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Tin Protoporphyrin IX dichloride is a potent inhibitor of heme oxygenase-1 (HO-1) reduces ozone-induced pulmonary inflammation and BAL cell necrosis highlighting its protective role It also sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in a mouse model suggesting its potential for PDAC treatment
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Also available in 1 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses. Purity 98%
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Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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Tin protoporphyrin IX dichloride is a metalloporphyrin research reagent that acts as a potent inhibitor of heme oxygenase enzymes. It is provided as a milligram-scale crystalline solid intended for biochemical and cell-based studies to probe heme metabolism, oxidative stress, and related pathways.
Potent inhibitor of heme oxygenase enzymes.
Suitable for in vitro and in vivo research applications.
Available in milligram-scale sizes, including 100 MG.
High reported purity for research use (approximately 96.2%).
Supplied as a stable solid for routine laboratory handling.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Tin protoporphyrin IX dichloride is a tin-containing porphyrin analog used as a research reagent to inhibit heme oxygenase-1 (HO-1) and study heme metabolism and related cellular pathways.
Potent heme oxygenase-1 (HO-1) inhibitor for mechanistic studies.
Suitable for biochemical and cellular assays.
High purity (96.2%) for reproducible results.
Chemical formula C34H32Cl2N4O4Sn; molecular weight 750.26 g/mol.
Available in multiple vial sizes, including 25 mg.
Store sealed, away from moisture; in solvent, -80°C for up to 6 months.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More