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Commonly in liquid form and available in various chemical compositions, solvents are substances that dissolve solutes to form solutions. The amount and type of solute that a solvent can dissolve is dependent upon temperature and polarity.
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Glyburide-d3 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor used for diabetes and obesity research. It inhibits P-glycoprotein, directly binds and blocks the SUR1 subunits of KATP, and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). It interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability and can induce autophagy.
Used as a tracer.
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Inhibits P-glycoprotein.
Blocks SUR1 subunits of KATP.
Inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR).
Interferes with mitochondrial bioenergetics.
Induces autophagy.
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Tipranavir-d7 is a deuterated form of Tipranavir. Tipranavir is known to inhibit the enzymatic activity and dimerization of HIV-1 protease. It demonstrates potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates, with IC50s ranging from 66-410 nM. Additionally, Tipranavir has been shown to inhibit SARS-CoV-2 3CLpro activity.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Exerts potent activity against a wide spectrum of wild-type and multi-PI-resistant HIV-1 variants.
Inhibits the enzymatic activity of HIV-1 protease.
Blocks the dimerization of protease subunits.
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(±)-Naproxen-d3 is the deuterium labeled (±)-Naproxen, which is a non-steroidal anti-inflammatory drug (NSAID). It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Purity of 99.77%
Can be used as a tracer
Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Molecular weight of 233.28
Solid appearance
Off-white to light yellow color
Soluble in DMSO at 100 mg/mL
Powder stable for 3 years at -20°C and 2 years at 4°C
Stable in solvent for 6 months at -80°C and 1 month at -20°C
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Fmoc-Ser-OH-d3 is the deuterium labeled Fmoc-Ser-OH. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Used as a tracer
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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