Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Sigma Aldrich Fine Chemicals Biosciences Formic acid ACS reagent, 88-91, 64-18-6, MFCD00003297
Formic acid ACS reagent, 88-91
Medchemexpress LLC Ivaltinostat (formic) | 98.3% | 473.56 | 1 MG
Ivaltinostat formic is an orally active, potent pan-HDAC inhibitor that features a hydroxamic acid moiety designed to bind zinc at the catalytic pocket. It inhibits deacetylation of histone H3 and tubulin, inducing p53 accumulation and promoting p53-dependent transactivation. This compound enhances the expression of MDM2 and p21 proteins, increases sensitivity of Gemcitabine-resistant cells to therapies, induces apoptosis, and demonstrates anti-tumour effects.
- Potent pan-HDAC inhibitor
- Inhibits deacetylation of histone H3 and tubulin
- Promotes p53-dependent transactivation
- Enhances expression of MDM2 and p21 proteins
- Increases sensitivity of drug-resistant cells
- Induces apoptosis
- Exhibits anti-tumour effects
- Attenuates oxidative stress and inflammation
Jade Scientific, Inc Formic acid, 50ml, 64-18-6
Formic acid. For mass spectrometry, ca. 98%~98%. Glass Bottle. For Research Only
Sigma Aldrich Fine Chemicals Biosciences Formic acid, 64-18-6, MFCD00003297, 500 mL
Linear Formula: HCOOH, Molecular Weight: 46.03, puriss., meets analytical specifications of DAC, FCC, 98.0-100%.
Sigma Aldrich Fine Chemicals Biosciences Formic acid puriss. p.a., ACS reagent, reag. Ph. Eur., >=98% | 64-18-6 | MFCD00003297 | 500ML
Formic acid puriss. p.a., ACS reagent, reag. Ph. Eur., >=98% | Purity: >=98% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 500ML
Medchemexpress LLC Lcc-12 formic | 3029253-76-4 | 99.2% | 460.57 g/mol | C18H40N10O4 | 10 MG
LCC-12 formic is a research-grade small molecule probe (a dimer of metformin) used to modulate mitochondrial copper(II) and study inflammation and metabolic pathways in cellular and animal models.
- Targets mitochondrial copper(II) and reduces the NAD(H) pool.
- Reduces inflammation in mouse models of bacterial and viral infection.
- Serves as a tool to study metabolic disease, cell plasticity, and epigenetic programming.
- High purity and characterized molecular properties for reliable experimental use.
- Compatible with storage at -20°C; in solution store at -80°C for long-term stability.
Medchemexpress LLC 5-Propargyltryptamide formic | 2906227-87-8 | 99.9% | 260.29 g/mol | C14H16N2O3 | 10 MG
5-PT formic (5-Propargyltryptamide formic) is a serotonin-derived chemical probe containing a propargyl (alkyne) moiety for copper-catalyzed azide-alkyne cycloaddition (click chemistry). It is used to label and study protein serotonylation in biochemical and cell-based assays.
- Enables copper-catalyzed click chemistry labeling of serotonylated proteins.
- High chemical purity (99.91%).
- Solid, white to off-white physical form for easy handling and storage.
- Suitable for biochemical and cell-based assay applications.
- Available in small-scale quantities (for example, 10 mg) for exploratory studies.
Medchemexpress LLC Slb1122168 formic | 2999629-17-1 | 99.9% | 403.56 | C23H37N3O3 | 10 MG
SLB1122168 formic is a research-stage small molecule that inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release. It has reported in vitro potency and is supplied for laboratory research with recommended storage and handling per the Safety Data Sheet.
eMolecules 64-18-6 | Formic Acid, ACS Grade | Oakwood Chemicals | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 2.5kg | 480143864
Formic Acid, ACS Grade | Oakwood Chemicals | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 2.5kg | 480143864
Medchemexpress LLC CBI1 formic | 461.40 | C16H21BrN4O3S2 | 10 MG
CBI1 formic is a covalent small-molecule inhibitor of BAX that selectively derivatizes the protein at cysteine 126 (C126), preventing BAX activation. Supplied for research use, structural and storage information is provided by the manufacturer.
- Covalent BAX inhibitor that derivatizes C126.
- Inhibits BAX activation induced by ligands or point mutations.
- Offered as a solid with sealed, moisture-free storage recommendations.
- Molecular formula C16H21BrN4O3S2; molecular weight 461.40.
- Available in small research pack sizes, including 10 mg.
- Intended for research use only; not for human or clinical use.
eMolecules 64-18-6 | Formic Acid, ACS Grade | Oakwood Chemicals | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 20kg | 480143866
Formic Acid, ACS Grade | Oakwood Chemicals | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 20kg | 480143866