Triterpenoids
Apexbio Technology LLC LUPEOL-10MG
Lupeol (CAS No 545-47-1) is a pentacyclic triterpenoid found in various fruits vegetables and medicinal plants It is primarily researched in the fields of oncology and pharmacology due to its potential anticancer anti-inflammatory and antioxidant properties Lupeol exerts its effects by modulating key signaling pathways such as PI3K/Akt and NF- B which are critical in cellular proliferation apoptosis and inflammation Its in vitro activity often ranges from nanomolar to low micromolar concentrations showcasing its potency in different experimental setups Lupeol s applications extend to various cancer cell lines animal models of inflammation and drug screening processes to explore its therapeutic potential against tumors and inflammatory diseases Experimental concentrations typically depend on the specific research design allowing researchers to tailor studies for acute or chronic exposure assessments
Cayman Chemical Betulinic Acid methyl ester, Purity: ≥95%, CAS: 2259-06-5, 1 mg
A triterpenoid and an esterified version of betulinic acid with diverse biological activities; inhibits HIV-1 reverse transcriptase (IC50 = 11 μM); active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively); induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM); cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively);
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 500mg, CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Apexbio Technology LLC Betulinic acid(Synonyms: Betulic acid, 3β-Hydroxy-lup-20(29)-en-28-oic acid, Lupatic acid, Betulonic acid), 500mg, CAS: 472-15-1.
Betulinic acid (CAS 472-15-1) is a pentacyclic triterpenoid obtained from natural sources exhibiting pharmacological properties relevant to oncology and infectious diseases research It induces apoptosis selectively in tumor cells by engaging mitochondrial apoptotic pathways independently of both p53 and CD95 signaling Additionally betulinic acid functions as an agonist for the bile acid receptor TGR5 demonstrating activity with an EC50 of approximately 1 04 M Due to its apoptotic effects and antiviral properties betulinic acid is extensively utilized in preclinical studies exploring cancer therapeutics and anti-HIV strategies
Medchemexpress LLC Oleanolic aldehyde | 17020-22-3 | 440.70 | 1 MG
Oleanolic aldehyde is an antimicrobial compound effective against oral bacteria like *Streptococcus mutans* and *Porphyromonas gingivalis*, which are implicated in dental caries and periodontal disease. This compound, classified as a triterpene, is naturally derived from plants such as *Vitis vinifera* cv. Zalema.
- Antimicrobial properties
- Inhibits *Streptococcus mutans* (MIC 488 μg/mL)
- Inhibits *Porphyromonas gingivalis* (MIC 250 μg/mL)
- Demonstrates growth inhibition in B16 2F2 epithelial cells
- Exhibits antiproliferative activity against +SA mammary epithelial cells
- Plant-derived triterpene
TARGETMOL CHEMICALS INC LUPEOL 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity. purity: 99%
Medchemexpress LLC Oleanolic acid 28-O-β-D-glucopyranoside | 14162-53-9 | 10 MG
Oleanolic acid 28-O-β-D-glucopyranoside is an orally active pentacyclic triterpenoid compound with anti-inflammatory effects. It can inhibit inflammatory responses, enhance intestinal epithelial barrier function, and modulate gut microbiota in ulcerative colitis models. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways. It can be used in the research of diseases such as colitis.
- Orally active pentacyclic triterpenoid compound
- Anti-inflammatory effects
- Inhibits inflammatory response
- Enhances intestinal epithelial barrier function
- Modulates gut microbiota
- Mechanism involves PI3K-AKT and MAPK signaling pathways
- Potential for research in diseases like colitis
- Purity: 99.42%
AdipoGen Limonin
Chemical. CAS 1180-71-8. Formula C26H30O8. MW 470.51. Synthetic. Limonin is the first described limonoid, which are naturally occurring tetranortriterpenoids that impart bitter flavor in citrus fruits. Compounds belonging to this group have reported anti-proliferative and proapoptotic activity on several cancer cell lines as well as pesticidal, anti-malarial, anti-microbial, anti-HIV, anti-inflammatory, antinociceptive and neuroprotective activity. Shown to inhibit arginase I and II and P-glycoprotein. May be used in assays as control, standard or competitor, or in studies on the physiology, metabolism and biosynthesis of limonin.
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 10mM (in 1mL DMSO), CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Apexbio Technology LLC Limonin 1180-71-8 200mg
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 99.1% | 456.70 g/mol | C30H48O3 | 200 MG
Betulinic acid is a naturally occurring pentacyclic triterpenoid used in research as an apoptosis inducer and bioactive small molecule. It is commonly used in pharmacology and cell biology to probe apoptotic pathways, evaluate anti-inflammatory and antiviral activity, and as a scaffold for synthetic derivatization.
- Natural pentacyclic triterpenoid compound.
- Functions as an apoptosis inducer in cellular assays.
- High purity suitable for research (≈99.1%).
- Available in multiple pack sizes for screening and synthesis workflows.
- Soluble in DMSO for preparation of stock solutions.
Sigma Aldrich Fine Chemicals Biosciences Squalene M.W.: 410.72 | CAS No.: 111-02-4 | MDL No.: MFCD00008912| 1g
Squalene 1G | M.W.: 410.72 | CAS No.: 111-02-4 | MDL No.: MFCD00008912| 1g
