Benzenoids
Medchemexpress LLC 4-Amino-2-fluorobenzoic acid | 446-31-1 | 155.13 | 10 G
4-Amino-2-fluorobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is for research use only.
- Biochemical reagent for life science research
- Molecular weight of 155.13
- CAS number 446-31-1
- Appears as a solid
- Color is light brown to yellow
- Purity of 99.9%
- Stable under recommended storage conditions
Cayman Chemical Garcinol Natural Products Extr
A polyisoprenylated benzophenone with diverse biological activities; inhibits p300, PCAF, COX-1, mPGES-1, and 5-LO (IC50s = ~7, ~5, 12, 0.1, and 0.3 µM, respectively); active against C. neoformans in vitro at 0.8 µM; scavenges hydroxyl radicals and superoxide anions in cell-free assays; induces neurite outgrowth of primary embryonic rat neural progenitor cells at 5 µM; reduces ulcer area in rat models of gastric ulcers induced by water immersion stress or indomethacin at 200 mg/kg
Accela Chembio Inc 2-bromo-4-chloro-1-fluorobenzene | 100g | 1996-30-1 | MFCD00672934 | 97+% | D: 1.719 | Shelf Life: 1260 Days | Light Sensitive
2-bromo-4-chloro-1-fluorobenzene | 100g | 1996-30-1 | MFCD00672934 | 97+% | D: 1.719 | Shelf Life: 1260 Days | Light Sensitive
Apexbio Technology LLC ALC-0159 100mg
ALC-0159 is a polyethylene glycol (PEG)-modified lipid compound utilized as a component of lipid nanoparticles (LNP) for mRNA vaccine delivery systems Its primary function is to reduce interactions between lipid particles and plasma proteins through steric hindrance provided by PEG chains thus prolonging particle circulation time in vivo maintaining stability of drug-loaded particles in biological fluids and enhancing the efficiency of mRNA delivery into cells Currently it is widely applied in pharmaceutical formulations and biopharmaceutical research related to nucleic acid vaccines and delivery systems
Apexbio Technology LLC Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium 168555-66-6 10mM (in 1mL DMSO)
Fosbretabulin (Combretastatin A4 Phosphate CA4P) Disodium (CAS 168555-66-6) is a water-soluble prodrug of combretastatin A4 that acts as a microtubule-destabilizing agent and tumor vascular targeting compound By binding to tubulin CA4P disrupts microtubule dynamics leading to endothelial cell cytoskeletal rearrangement impaired proliferation and migration In vitro CA4P induces myosin light chain phosphorylation actin stress fiber assembly and focal adhesion formation in endothelial cells resulting in vascular shutdown at sub-maximal tolerated doses In vivo studies show significant reduction of tumor functional vasculature and increased tumor necrosis supporting its application in tumor angiogenesis and vascular research
Apexbio Technology LLC NPS-1034 1221713-92-3 100mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Medchemexpress LLC DMNB | 20357-25-9 | 100.0% | 211.17 | C9H9NO5 | 25 G
DMNB (6-nitroveratraldehyde) is a high-purity chemical intermediate used as a precursor in radiochemical synthesis, notably for preparing no-carrier-added 6-[18F]fluoro-L-DOPA for PET studies. The solid reagent is provided with analytical documentation and recommended storage to preserve stability for research applications.
- High purity: 99.98% (HPLC).
- Chemical formula C9H9NO5 and molecular weight 211.17.
- Used as a precursor for synthesis of no-carrier-added 6-[18F]fluoro-L-DOPA.
- Storage: store at 4°C under inert atmosphere; in solvent: -80°C (6 months), -20°C (1 month).
- Supplied with a certificate of analysis and safety data sheet.
TARGETMOL CHEMICALS INC Artemisic acid 100MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. 1. Artemisic acid ((+)-Artemisinic Acid) shows antibacterial activity. 2. Artemisinic acid is a major precursor of artemisinin (an antimalaric compound), isolated as the active principles of the medicinal plant Artemisia annua L. Purity 99.05%
Apexbio Technology LLC 3-Hydroxypicolinic acid 874-24-8 1g
3-Hydroxypicolinic acid (CAS 874-24-8) is a pyridine-based small molecule characterized by its capacity to chelate metal ions particularly copper(II) This ligand is commonly employed in the synthesis of metal coordination complexes which have been investigated for their ability to modulate biological activity through interactions involving metal ions and biomolecules Studies on such complexes indicate potential anti-tuberculosis properties attributed to their influence on metal-mediated biochemical pathways 3-Hydroxypicolinic acid is thus of interest in the fields of coordination chemistry and drug discovery supporting research into the bioactivity and molecular mechanisms of metal-based therapeutics
Apexbio Technology LLC Cyclamic acid 100-88-9 50mg
Cyclamic acid (CAS nan) is a model compound used to explore receptor-ligand interactions in gustatory receptor pathways It is designed to investigate taste receptor protein engagement and metabolic response mechanisms thereby informing studies of taste receptor signaling and metabolic processing Cyclamic acid exerts its biological activity primarily through interaction with taste receptor proteins characterized by its cyclic sulfamate moiety In studies focused on gustatory receptor pathways and metabolic response mechanisms cyclamic acid serves as a representative model compound Based on these pharmacological properties cyclamic acid holds research potential in the investigation of taste receptor pharmacology and metabolic regulation
Apexbio Technology LLC Quinapril HCl 82586-55-8 10mM (in 1mL DMSO)
Quinapril hydrochloride (CAS 82586-55-8) is an esterified precursor that undergoes hepatic conversion to quinaprilat an active inhibitor of angiotensin-converting enzyme (ACE) By impeding the conversion of angiotensin I to angiotensin II quinapril modulates the renin-angiotensin-aldosterone system resulting in decreased vasoconstriction and reduced aldosterone secretion This molecule is frequently utilized in cardiovascular research to investigate mechanisms underlying hypertension heart failure and the biological effects of ACE inhibition on vascular and renal systems
Apexbio Technology LLC 3-aminobenzamide 3544-24-9 10mM (in 1mL DMSO)
3-Aminobenzamide (CAS 3544-24-9) is a potent inhibitor of poly(ADP-ribose) polymerase (PARP) exhibiting an IC50 of approximately 50 nM in CHO cell assays At concentrations above 1 M it suppresses over 95% of PARP activity without notable cytotoxicity In cellular models 3-aminobenzamide mitigates oxidative stress-induced endothelial dysfunction by enhancing acetylcholine-induced nitric oxide-mediated vasodilation following hydrogen peroxide exposure In vivo it has been shown to attenuate diabetic nephropathy in Leprdb/db mice by reducing albuminuria glomerular mesangial expansion and podocyte loss 3-Aminobenzamide serves as a valuable tool for PARP-related research in oxidative injury and metabolic disease models
Medchemexpress LLC Cardiac Troponin I Antibody (YA3484) | 100 UL
Cardiac Troponin I Antibody (YA3484) is a rabbit-derived, non-conjugated IgG monoclonal antibody, specifically targeting Cardiac Troponin I. This affinity-purified liquid antibody is reactive to Human Cardiac Troponin I. Cardiac Troponin I functions as the inhibitory subunit of troponin, a thin filament regulatory complex that imparts calcium-sensitivity to striated muscle actomyosin ATPase activity.
- Rabbit-derived IgG monoclonal antibody
- Non-conjugated
- Targets Cardiac Troponin I
- Reactive to human Cardiac Troponin I
- Affinity purified
- Supports WB, IHC-P, ICC/IF, IP applications
- Liquid appearance
- Store at -20°C for 1 year
- Avoid repeated freeze/thaw cycles