Gallic Acid
Medchemexpress LLC Afimetoran (BMS-986256) | 2171019-55-7 | 99.4% | 444.57 | 50 MG
Afimetoran (BMS-986256) is an orally active, selective, and highly bioavailable antagonist of Toll-like Receptor 7 and 8 (TLR7/8). It operates by inhibiting the activation of the NF-κB pathway, which is crucial in immune responses. Furthermore, Afimetoran can reverse TLR7-mediated resistance to steroid-induced apoptosis in plasma cell-like dendritic cells (pDCs). This compound is valuable for research into inflammation and autoimmune diseases, such as systemic lupus erythematosus.
- Orally active
- Selective TLR7/8 antagonist
- Highly bioavailable
- Inhibits NF-κB pathway
- Reverses steroid resistance
- Research applications
- Demonstrated in vivo efficacy
![eMolecules 2165347-55-5 | {3-PHENYLBICYCLO[1.1.1]PENTAN-1-YLMETHANOL | AstaTech174.243 | C12H14O | 95.000 | OCC12CC(C1)(C2)c1ccccc1 | 0.1g | 528990179](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502480950.JPG-250.jpg)
eMolecules 2165347-55-5 | {3-PHENYLBICYCLO[1.1.1]PENTAN-1-YLMETHANOL | AstaTech174.243 | C12H14O | 95.000 | OCC12CC(C1)(C2)c1ccccc1 | 0.1g | 528990179
{3-PHENYLBICYCLO[1.1.1]PENTAN-1-YLMETHANOL | AstaTech | 2165347-55-5174.243 | C12H14O | 95.000 | OCC12CC(C1)(C2)c1ccccc1 | 0.1g | 528990179
eMolecules 1420-55-9 | Medchem Express | Thiethylperazine | 5mg | 721611168 | HY-B1794 | MFCD00865537 | 399.62 | C22H29N3S2
Medchem Express | MBP146-78 | 1mg | 446256967 | HY-101525 | 188343-77-3 | MFCD30474871 | 335.426 | C21H22FN3
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eMolecules 1798310-55-0 | Medchem Express | AR420626 | 5mg | 713705765 | HY-116522 | MFCD28987470 | 417.29 | C21H18Cl2N2O3
Medchem Express | TNF--IN-6 | 1mg | 761041060 | HY-142618 | 2699704-20-4 | 495.547 | C26H25N9O2
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eMolecules 1384966-55-5 | Ambeed | Di(adamantan-1-yl)(2-((triisopropylsilyl)oxy)phenyl)phosphine | 100mg | 672837994 | A1168687 | 550.883 | C35H55OPSi
Ambeed | 4-(2H-123-Triazol-2-yl)benzaldehyde | 250mg | 525039419 | A133650 | 179056-04-3 | MFCD08669904 | 173.175 | C9H7N3O
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Medchemexpress LLC 2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-n-(1,3,5-trimethyl-1h-pyrazol-4-yl)benzenesulfonamide | 1215010-55-1 | 99.7% | 495.43 g/mol | C21H24Cl2N6O2S | 5 MG
2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide is a small-molecule N-myristoyltransferase (NMT) inhibitor with potent enzymatic and cellular activity against Trypanosoma brucei. It demonstrates nanomolar potency and is supplied in solid and DMSO solution formulations for research use.
- Potent NMT inhibition; TbNMT IC50 = 2 nM, hNMT IC50 = 4 nM.
- Orally active in preclinical models.
- High purity (≈99.7%) suitable for biochemical assays.
- Available as solids and DMSO solutions for assay flexibility.
- Useful for parasite biology and antitrypanosomal drug discovery research.
eMolecules 678158-55-9 | Medchem Express | CLZ-8 | 5mg | 506403843 | HY-122627 | MFCD04091440 | 393.51 | C22H23N3O2S
Medchem Express | CLZ-8 | 5mg | 506403843 | HY-122627 | 678158-55-9 | MFCD04091440 | 393.510 | C22H23N3O2S
Medchemexpress LLC Gallic acid (3,4,5-Trihydroxybenzoic acid) | 149-91-7 | 170.12 | 25 MG
Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and a free radical scavenger that inhibits cyclooxygenase-2 (COX-2). It has various activities such as antimicrobial, antioxidant, anti-inflammatory, and anticancer properties.
- Natural polyhydroxyphenolic compound
- Free radical scavenger to inhibit cyclooxygenase-2 (COX-2)
- Antimicrobial activity
- Antioxidant activity
- Anti-inflammatory activity
- Anticancer activity
Medchemexpress LLC Eteplirsen | 1173755-55-9 | 98.5% | 10306.00 | 1 ML
Eteplirsen (AVI 4658) is a synthetic antisense oligonucleotide. It is used for Duchenne muscular dystrophy research. It promotes dystrophin production by restoring the translational reading frame of Duchenne muscular dystrophy (DMD) through specific skipping of exon 51 in defective gene variants.
- Synthetic antisense oligonucleotide
- Can be used for Duchenne muscular dystrophy research
- Promotes dystrophin production by restoring the translational reading frame through specific skipping of exon 51
Hach Company Gallic Acid Solution, 50 mL SCDB
Gallic acid Solution for conductivity testing. Used to neutralize hydroxide ion interference.
