Phenylpropanoids and polyketides
Medchemexpress LLC Entacapone (Standard) | 130929-57-6 | 99.2% | C14H15N3O5 | 100 MG
Entacapone (Standard) | 130929-57-6 | 99.2% | C14H15N3O5 | 100 MG
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | 98.0% | 170.17 g/mol | C10H6N2O | 5 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor supplied for research use. It inhibits EGFR kinase (IC50 = 560 μM), acts as a GTPase inhibitor, and inhibits calcineurin (IC50 = 21 μM). The compound is provided as a high-purity solid and is available in small-mass vials or as a DMSO solution for in vitro biochemical and cell-based assays.
- High purity (>98%), suitable for in vitro studies.
- Known activity against EGFR, GTPase, and calcineurin targets.
- Molecular weight 170.17 g/mol and formula C10H6N2O.
- Available in multiple small pack sizes and as a 10 mM DMSO solution.
- Light yellow to yellow solid for handling and storage.
TARGETMOL CHEMICALS INC ENTACAPONE 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT). purity: 99%
Medchemexpress LLC Luteolin-3′,7-diglucoside | 52187-80-1 | 1 MG
Luteolin-3′,7-diglucoside is a glycoside isolated from *R. luteolin* that significantly inhibits cataracts induced in ovine lenses and inhibits the activity of *Ureaplasma urealyticum* ATCC and clinical strains. It works by counteracting IL1-induced tissue factor expression in monocytes, thus inhibiting procoagulant activity. This compound also demonstrates a significant ability to inhibit cataracts in ovine lenses when incubated in hypotonic hepes buffered solution.
- Molecular weight: 610.52
- Formula: C₂₇H₃₀O₁₆
- Appearance: Solid
- Color: Light yellow to yellow
- Structure classification: Flavonoids, isoflavones
- Initial source: Plants, Solanaceae, *Alkekengi officinarum Moench*
- Inhibits procoagulant activity in monocytes
- Significantly inhibits cataracts induced in ovine lenses
- Inhibits *Ureaplasma urealyticum* activity
Medchemexpress LLC Kaempferol 3,7,4'-trimethyl ether | 15486-34-7 | 98.0% | 328.32 g/mol | C18H16O6 | 10 MG
Kaempferol 3,7,4'-trimethyl ether is a naturally occurring flavonol aglycone isolated from the leaves of Siparuna gigantotepala. It is supplied as a research-grade reference compound and is reported to exhibit antioxidant activity. The compound has formula C18H16O6, molecular weight 328.32 g/mol, CAS 15486-34-7, and is provided with 98.0% purity.
- Naturally derived flavonol aglycone
- Exhibits antioxidant activity
- High purity: 98.0%
- Molecular formula C18H16O6; molecular weight 328.32 g/mol
- Supplied as a solid reference for research applications
- Available in small pack sizes suitable for compound screening and analytical work
Medchemexpress LLC (-)-Epigallocatechin | 970-74-1 | MFCD00075939 | >95.0% | 306.27 | C15H14O7 | 10 MG
(-)-Epigallocatechin is an analytical reference standard of a flavonoid commonly found in green tea, provided for research and analytical applications such as studies of matrix metalloproteinases and autophagy. It has molecular formula C15H14O7 and molecular weight 306.27 g/mol. Store and handle according to the Certificate of Analysis; for research use only.
- Analytical reference standard for method development and quality control.
- Intended for research and analytical applications, including MMP and autophagy assays.
- Molecular formula C15H14O7 and molecular weight 306.27 g/mol.
- Purity >95.0% (HPLC).
- Supplied in milligram-scale quantities for analytical use; follow CoA for storage and handling.
Abcam (-)-Epigallocatechin, Antio x idant activity, 10MG
MW 306.27 Da, Purity >98%. Antioxidant and anti-tumor promoter activity. Induces apoptosis and inhibits angiogenesis.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Entacapone | 130929-57-6 | 99.97% | C14H15N3O5 | 50 MG
Entacapone is a potent, reversible, peripherally acting, and orally active catechol-O-methyltransferase (COMT) inhibitor. It is selective for COMT over other catecholamine metabolizing enzymes and can be used for Parkinson's disease research. Entacapone also inhibits FTO demethylation, making it relevant for metabolic disorders research.
- Inhibits COMT with IC50 values in the nanomolar range
- Demonstrates agonist activity at GPR35 in HT-29 and U2OS cells
- Enhances m6A on mRNA in Hep-G2 cells
- Decreases body weight and fat mass in obese mouse models
- Reduces total cholesterol, low-density lipoprotein cholesterol, and triglycerides
Medchemexpress LLC Coumarin (standard) | 91-64-5 | 146.14 | 50 MG
Coumarin (Standard) is the analytical standard of Coumarin, intended for research and analytical applications. It is a potent and orally active anti-inflammatory agent, and also shows antinociceptive, antibacterial, antifungal, and anticancer activity. This product is for research use only and not sold to patients.
- The compound is a grade of analytical standard, serving as a reference standard for assays.
- Commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Appearance: solid
- Color: white to off-white
- Structure classification: phenylpropanoids, coumarins
- Initial source: plants (Compositae Ambrosia psilostachya DC., Umbelliferae), microorganisms.
Medchemexpress LLC (+)-Catechin | 154-23-4 | MFCD00075649 | 99.1% | 290.27 g/mol | C15H14O6 | 10 MG
Catechin (Standard) is an analytical reference material of (+)-catechin supplied as a quantified, high-purity compound for research, method development, and quality-control applications.
- Analytical reference standard for assay calibration and method validation.
- High purity 99.1% documented by a certificate of analysis.
- Provided in a 10 mg primary package suitable for analytical use.
- Characterized by molecular formula C15H14O6 and molecular weight 290.27 g/mol.
- Certificate of analysis and safety data sheet available for traceability and safety compliance.
Medchemexpress LLC (-)-Epigallocatechin-3-(3''-O-methyl) gallate | 83104-87-4 | MFCD06799452 | 99.8% | 472.40 g/mol | C23H20O11 | 10 MG
(-)-Epigallocatechin-3-(3''-O-methyl) gallate is a methylated epigallocatechin derivative commonly used in biochemical and pharmacological research to study antioxidant and anticancer activities. It is provided in small quantities for screening, analytical, and cellular assays.
- High purity (HPLC 99.8%)
- Molecular weight 472.40 g/mol
- Chemical formula C23H20O11
- CAS number 83104-87-4
- Supplied as a 10 mg research reagent suitable for assay development and compound screening
Abcam Apigenin, Anticancer agent, 10MG
MW 270.24 Da, Purity >98%. Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.
The product is subject to the following: Abcam Restricted Use Statement