Phenylpropanoids and polyketides
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | MFCD00020189 | 98.0% | 170.17 g/mol | C10H6N2O | 10 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor used as a research reagent to investigate EGFR signaling and related pathways. The compound is supplied as a light yellow to yellow solid with high reported purity and is offered in multiple solid sizes and DMSO solution formats.
- Inhibits EGFR kinase; reported IC50 ≈ 560 μM
- Also exhibits GTPase inhibitory activity
- High purity for reproducible experimental results
- Available as solid and as 10 mM DMSO solution in multiple sizes
- Storage recommended: solid at 4°C under nitrogen; solutions at -80°C or -20°C
TARGETMOL CHEMICALS INC SAR405 R enantiomer 5MG
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes.SAR405 (R enantiomer) is the less active form of SAR405, an inhibitor of PIK3C3/Vps34. Purity 98.04%
Sigma Aldrich Fine Chemicals Biosciences Rivaroxaban R enantiomer U20MG
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 10MG
SAR405 R enantiomer is the less active stereoisomer of the PIK3C3/Vps34 inhibitor SAR405, provided as a solid for in vitro research use only. It is suited for comparative pharmacology and control studies and includes handling and storage guidance for reliable experimental use.
- Less active enantiomer used as a comparative control in assays.
- High purity (≈99.9%).
- Solid, white to off-white appearance.
- Molecular formula C19H21ClF3N5O2; molecular weight 443.85.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store powder at -20°C for long-term stability; store solutions at -80°C.
- Intended for laboratory research use only.
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | 98.0% | 170.17 g/mol | C10H6N2O | 5 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor supplied for research use. It inhibits EGFR kinase (IC50 = 560 μM), acts as a GTPase inhibitor, and inhibits calcineurin (IC50 = 21 μM). The compound is provided as a high-purity solid and is available in small-mass vials or as a DMSO solution for in vitro biochemical and cell-based assays.
- High purity (>98%), suitable for in vitro studies.
- Known activity against EGFR, GTPase, and calcineurin targets.
- Molecular weight 170.17 g/mol and formula C10H6N2O.
- Available in multiple small pack sizes and as a 10 mM DMSO solution.
- Light yellow to yellow solid for handling and storage.
Apexbio Technology LLC Tyrphostin AG 1296 146535-11-7 100mg
Tyrphostin AG 1296 (CAS 146535-11-7) is a selective inhibitor of platelet-derived growth factor receptor (PDGFR) kinase via ATP-competitive binding Its inhibitory activity (IC50 0 3 0 5 M) results from inducing conformational changes in the ATP-binding domain of PDGFR blocking receptor autophosphorylation induced by ligand binding In vitro studies demonstrate inhibition of PDGF-stimulated mitogenesis (IC50 1 5 M) and cell proliferation (IC50 3 2 M) using Swiss 3T3 cells without significant effects on EGF receptor signaling at concentrations up to 100 M Tyrphostin AG 1296 serves as a research tool for investigating PDGFR-mediated signaling pathways
Selleck Chemical LLC AG 494
AG-494 a member of the tyrphostin family of tyrosine kinase inhibitors is a potent inhibitor of EGF receptor autophosphorylation (IC50 1 2 M) and EGF-dependent cell growth (IC50 6 M)
Apexbio Technology LLC Entacapone 130929-57-6 10mM (in 1mL DMSO)
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Selleck Chemical LLC Tyrphostin AG-528
Tyrphostin AG-528 (Tyrphostin B66) is a potent inhibitor of epidermal growth factor receptors (EGFR) and ErbB2/HER2 with IC50 of 4 9 M and 2 1 M respectively Tyrphostin AG-528 exhibits anticancer activity
Medchemexpress LLC Ozagrel hydrochloride | 78712-43-3 | 99.9% | 100 MG
Ozagrel hydrochloride | 78712-43-3 | 99.9% | 100 MG
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 1 ML
4-Methoxycinnamic acid | 830-09-1 | 178.19 | 1 ML
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
Medchemexpress LLC 3-Methylcinnamic acid | 3029-79-6 | 99.77% | C10H10O2 | 5 G
3-Methylcinnamic acid is a drug intermediate utilized in the synthesis of various active compounds. This product is strictly for research use only and is not intended for patient administration. Careful handling and storage are recommended to maintain product integrity and safety.
- Store powder at -20°C for up to 3 years or at 4°C for 2 years.
- When in solvent, store at -80°C for 6 months or at -20°C for 1 month.
- Avoid breathing dust, fume, gas, mist, vapors, or spray.
- Wash hands thoroughly after handling.
- Use only outdoors or in a well-ventilated area.
- Wear appropriate protective equipment including gloves, clothing, and eye/face protection.
- May cause irritation to skin, eyes, and respiratory tract.
eMolecules 3,4-Dichlorocinnamic Acid | 1202-39-7 | MFCD00004385 | 25g
Ambeed | 3,4-Dichlorocinnamic Acid | 25g | 600843378 | A574837 | | 1202-39-7 | MFCD00004385 | 217.050 | C9H6Cl2O2
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Accela Chembio Inc 4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 5g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 5g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive