Diterpenoids
Medchemexpress LLC Paclitaxel | 33069-62-4 | 99.97% | C47H51NO14 | 5 G
Paclitaxel is a naturally occurring antineoplastic agent that stabilizes tubulin polymerization. It can cause both mitotic arrest and apoptotic cell death, and it also induces autophagy.
- Naturally occurring antineoplastic agent.
- Stabilizes tubulin polymerization.
- Causes mitotic arrest.
- Induces apoptotic cell death.
- Induces autophagy.
Medchemexpress LLC Dihydrotanshinone I | 87205-99-0 | 278.30 | 100 MG
Dihydrotanshinone I is a natural compound extracted from *Salvia miltiorrhiza Bunge*, which has been widely used for treating cardiovascular diseases. It exhibits an entry-blocking effect for MERS-CoV.
- Natural compound extracted from *Salvia miltiorrhiza Bunge*.
- Used for treating cardiovascular diseases.
- Exhibits an entry-blocking effect for MERS-CoV.
Medchemexpress LLC Docetaxel (standard) | 114977-28-5 | 99.9% | C43H53NO14 | 5 MG
Docetaxel (Standard) is the analytical standard of Docetaxel, intended for research and analytical applications. Docetaxel (RP-56976) acts as a microtubule depolymerization inhibitor with an IC50 of 0.2 μM. It attenuates the effects of bcl-2 and bcl-xL gene expression, arrests the cell cycle at G2/M, and induces cell apoptosis, demonstrating anti-cancer activity.
- Serves as a grade of analytical standard, providing a reference standard for assays
- Commonly utilized in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS
Medchemexpress LLC Resiniferatoxin | 57444-62-9 | 5 MG
Resiniferatoxin is a selective agonist of the transient receptor potential vanilloid 1 (TRPV1) receptor. It can be isolated from the Euphorbia resinifera plant. This compound eliminates TRPV1+ primary sensory afferents and blunts cardiac sympathetic afferent reflex for a relatively long period.
- Selective agonist of TRPV1 receptor
- Isolated from Euphorbia resinifera plant
- Eliminates TRPV1+ primary sensory afferents
- Blunts cardiac sympathetic afferent reflex
- For research use only
Medchemexpress LLC Aphidicolin | 38966-21-1 | 5 MG
Aphidicolin is an inhibitor of DNA polymerase α and δ, which prevents mitotic cell division by interfering with DNA polymerase activity. It is an antibiotic produced by the mold Cephalosporium aphidicola. Aphidicolin inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. It also demonstrates anti-orthopoxvirus activity and enhances apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
- Inhibits DNA polymerase α and δ
- Prevents mitotic cell division
- Antibiotic from Cephalosporium aphidicola
- Inhibits DNA synthesis and herpes simplex virus growth
- Exhibits anti-orthopoxvirus activity
- Enhances apoptosis
- Selectively kills neuroblastoma cells
- Arrests cell cycle at G2 phase
- Inhibits cell proliferation via p53-GADD45β pathway
- Inhibits Varicella-zoster virus (VZV)
Medchemexpress LLC Docetaxel | 114977-28-5 | 99.9% | 807.88 | C43H53NO14 | 10 MG
Docetaxel (standard) is an analytical reference of the chemotherapeutic agent docetaxel supplied for research and analytical applications. It acts as a microtubule depolymerization inhibitor that arrests cells at G2/M and promotes apoptosis. The product is provided in small vial sizes for laboratory workflows and is accompanied by supporting documentation (SDS, COA).
- High purity suitable for analytical applications.
- Molecular weight 807.88.
- CAS number 114977-28-5 for unambiguous identification.
- Available in multiple small vial sizes for flexibility in experiments.
- Intended for research and analytical use only.
Medchemexpress LLC Resiniferatoxin | 57444-62-9 | 10 MM 1 ML
Resiniferatoxin is a selective agonist of the transient receptor potential vanilloid 1 (TRPV1) receptor. It can be isolated from the Euphorbia resinifera plant. It eliminates TRPV1+ primary sensory afferents and blunts cardiac sympathetic afferent reflex for a relatively long period. It is for research use only.
- Selective agonist for the transient receptor potential vanilloid 1 (TRPV1) receptor.
- Can be isolated from the Euphorbia resinifera plant.
- Eliminates TRPV1+ primary sensory afferents.
- Blunts cardiac sympathetic afferent reflex for a relatively long period.
- Causes prolonged channel opening and calcium influx, leading to cytotoxicity in TRPV1-positive pain fibers or cell bodies.
- For research use only.
Medchemexpress LLC Aphidicolin | 38966-21-1 | MFCD00083214 | 25 MG
Aphidicolin is an inhibitor of DNA polymerase α and δ, which functions by interfering with DNA polymerase activity to prevent mitotic cell division. This antibiotic, originating from the mold Cephalosporium aphidicola, is known for its ability to inhibit cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Furthermore, it demonstrates anti-orthopoxvirus activity and enhances apoptosis when induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
- Inhibits DNA polymerase α and δ
- Prevents mitotic cell division
- Functions as an antibiotic
- Inhibits cellular deoxyribonucleic acid synthesis
- Inhibits growth of herpes simplex virus
- Exhibits anti-orthopoxvirus activity
- Potentiates apoptosis induced by arabinosyl nucleosides
- Targets DNA/RNA synthesis, HSV, and apoptosis pathways
- Applied in infection and inflammation/immunology research
TARGETMOL CHEMICALS INC DIHYDROTANSHINONE I 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Dihydrotanshinone I (DHTS) is a natural compound extracted from Salvia miltiorrhiza Bunge used for treating of cardiovascular diseases. purity: 99%