Diterpenoids
Medchemexpress LLC Nab-Paclitaxel 25mg | 25mg
Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015) Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability Nab-Paclitaxel displays less toxicity and greater antitumor activity Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma seven neuroblastoma cell lines and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors (The product specifications below only indicate the effective content of Paditaxel the actual albumin quality depends on the batch the ratio of each ingredient in this product is Paditaxel albumin -1 7 1 11)[1][2]
Medchemexpress LLC (5E,9E,13E)-teprenone | 3796-63-2 | 99.9% | 330.56 g/mol | C23H38O | 10 MG
(5E,9E,13E)-teprenone is a geranylgeranyl-derived small molecule used in research to induce heat shock proteins (HSPs) and to study gastric mucosal protection. Supplied as a high-purity reagent suitable for biochemical and cellular assays.
- High purity (99.9%) suitable for research applications.
- CAS number 3796-63-2 for unambiguous identification.
- Chemical formula C23H38O; molecular weight 330.56 g/mol.
- Supplied as a 10 mg pack for small-scale experiments.
- Recommended storage: 4°C; in solvent: -80°C (6 months) or -20°C (1 month) under nitrogen.
Medchemexpress LLC Docetaxel (standard) | 114977-28-5 | 99.9% | C43H53NO14 | 100 MG
Docetaxel (standard) is an analytical standard of Docetaxel, developed for research and analytical applications. It functions as a microtubule depolymerization inhibitor and attenuates the effects of bcl-2 and bcl-xL gene expression. This compound arrests the cell cycle at G2/M and induces cell apoptosis, demonstrating anti-cancer activity.
- Acts as a microtubule depolymerization inhibitor
- Attenuates bcl-2 and bcl-xL gene expression
- Arrests cell cycle at G2/M
- Induces cell apoptosis
- Utilized in qualitative, quantitative, and methodological research experiments (e.g., HPLC, GC, MS)
- Appears as a white to off-white solid
Cayman Chemical -AphIdIcolIn 25mg
A natural tetracyclic diterpene with antiviral activity against herpes simplex; a cell-permeable, reversible inhibitor of DNA replication in eukaryotic cells, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels.
Cayman Chemical -AphIdIcolIn 1mg
A natural tetracyclic diterpene with antiviral activity against herpes simplex; a cell-permeable, reversible inhibitor of DNA replication in eukaryotic cells, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels.
Sigma Aldrich Fine Chemicals Biosciences Aphidicolin from Nigrospora sphaerica | 38966-21-1 | MFCD00083214 | 1mg
Aphidicolin from Nigrospora sphaerica | 38966-21-1 | MFCD00083214 | 1mg
Apexbio Technology LLC Resiniferatoxin 1mg
Resiniferatoxin (CAS 57444-62-9) is a potent selective agonist of the transient receptor potential vanilloid 1 (TRPV1) channel derived from plant sources By activating TRPV1 it induces sustained calcium influx in TRPV1-expressing sensory neurons leading to their desensitization or ablation In animal studies resiniferatoxin has been shown to induce long-lasting elimination of TRPV1-positive primary sensory afferents and blunt associated neural reflexes including those mediating cardiac sympathetic input Resiniferatoxin is widely used in research to investigate pain pathways sensory neuron function and neurogenic inflammation
Medchemexpress LLC Resiniferatoxin | 57444-62-9 | 1 MG
Resiniferatoxin is a selective agonist of the transient receptor potential vanilloid 1 (TRPV1) receptor. It can be isolated from the Euphorbia resinifera plant. It eliminates TRPV1+ primary sensory afferents and blunts cardiac sympathetic afferent reflex for a relatively long period.
- Purity of 99.77%
- Molecular weight: 628.71
- Chemical formula: C37H40O9
- Appearance: Solid
- Causes prolonged channel opening and calcium influx
- Leads to cytotoxicity in TRPV1-positive pain fibers or cell bodies
Medchemexpress LLC Paclitaxel-d5 | 1129540-33-5 | 99.9% | C47H46D5NO14 | 500 UG
Paclitaxel-d5 is a deuterium-labeled Paclitaxel, a naturally occurring antineoplastic agent that stabilizes tubulin polymerization. Deuteration has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules as tracers for quantitation during the drug development process.
Selleck Chemical LLC Nab-Paclitaxel-E1068-100MG
Nab-Paclitaxel is a novel solvent-free paclitaxel in which the binding ratio of paclitaxel to human albumin is approximately 1 9 It is an anti-microtubule drug that promotes microtubule aggregation in tubulin dimers and inhibits microtubule depolymerization to stabilize the microtubule system Solutions are unstable and should be fresh-prepared