Diterpenoids
Medchemexpress LLC Phytol | 150-86-7 | 1 ML
Phytol ((E)-Phytol) is an orally active diterpenoid alcohol extracted from chlorophyll. It exhibits antioxidant, anti-inflammatory, anti-schistosomiasis, and antibacterial activities. It is intended for research use only and not for sale to patients.
- Exhibits antioxidant activity
- Shows anti-inflammatory properties
- Possesses anti-schistosomiasis activity
- Demonstrates antibacterial activities
- Reduces motor activity and causes death in worms
- Inhibits osteoclast differentiation and oxidative stress
- Reduces parasite numbers in mice infected with C. mansoni
- Improves anemia and oxidative brain damage in Plasmodium berghei infected mice
Medchemexpress LLC Phytol (Standard) | 150-86-7 | 25 MG
Phytol (Standard) is an orally active diterpenoid alcohol that serves as an analytical standard. It can be extracted from chlorophyll and exhibits antioxidant, anti-inflammatory, anti-schistosomiasis, and antibacterial activities. This product is intended for research and analytical applications.
- Analytical standard for research and analytical applications
- Extracted from chlorophyll
- Exhibits antioxidant activity
- Exhibits anti-inflammatory activity
- Exhibits anti-schistosomiasis activity
- Exhibits antibacterial activity
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Cayman Chemical Mulberry leaf Phytol 100g
A degradation product of chlorophyll that is converted to phytanic acid, which can accumulate to toxic levels in a number of metabolic disorders; activates RXRs (Kis range from 2.3-67.2 µM) and promotes the activity of PPAR/RXR heterodimers
Apexbio Technology LLC Phytol 150-86-7 250g
Phytol is a naturally occurring diterpene alcohol derived from chlorophyll metabolism serving as an activator for retinoid X receptors (RXRs) RXRs are nuclear hormone receptors implicated in transcriptional regulation and cellular differentiation through ligand-dependent signaling pathways involving vitamins and hormones Phytol activates RXRs displaying Ki values ranging from 2 3 to 67 2 M In mammals phytol is metabolized to phytanic acid a reaction regulated by peroxisome proliferator-activated receptor (PPAR ) Additionally phytol interacts with GABA A receptors exhibiting sedative and anxiolytic properties and has been investigated as an antischistosomal candidate in animal models
Medchemexpress LLC (5E,9E,13E)-Teprenone | 3796-63-2 | 99.9% | 100 MG
(5E,9E,13E)-Teprenone is an isomer with antiulcer activity. It induces the transcriptional activation of HSP genes, which may enhance gastric mucosal defense under stress conditions.
- Antiulcer activity.
- Induces transcriptional activation of heat shock protein protein genes.
- May increase gastric mucosal defense at conditions of stress.
- Available in various quantities.
- Purity of 99.9%.
Sigma Aldrich Fine Chemicals Biosciences Geranylgeranylacetone | 6809-52-5 | MFCD00869547 | 10MG
Geranylgeranylacetone | Purity: >=98% (HPLC) | Mol Wt: 330.55 | 6809-52-5 | MFCD00869547 | 10MG
Medchemexpress LLC Dihydrotanshinone I | 87205-99-0 | 278.30 | 50 MG
Dihydrotanshinone I | 87205-99-0 | 278.30 | 50 MG
Medchemexpress LLC Isotanshinone IIA | 20958-15-0 | 5 MG
Isotanshinone IIA is an abietane-type diterpene metabolite that non-competitively inhibits Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 of 11.4 μM. Intended for research use only, this product is an orange to orange-red solid with 98.0% purity. It has a molecular weight of 294.34 and a chemical formula of C19H18O3.
- Non-competitive inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) activity
- IC50 of 11.4 μM
- 98.0% purity
- Appears as an orange to orange-red solid
- Molecular weight of 294.34
- Chemical formula of C19H18O3
- Classified under Quinones and Naphthalene Quinones
- Powder storage: -20°C for 3 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 3 mg/mL (10.19 mM)
Medchemexpress LLC Tanshinone IIA (Dan Shen ketone) | 568-72-9 | 99.78% | 294.34 | 5 MG
Tanshinone IIA is a primary component found in the root of Salvia miltiorrhiza Bunge. It may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2, and has anti-tumor effects including inhibiting tumor cell proliferation, disrupting the tumor cell cycle, promoting tumor cell apoptosis, and inhibiting tumor cell invasion and transfer.
- Has antiproliferative activity against various cell lines
- Protects rat myocardium-derived H9C2 cells against apoptosis
- Blocks the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells
Medchemexpress LLC Isotanshinone IIA | 20958-15-0 | 1 MG
Isotanshinone IIA is an abietane-type diterpene metabolite. It functions as a non-competitive inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 of 11.4 μM. This compound appears as an orange to orange-red solid and is intended for research use only.
- High purity: 98.0%
- IC50: 11.4 μM for PTP1B
- Molecular weight: 294.34
- Chemical formula: C19H18O3
- Appearance: Solid
- Color: Orange to orange-red
- Structure classification: Quinones, Naphthalene Quinones
- Initial source: Plants Leguminosae Samanea saman (Jacq.) Merr., Plants Labiatae
- Solubility in DMSO: 3 mg/mL (10.19 mM)
