Organoheterocyclic compounds
3-Thiophenemethanol 96.0+%, TCI America™
CAS: 71637-34-8 Molecular Formula: C5H6OS Molecular Weight (g/mol): 114.16 MDL Number: MFCD00014534 InChI Key: BOWIFWCBNWWZOG-UHFFFAOYSA-N Synonym: 3-thiophenemethanol,3-thienylmethanol,thiophene-3-methanol,3-thiophene methanol,3-hydroxymethylthiophene,thien-3-ylmethanol,thiophen-3-yl methanol,3-thienylmethan-1-ol,3-hydroxymethyl thiophene,3-thiophenylmethanol PubChem CID: 123570 IUPAC Name: (thiophen-3-yl)methanol SMILES: OCC1=CSC=C1
2-Hydroxy-3-methyl-5-nitropyridine 98.0+%, TCI America™
CAS: 21901-34-8 Molecular Formula: C6H6N2O3 Molecular Weight (g/mol): 154.125 InChI Key: FPTYZBDNBMVYCL-UHFFFAOYSA-N Synonym: 2-hydroxy-3-methyl-5-nitropyridine,3-methyl-5-nitropyridin-2-ol,2-hydroxy-5-nitro-3-picoline,3-methyl-5-nitro-2-pyridone,2-hydroxy-5-nitro-3-methylpyridine,2 1h-pyridinone, 3-methyl-5-nitro,3-methyl-5-nitro-2 1h-pyridinone,3-methyl-5-nitro-2-pyridinol,3-methyl-5-nitro-pyridin-2-ol,6-hydroxy-5-methyl-3-nitropyridine PubChem CID: 89097 IUPAC Name: 3-methyl-5-nitro-1H-pyridin-2-one SMILES: CC1=CC(=CNC1=O)[N+](=O)[O-]
N″-Biotinyl-6-aminohexanoylhydrazide 97.0+%, TCI America™
CAS: 109276-34-8 Molecular Formula: C16H29N5O3S Molecular Weight (g/mol): 371.5 MDL Number: MFCD00077659 InChI Key: IJJWOSAXNHWBPR-HUBLWGQQSA-N Synonym: Biotin-LC-Hydrazide, N-(6-Hydrazinyl-6-oxohexyl)biotinamide PubChem CID: 83900 IUPAC Name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-(6-hydrazinyl-6-oxohexyl)pentanamide SMILES: C1C2C(C(S1)CCCCC(=O)NCCCCCC(=O)NN)NC(=O)N2
tert-Butyl 3-Carbamoylpyrrolidine-1-carboxylate 98.0+%, TCI America™
CAS: 122684-34-8 Molecular Formula: C10H18N2O3 Molecular Weight (g/mol): 214.265 MDL Number: MFCD04116210 InChI Key: NHDGOVOBEZPXMY-UHFFFAOYSA-N Synonym: 3-aminocarbonyl-1-boc-pyrrolidine,1-boc-3-carbamoylpyrrolidine,1-boc-pyrrolidine-3-carboxamide,3-carbamoyl-pyrrolidine-1-carboxylic acid tert-butyl ester,1-boc-pyrrolidine-3-carboxyamide,tert-butyl 3-aminocarbonyl pyrrolidine-1-carboxylate,acmc-20a2cc,ksc496a4t,1-boc-3-pyrrolidinecarboxamide,1-n-boc-pyrrolidine-3-carboxyamide PubChem CID: 4571096 IUPAC Name: tert-butyl 3-carbamoylpyrrolidine-1-carboxylate SMILES: CC(C)(C)OC(=O)N1CCC(C1)C(=O)N
Apexbio Technology LLC AMG-208 1002304-34-8 100mg
AMG-208 (CAS 1002304-34-8) is a highly selective small molecule inhibitor of the receptor tyrosine kinase c-Met which is the endogenous receptor for hepatocyte growth factor (HGF) and is involved in cellular processes such as proliferation migration and invasion AMG-208 exhibits potent c-Met inhibition with an IC50 of 9 3 nM in enzymatic assays and effectively blocks HGF-induced c-Met phosphorylation in PC3 cells with an IC50 of 46 nM In human liver microsome studies AMG-208 showed time-dependent inhibition of CYP3A4 activity Pharmacokinetic evaluation in rats demonstrated high bioavailability and a moderate elimination half-life Dysregulation of c-Met has been implicated in multiple human cancers supporting AMG-208 s utility as a research tool in oncology
Medchemexpress LLC Bexobrutideg | 2649400-34-8 | C42H54N12O5 | 100 MG
Bexobrutideg | 2649400-34-8 | C42H54N12O5 | 100 MG
Medchemexpress LLC Bexobrutideg | 2649400-34-8 | C42H54N12O5 | 5 MG
Bexobrutideg | 2649400-34-8 | C42H54N12O5 | 5 MG
Apexbio Technology LLC AMG-208 1002304-34-8 25mg
AMG-208 (CAS 1002304-34-8) is a highly selective small molecule inhibitor of the receptor tyrosine kinase c-Met which is the endogenous receptor for hepatocyte growth factor (HGF) and is involved in cellular processes such as proliferation migration and invasion AMG-208 exhibits potent c-Met inhibition with an IC50 of 9 3 nM in enzymatic assays and effectively blocks HGF-induced c-Met phosphorylation in PC3 cells with an IC50 of 46 nM In human liver microsome studies AMG-208 showed time-dependent inhibition of CYP3A4 activity Pharmacokinetic evaluation in rats demonstrated high bioavailability and a moderate elimination half-life Dysregulation of c-Met has been implicated in multiple human cancers supporting AMG-208 s utility as a research tool in oncology
