99.4% | 50 MG
Ondansetron hydrochloride is a highly selective 5-HT3 receptor antagonist that inhibits nausea and vomiting induced by chemotherapy and radiotherapy. It acts by antagonizing 5-HT receptors in the peripheral and central nervous systems. This product is for research use only.
- Highly selective 5-HT3 receptor antagonist
- Inhibits nausea and vomiting caused by chemotherapy and radiotherapy
- Exerts antiemetic effect through 5-HT receptor antagonism
- Reduces EAAT3 response to L-glutamate in vitro
- Exhibits anti-inflammatory effects in vivo
- Purity of 99.4%
Medchemexpress LLC Madecassic acid | 18449-41-7 | 99.8% | 504.70 | 10 MG
Madecassic acid is a compound isolated from Centella asiatica (Umbelliferae). It demonstrates anti-inflammatory properties by inhibiting various inflammatory mediators through the downregulation of NF-κB activation in RAW 264.7 macrophage cells.
- Isolated from Centella asiatica
- Exhibits anti-inflammatory properties
- Inhibits iNOS and COX-2 protein expression
- Downregulates NF-κB activation
- Reduces IL-17 levels and γδT17 cells in colitis models
- For research use only
TARGETMOL CHEMICALS INC Ibotenic acid 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Ibotenic acid (RS-42358-197) has agonist activity at both the NMDA and trans-ACPD or metabotropic quisqualate receptors. Purity 99.7%