Phenylpropanoids and polyketides
Apexbio Technology LLC Tyrphostin A1 2826-26-8 25mg
Tyrphostin A1 (CAS 2826-26-8) is a small molecule inhibitor targeting tyrosine kinase activity specifically involved in disrupting intracellular signaling pathways in immune cells It has been shown to interfere with CD40 ligand-induced signaling resulting in suppressed interleukin-12 (IL-12) secretion by macrophages and reduced differentiation of antigen-induced T helper 1 (Th1) cells Tyrphostin A1 is widely utilized in studies investigating cell-to-cell signaling immune response modulation and the mechanisms underlying inflammatory processes particularly in the context of autoimmune disease models
Medchemexpress LLC (Z)-Entacapone | 145195-63-7 | MFCD00866580 | >98.0% | C14H15N3O5 | 10MG
(Z)-Entacapone is the Z-isomer of entacapone, a catechol-O-methyltransferase (COMT) inhibitor supplied for research and analytical use. It is commonly used as a reference or impurity standard and for studies of COMT activity, metabolism, and degradation pathways. The compound has molecular formula C14H15N3O5 and CAS 145195-63-7.
- High chemical purity (>98.0%).
- Suitable as a reference or impurity standard for analytical assays.
- Applicable for studies of COMT activity, metabolism, and degradation.
- Provided as a solid in small-quantity packs for research use.
- Well characterized molecular identity (C14H15N3O5; CAS 145195-63-7).
Medchemexpress LLC Entacapone | 130929-57-6 | 99.2% | C14H15N3O5 | 25 MG
Entacapone | 130929-57-6 | 99.2% | C14H15N3O5 | 25 MG
Medchemexpress LLC (2E,4E)-Hepta-2,4-dienal | 4313-03-5 | 90.6% | 110.16 | 5 G
(2E,4E)-Hepta-2,4-dienal is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is for research use only and not sold to patients.
- Can be used as a biological material or organic compound for life science related research
- For research use only
- Not sold to patients
TARGETMOL CHEMICALS INC TYRPHOSTIN AG1296 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 uM no activity to EGFR. purity: 99%
Selleck Chemical LLC Tyrphostin AG 1296
Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0 3-0 5 M no activity to EGFR Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12 3 M and 1 8 M in Swiss 3T3 cells Tyrphostin AG1296 induces dramatic apoptosis in A375R cells
![Medchemexpress LLC 2-Propenethioamide, 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-, (2E)- | 148741-30-4 | 99.3% | 316.46 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000402443-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Propenethioamide, 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-, (2E)- | 148741-30-4 | 99.3% | 316.46 | 25 MG
Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation with an IC50 of 10 μM, but not TrKB and TrKC. It is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, showing at least 500-fold higher selectivity for ErbB2 over EGFR. This compound exhibits anticancer activity.
- Significantly decreases cell proliferation in various cell lines
- Induces a dose-dependent increase in apoptosis
- Reduces tumor sizes in animal models