Triterpenoids
Medchemexpress LLC Oleanolic aldehyde | 17020-22-3 | 440.70 | 1 MG
Oleanolic aldehyde is an antimicrobial compound effective against oral bacteria like *Streptococcus mutans* and *Porphyromonas gingivalis*, which are implicated in dental caries and periodontal disease. This compound, classified as a triterpene, is naturally derived from plants such as *Vitis vinifera* cv. Zalema.
- Antimicrobial properties
- Inhibits *Streptococcus mutans* (MIC 488 μg/mL)
- Inhibits *Porphyromonas gingivalis* (MIC 250 μg/mL)
- Demonstrates growth inhibition in B16 2F2 epithelial cells
- Exhibits antiproliferative activity against +SA mammary epithelial cells
- Plant-derived triterpene
Medchemexpress LLC Oleanolic acid 28-O-β-D-glucopyranoside | 14162-53-9 | 10 MG
Oleanolic acid 28-O-β-D-glucopyranoside is an orally active pentacyclic triterpenoid compound with anti-inflammatory effects. It can inhibit inflammatory responses, enhance intestinal epithelial barrier function, and modulate gut microbiota in ulcerative colitis models. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways. It can be used in the research of diseases such as colitis.
- Orally active pentacyclic triterpenoid compound
- Anti-inflammatory effects
- Inhibits inflammatory response
- Enhances intestinal epithelial barrier function
- Modulates gut microbiota
- Mechanism involves PI3K-AKT and MAPK signaling pathways
- Potential for research in diseases like colitis
- Purity: 99.42%
TARGETMOL CHEMICALS INC NOMILIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Nomilin is naturally occurring triterpenoids have immunomodulatory activity. purity: 97%
Medchemexpress LLC Lupeol | 545-47-1 | 426.72 | 100 MG
Lupeol is an active pentacyclic triterpenoid with anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activity. It is a potent androgen receptor (AR) inhibitor and can be used for cancer research, particularly for prostate cancer of androgen-dependent phenotype (ADPC) and castration-resistant phenotype (CRPC).
- Has anti-oxidant activity
- Has anti-mutagenic activity
- Has anti-tumor activity
- Has anti-inflammatory activity
- Potent androgen receptor (AR) inhibitor
- Can be used for cancer research
Medchemexpress LLC 18α-Glycyrrhizic acid | 83896-44-0 | 10 MG
18α-Glycyrrhizic acid is a derivative of Glycyrrhizic acid with weak antihepatotoxic and anti-inflammatory activities. This product is for research use only.
- Purity: 99.79%.
- Appearance: Solid.
- Color: White to off-white.
- Store at -20°C, protected from light. In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
- In vitro solubility: 100 mg/mL in DMSO.
- Two in vivo dissolution protocols available.
Cayman Chemical BetulInIc AcId methyl esTR 5mg
A triterpenoid and an esterified version of betulinic acid with diverse biological activities; inhibits HIV-1 reverse transcriptase (IC50 = 11 μM); active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively); induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM); cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively);
Cayman Chemical 23-hydroxy BetulInIc AcId 10mg
A triterpenoid with anticancer activity; inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as HUVECs (IC50 = 94.8 µM); halts the cell cycle at the S phase and induces apoptosis in K562 cells
AdipoGen Limonin
Chemical. CAS 1180-71-8. Formula C26H30O8. MW 470.51. Synthetic. Limonin is the first described limonoid, which are naturally occurring tetranortriterpenoids that impart bitter flavor in citrus fruits. Compounds belonging to this group have reported anti-proliferative and proapoptotic activity on several cancer cell lines as well as pesticidal, anti-malarial, anti-microbial, anti-HIV, anti-inflammatory, antinociceptive and neuroprotective activity. Shown to inhibit arginase I and II and P-glycoprotein. May be used in assays as control, standard or competitor, or in studies on the physiology, metabolism and biosynthesis of limonin.
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 10mM (in 1mL DMSO), CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Cayman Chemical 23-hydroxy BetulInIc AcId 5mg
A triterpenoid with anticancer activity; inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as HUVECs (IC50 = 94.8 µM); halts the cell cycle at the S phase and induces apoptosis in K562 cells
Medchemexpress LLC Squalane (Standard) | 111-01-3 | 500 MG
Squalane, a saturated derivative of Squalene, is found in various natural sources including fish oils and certain vegetable oils. It is recognized for its diverse biological activities, encompassing anticancer, antioxidant, skin hydrating, and emollient properties. Research indicates its potential application as a drug carrier and detoxifying agent, with observed effects in both animal models and in vitro studies.
- Purity: 98.0%
- Molecular weight: 422.83
- Formula: C30H62
- Appearance: Colorless to light yellow liquid
- Sourced from animals (fish oils)
- Storage: Pure form -20°C for 3 years, 4°C for 2 years; in solvent -80°C for 6 months, -20°C for 1 month.
- Soluble in DMSO: 100 mg/mL
Cayman Chemical 18-GlycyrrhetInIc AcId 5g
A major metabolite of glycyrrhizin, a constituent of licorice that exhibits anti-ulcerative, anti-inflammatory, and immunomodulatory properties; at 100 mg/kg/day, reduces lipid peroxidation and increases antioxidant activity in diabetic rats; suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages 100-200 μM
Medchemexpress LLC Oleanolic acid hemiphthalate disodium salt | 168770-31-8 | 98.1% | 1 ML
Oleanolic acid hemiphthalate disodium salt is a hemiphthalate derivative of Oleanolic acid, exhibiting anti-inflammatory and potential anti-ulcer activities. This product is strictly for research purposes and not for human or animal medical, clinical diagnostic, or food applications.
- Stable under recommended storage conditions.
- Soluble in DMSO, requiring sonication.
- Shows anti-inflammatory properties.
- Potential for anti-ulcer activities.
- Store solid product at 4°C, sealed, away from moisture.
- Store in solvent at -80°C for up to 6 months, or -20°C for up to 1 month.
Medchemexpress LLC Urs-12-en-28-oic acid, 3-oxo- | 6246-46-4 | 454.68 | 100 MG
Ursonic acid, also known as 3-Ketoursolic acid, is a naturally occurring triterpenoid. It is orally active and has been shown to induce apoptosis in human cancer cells through multiple signaling pathways. Additionally, it exhibits both anti-inflammatory and anticarcinogenic activities.
- Orally active
- Induces apoptosis of human cancer cells
- Exhibits anti-inflammatory activity
- Exhibits anticarcinogenic activity
- High purity (99.88%)
- Solid, white to off-white appearance
- Classified as a terpenoid, triterpene, and endogenous metabolite
- Insoluble in water, soluble in DMSO
Apexbio Technology LLC Limonin 1180-71-8 200mg
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models