Apexbio Technology LLC AMG-208 1002304-34-8 5mg
AMG-208 (CAS 1002304-34-8) is a highly selective small molecule inhibitor of the receptor tyrosine kinase c-Met which is the endogenous receptor for hepatocyte growth factor (HGF) and is involved in cellular processes such as proliferation migration and invasion AMG-208 exhibits potent c-Met inhibition with an IC50 of 9 3 nM in enzymatic assays and effectively blocks HGF-induced c-Met phosphorylation in PC3 cells with an IC50 of 46 nM In human liver microsome studies AMG-208 showed time-dependent inhibition of CYP3A4 activity Pharmacokinetic evaluation in rats demonstrated high bioavailability and a moderate elimination half-life Dysregulation of c-Met has been implicated in multiple human cancers supporting AMG-208 s utility as a research tool in oncology
Medchemexpress LLC Thyroglobulin 25mg | 9010-34-8 | 25MG
Thyroglobulin is a 660 kDa dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3) as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle[1
Medchemexpress LLC Thyroglobulin 50mg | 9010-34-8 | 50MG
Thyroglobulin is a 660 kDa dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3) as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle[1
Apexbio Technology LLC Acalisib (GS-9820) 870281-34-8 10mg
Acalisib (GS-9820 CAS 870281-34-8) is a potent and selective inhibitor of phosphoinositide 3-kinase delta (PI3K ) exhibiting an IC50 of 12 7 nM for this isoform PI3K predominantly expressed in hematopoietic cells is involved in modulating inflammatory responses immune cell function migration and vesicular trafficking Acalisib demonstrates high selectivity with much higher IC50 values for PI3K (5441 nM) PI3K (3377 nM) and PI3K (1389 nM) In cellular assays acalisib inhibits PI3K -mediated processes such as Fc RI-stimulated CD63 expression in basophils (EC50 14 nM) and affects osteoclast cytoskeletal organization and survival This compound is valuable for investigating PI3K signaling in immune and bone biology research
Medchemexpress LLC Acalisib | 870281-34-8 | 99.98% | 401.40 | 100MG
Acalisib is a potent and selective PI3Kδ inhibitor with an IC50 of 12.7 nM. It is for research use only and not sold to patients.
- More selective for PI3Kδ (IC50=12.7 nM) compared to other PI3K class I enzymes.
- Reduces PDGF-induced pAkt by 50% at 11,585 nM and LPA-induced pAkt by 50% at 2,069 nM in fibroblasts.
- Sufficient to reduce the growth of multiple myeloma xenografts in mice.
Medchemexpress LLC Acalisib | 870281-34-8 | 99.98% | 401.40 | 5 MG
Acalisib is a potent and selective PI3Kδ inhibitor with an IC50 of 12.7 nM. It demonstrates high selectivity against other PI3K class I enzymes and related kinases, making it suitable for targeted research. Studies have shown its effectiveness in reducing the growth of multiple myeloma xenografts in mice. This product is for research use only.
- Potent and selective PI3Kδ inhibitor
- IC50 of 12.7 nM against PI3Kδ
- High selectivity over other PI3K class I enzymes
- Reduces growth of multiple myeloma xenografts in mice
- For research use only
Medchemexpress LLC Ceftibuten dihydrate | 118081-34-8 | 99.2% | 5 MG
Ceftibuten dihydrate is an orally active cephalosporin antibiotic that demonstrates potent in vitro activity against a wide range of gram-negative and certain gram-positive pathogens. This biologically stable β-lactam antibiotic is transported by the small peptide transport system and is intended for research use only.
- Orally active cephalosporin antibiotic
- Potent activity against gram-negative and certain gram-positive pathogens
- Highly active against *Haemophilus influenza*, *Escherichia coli*, *Klebsiella* sp., and *Proteus* sp.
- Stable against most β-lactamase-producing organisms
- Biologically stable β-lactam antibiotic
- Transported by the small peptide transport system
- For research use only