Triterpenoids
Medchemexpress LLC Lupeol | 545-47-1 | 98.0% | 426.72 | 10 MG
Lupeol is an active pentacyclic triterpenoid with anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activity. It is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC). It has several potential medicinal properties, like anticancer and anti-inflammatory activity.
- Potent androgen receptor (AR) inhibitor
- Anti-oxidant activity
- Anti-mutagenic activity
- Anti-tumor activity
- Anti-inflammatory activity
- Used for cancer research, especially prostate cancer
TARGETMOL CHEMICALS INC Betulinic acid 500MG
Also available in 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. Purity ≥98%
Research Products International Corp Forskolin, 10 Milligrams
- CAS Number: 66575-29-9
- Molecular Formula: C22H34O7
- Molecular Weight: 410.5
Apexbio Technology LLC Glycyrrhizic acid 1405-86-3 20mg
Glycyrrhizic acid (CAS 1405-86-3) is a triterpenoid saponin antagonist targeting high mobility group box 1 (HMGB1) and inhibitor of monoamine oxidase (MAO) as well as cytochrome P450 enzymes (CYP3A4 CYP2C9 CYP2C19) and 11 -hydroxysteroid dehydrogenase type 2 (11 -HSD2) It is designed to antagonize HMGB1-mediated pro-inflammatory responses and oxidative stress inhibit the enzymatic activity of MAO and 11 -HSD2 and modulate cytochrome P450-mediated metabolism Glycyrrhizic acid exerts its biological activity primarily through competitive inhibition of these enzymes It demonstrates MAO inhibition with an IC50 of approximately 0 16 M and competitively inhibits CYP3A4 (IC50 8 2 M) CYP2C9 ( 42 9 M) and CYP2C19 ( 40 3 M) Based on these pharmacological properties glycyrrhizic acid holds research potential in anti-inflammatory pathways enzyme inhibition and glucose metabolic modulation
Selleck Chemical LLC Glycyrrhetinic acid
Glycyrrhetinic acid is a triterpenoid aglycone component of the natural product glycyrrhizinic acid and possesses remarkable anti-proliferative and apoptosis-inducing activity in various cancer cell lines
Apexbio Technology LLC 18α-Glycyrrhetinic acid 1449-05-4 10mg
18 -Glycyrrhetinic acid (CAS 1449-05-4) is a dietary-derived small molecule known to inhibit NF- B signaling while promoting proteasome activation Experimental studies have demonstrated that it enhances lifespan and exhibits anti-aggregation properties in multicellular organisms The compound also induces apoptosis in cellular models These activities highlight its potential utility in pharmacological research related to lifespan extension protein aggregation disorders and apoptosis-regulated diseases
Apexbio Technology LLC Limonin 1180-71-8 200mg
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Medchemexpress LLC Limonin (Standard) | 1180-71-8 | MFC26H30O8 | 99.1% | 470.51 | 50 MG
Limonin (Standard) is an analytical standard used for research and analytical applications. It exhibits antiviral and antitumor activities, including the inhibition of HIV-1 and induction of apoptosis in human colon adenocarcinoma cells. This standard is commonly employed in qualitative, quantitative, and methodological research experiments.
- Inhibits HIV-1 with an EC50 of 60.0 μM.
- Induces apoptosis in human colon adenocarcinoma cells with an IC50 of 54.74 μM.
- Used in HPLC, GC, and MS applications.
- Appears as a white to off-white solid.
- Classified as a terpenoid and triterpene.
- Initially sourced from plants of the Rutaceae family.
- Functions as an endogenous metabolite.
Cayman Chemical BetulInIc AcId methyl esTR 1mg
A triterpenoid and an esterified version of betulinic acid with diverse biological activities; inhibits HIV-1 reverse transcriptase (IC50 = 11 μM); active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively); induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM); cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively);
AdipoGen Betulinic acid (>97%) (1 g)
Betulinic acid (>97%) (1 g), Adipogen Life Sciences. Chemical. CAS: 472-15-1. Formula: C30H48O3. MW: 456.7. Isolated from Platanus acerifolia bark. Anti-HIV compound. Anticancer compound. Apoptosis inducer. Modulator of NF-kappaB. Potent DNA topoisomerase II inhibitor. Potent proteasome activator. Antimalarial compound.