Triterpenoids
Medchemexpress LLC Oleanolic aldehyde | 17020-22-3 | 440.70 | 1 MG
Oleanolic aldehyde is an antimicrobial compound effective against oral bacteria like *Streptococcus mutans* and *Porphyromonas gingivalis*, which are implicated in dental caries and periodontal disease. This compound, classified as a triterpene, is naturally derived from plants such as *Vitis vinifera* cv. Zalema.
- Antimicrobial properties
- Inhibits *Streptococcus mutans* (MIC 488 μg/mL)
- Inhibits *Porphyromonas gingivalis* (MIC 250 μg/mL)
- Demonstrates growth inhibition in B16 2F2 epithelial cells
- Exhibits antiproliferative activity against +SA mammary epithelial cells
- Plant-derived triterpene
Medchemexpress LLC Oleanolic acid 28-O-β-D-glucopyranoside | 14162-53-9 | 10 MG
Oleanolic acid 28-O-β-D-glucopyranoside is an orally active pentacyclic triterpenoid compound with anti-inflammatory effects. It can inhibit inflammatory responses, enhance intestinal epithelial barrier function, and modulate gut microbiota in ulcerative colitis models. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways. It can be used in the research of diseases such as colitis.
- Orally active pentacyclic triterpenoid compound
- Anti-inflammatory effects
- Inhibits inflammatory response
- Enhances intestinal epithelial barrier function
- Modulates gut microbiota
- Mechanism involves PI3K-AKT and MAPK signaling pathways
- Potential for research in diseases like colitis
- Purity: 99.42%
Medchemexpress LLC Urs-12-en-28-oic acid, 3-oxo- | 6246-46-4 | 454.68 | 100 MG
Ursonic acid, also known as 3-Ketoursolic acid, is a naturally occurring triterpenoid. It is orally active and has been shown to induce apoptosis in human cancer cells through multiple signaling pathways. Additionally, it exhibits both anti-inflammatory and anticarcinogenic activities.
- Orally active
- Induces apoptosis of human cancer cells
- Exhibits anti-inflammatory activity
- Exhibits anticarcinogenic activity
- High purity (99.88%)
- Solid, white to off-white appearance
- Classified as a terpenoid, triterpene, and endogenous metabolite
- Insoluble in water, soluble in DMSO
Medchemexpress LLC Ursonic acid (3-Ketoursolic acid) | 6246-46-4 | 454.68 | 50 MG
Ursonic acid, also known as 3-Ketoursolic acid, is an endogenous metabolite and a naturally occurring triterpenoid. It induces apoptosis in human cancer cells through multiple signaling pathways and exhibits anti-inflammatory and anticarcinogenic activities. This compound has been shown to protect against ethanol-mediated experimental liver injury in adult male albino rats. It is provided as a solid, white to off-white in appearance, with a purity of 99.88%. It is intended for research use only and not for human use.
- Induces apoptosis in human cancer cells.
- Possesses anti-inflammatory activity.
- Exhibits anticarcinogenic activity.
- Protects against ethanol-mediated experimental liver injury.
- High purity of 99.88%.
Medchemexpress LLC Oleanolic acid hemiphthalate disodium salt | 168770-31-8 | 98.1% | 1 ML
Oleanolic acid hemiphthalate disodium salt is a hemiphthalate derivative of Oleanolic acid, exhibiting anti-inflammatory and potential anti-ulcer activities. This product is strictly for research purposes and not for human or animal medical, clinical diagnostic, or food applications.
- Stable under recommended storage conditions.
- Soluble in DMSO, requiring sonication.
- Shows anti-inflammatory properties.
- Potential for anti-ulcer activities.
- Store solid product at 4°C, sealed, away from moisture.
- Store in solvent at -80°C for up to 6 months, or -20°C for up to 1 month.
Medchemexpress LLC Limonin (Standard) | 1180-71-8 | MFC26H30O8 | 99.1% | 470.51 | 50 MG
Limonin (Standard) is an analytical standard used for research and analytical applications. It exhibits antiviral and antitumor activities, including the inhibition of HIV-1 and induction of apoptosis in human colon adenocarcinoma cells. This standard is commonly employed in qualitative, quantitative, and methodological research experiments.
- Inhibits HIV-1 with an EC50 of 60.0 μM.
- Induces apoptosis in human colon adenocarcinoma cells with an IC50 of 54.74 μM.
- Used in HPLC, GC, and MS applications.
- Appears as a white to off-white solid.
- Classified as a terpenoid and triterpene.
- Initially sourced from plants of the Rutaceae family.
- Functions as an endogenous metabolite.
Medchemexpress LLC Limonin (standard) | 1180-71-8 | MFCD00075922 | 99.1% | 470.51 | 5 MG
Limonin (Standard) is the analytical standard of Limonin, intended for research and analytical applications. It exhibits antiviral and antitumor activities, inhibiting HIV-1 with an EC50 of 60.0 μM and inducing apoptosis in human colon adenocarcinoma cells with an IC50 of 54.74 μM. This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Inhibits HIV-1 and induces human colon adenocarcinoma cell apoptosis
- Possesses antiviral and antitumor activities
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for applications such as HPLC, GC, and MS
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 99.1% | 456.70 g/mol | C30H48O3 | 200 MG
Betulinic acid is a naturally occurring pentacyclic triterpenoid used in research as an apoptosis inducer and bioactive small molecule. It is commonly used in pharmacology and cell biology to probe apoptotic pathways, evaluate anti-inflammatory and antiviral activity, and as a scaffold for synthetic derivatization.
- Natural pentacyclic triterpenoid compound.
- Functions as an apoptosis inducer in cellular assays.
- High purity suitable for research (≈99.1%).
- Available in multiple pack sizes for screening and synthesis workflows.
- Soluble in DMSO for preparation of stock solutions.
AdipoGen Betulinic acid (>97%) (1 g)
Betulinic acid (>97%) (1 g), Adipogen Life Sciences. Chemical. CAS: 472-15-1. Formula: C30H48O3. MW: 456.7. Isolated from Platanus acerifolia bark. Anti-HIV compound. Anticancer compound. Apoptosis inducer. Modulator of NF-kappaB. Potent DNA topoisomerase II inhibitor. Potent proteasome activator. Antimalarial compound.
Cayman Chemical 23-hydroxy BetulInIc AcId 5mg
A triterpenoid with anticancer activity; inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as HUVECs (IC50 = 94.8 µM); halts the cell cycle at the S phase and induces apoptosis in K562 cells
Medchemexpress LLC 18α-Glycyrrhizic acid | 83896-44-0 | 10 MG
18α-Glycyrrhizic acid is a derivative of Glycyrrhizic acid with weak antihepatotoxic and anti-inflammatory activities. This product is for research use only.
- Purity: 99.79%.
- Appearance: Solid.
- Color: White to off-white.
- Store at -20°C, protected from light. In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
- In vitro solubility: 100 mg/mL in DMSO.
- Two in vivo dissolution protocols available.
TARGETMOL CHEMICALS INC URSONIC ACID 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor. purity: 99%
Cayman Chemical BetulInIc AcId methyl esTR 5mg
A triterpenoid and an esterified version of betulinic acid with diverse biological activities; inhibits HIV-1 reverse transcriptase (IC50 = 11 μM); active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively); induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM); cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively);
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 10mM (in 1mL DMSO), CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Cayman Chemical BetulInIc AcId 250mg
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells