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Malic acid, an organic dicarboxylic acid with two stereoisomeric forms, plays an important biochemical role in both the Calvin cycle and the citric acid cycle. It is used as a food additive and preservative, a therapeutic agent, and a dietary supplement.
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(S)-Malic acid (Standard) is the analytical standard of (S)-Malic acid This product is intended for research and analytical applications (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form contributes to the pleasantly sour taste of fruits and is used as a food additive In Vitro It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L casei Furthermore deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid thus indicating that the cognate TC system regulates and is essential for the expression of ME Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose[1]
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Malic acid disodium hydrate is the disodium salt hydrate form of malic acid intended for laboratory biochemical and buffering applications. It is a white to off-white powder with high water solubility and is supplied in small packs for laboratory use. The reagent is documented with storage and solubility data suited for assay workflows.
Disodium salt hydrate form of malic acid, useful as a buffer and biochemical reagent.
High purity: 98.0% suitable for analytical and assay work.
Water soluble: approximately 175 mg/mL (may require ultrasonic assistance).
Stable at room temperature when stored under nitrogen and away from moisture; extended storage in solvent at -20°C to -80°C.
Supplied in small laboratory pack sizes for convenient handling.
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D-(+)-Malic acid, also known as D-Malic acid, is an active enantiomer of Malic acid. It serves as a competitive inhibitor of L-(-)malic acid transport. This product is an analytical standard of D-(+)-Malic acid, specifically intended for research and analytical applications.
Competitive inhibitor of L-(-)malic acid transport
Suitable for research and analytical applications
Enantiomer of Malic acid
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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective brain-penetrant and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic acid) can be used in studies about PD Parkinson’s disease SRT in Fabry’s and Gaucher’s. purity: 99%
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Malate dehydrogenase (EC 1.1.1.37) (MDH) catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes.
Michaelis constant: 1.5x10-6 M (NADH, 37°C), 1.9x10-6 M (oxaloacetate, 37°C)
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(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form contributes to the pleasantly sour taste of fruits and is used as a food additive
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Malate dehydrogenase (MDH), also known as EC 1.1.1.37, catalyzes the reversible interconversion of oxaloacetate and malate, playing a crucial role in metabolic pathways involving the oxidation/reduction of dinucleotide coenzymes.
Enzymatic activity: ≥10 U/mg solid
Molecular weight: approximately 35,000
Michaelis constant: 1.5x10⁻⁶ M (NADH, 37°C); 1.9x10⁻⁶ M (oxaloacetate, 37°C)