Acyl bromides
Medchemexpress LLC (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose | 6612-91-5 | 95.1% | 294.30 | 1 ML
(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is a purine nucleoside analog. Purine nucleoside analogs exhibit broad antitumor activity, specifically targeting indolent lymphoid malignancies. The anticancer mechanisms associated with this process include inhibition of DNA synthesis and induction of apoptosis.
- Appearance: solid
- Color: white to off-white
- Shipping: room temperature in continental US; may vary elsewhere
- Storage: powder: -20°C for 3 years, 4°C for 2 years; in solvent: -80°C for 6 months, -20°C for 1 month
- Purine nucleoside analog
- Broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC Oleyl bromide ((Z)-1-Bromooctadec-9-ene) | 6110-53-8 | 98.4% | 331.37 | 500 MG
Oleyl bromide ((Z)-1-Bromooctadec-9-ene) is a hydrophobic compound that can carry out ring-opening reactions through a process called "encapsulation." It can also be used as the starting material in the synthesis of oleylphosphonates.
- Hydrophobic compound
- Used in ring-opening reactions
- Starting material for the synthesis of oleylphosphonates
- Appears as a liquid
- Colorless to light yellow in color
Medchemexpress LLC 1,3,5-tri-O-benzoyl-α-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 100 G
1,3,5-Tri-O-benzoyl-α-D-ribofuranose is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This product is intended for research use only and is not sold to patients.
- Targets nucleoside antimetabolite/analog pathways.
- Involved in cell cycle/DNA damage pathways.
- Soluble in DMSO at 100 mg/mL (216.24 mM), requiring ultrasonication.
- Powder is stable for 3 years at -20°C and 2 years at 4°C.
- In solvent, stable for 6 months at -80°C and 1 month at -20°C.
Medchemexpress LLC KRN2 bromide | 1390654-28-0 | 98.8% | 524.38 | 25 MG
KRN2 bromide is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6. It also dose-dependently inhibits NF-κB p65 binding to Nfat5 promoter 1 and directly blocks the interaction between NF-κB p65 and its DNA binding sequence.
- Selectively inhibits nuclear factor of activated T cells (NFAT5).
- Suppresses expression of pro-inflammatory genes.
- Inhibits NF-κB p65 binding to Nfat5 promoter.
- Effectively suppresses AIA and CIA in mice, decreasing pro-inflammatory cytokines and autoantibodies.
Medchemexpress LLC Biotin-PEG3-bromide | 1041766-91-9 | 95.0% | 482.43 g·mol⁻1 | C18H32BrN3O5S | 25 MG
Biotin-PEG3-bromide is a biotinylated short polyethylene glycol (PEG3) linker with a terminal alkyl bromide. It is used to introduce a biotin affinity tag onto molecules via nucleophilic substitution or cross-coupling reactions, enabling streptavidin-based capture, detection, and pull-down workflows in chemical biology and bioconjugation studies.
- Reactive alkyl bromide suitable for nucleophilic substitution and cross-coupling reactions.
- Biotin moiety enables high-affinity capture with streptavidin/avidin reagents.
- Short PEG3 spacer improves solubility and reduces steric hindrance.
- High solubility in DMSO allows preparation of concentrated stock solutions.
- Powder stable at -20°C; follow recommended storage for solutions to maintain integrity.
Medchemexpress LLC N-Benzoyl-(2R,3S)-3-phenylisoserine | 132201-33-3 | 5 MG
N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain that is crucial for the strong antitumor activity of Taxol.
- Purity of 99.48%
- Appearance as a white to off-white solid
- Soluble in DMSO at ≥ 160 mg/mL (560.83 mM)
Medchemexpress LLC Aclidinium bromide | 320345-99-1 | MFCD22683690 | 99.0% | C26H30BrNO4S2 | 10MG
Aclidinium bromide is a long-acting inhaled muscarinic antagonist used in respiratory research, primarily for studies of chronic obstructive pulmonary disease (COPD) and muscarinic receptor function. Supplied as the bromide salt with characterized identity and high purity, it is intended for in vitro and preclinical pharmacology applications.
- Long-acting muscarinic antagonist for COPD and airway research.
- High purity suitable for analytical and pharmacological studies.
- Available as solid and DMSO solution formats for flexible use.
- Well-characterized chemical identity and molecular data.
- Useful as a pharmacological tool to probe muscarinic receptor-mediated bronchodilation.
Medchemexpress LLC N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine | 64325-78-6 | 98.0% | 657.71 | 1 ML
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine serves as an intermediate in various chemical processes. It is intended for research use only and is not sold to patients.
- Used as a chemical intermediate.
- High purity of 98.0%.
- Available in different forms including solid and a 10 mM solution in DMSO.
- Detailed solubility information and stock solution preparation guidance provided.
- Comprehensive documentation including Data Sheet, COA, SDS, and Handling Instructions.
Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-25mg
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2
eMolecules Oakwood Chemicals Copper(II) bromide 2 5kg 480169542 BR1147 0 000 7789-45-9 MFCD00010970 223 354 Br2Cu
Oakwood Chemicals Copper(II) bromide 2 5kg 480169542 BR1147 0 000 7789-45-9 MFCD00010970 223 354 Br2Cu
Apexbio Technology LLC Tiotropium Bromide hydrate 139404-48-1 10mg
Tiotropium Bromide hydrate is a small-molecule antagonist targeting muscarinic acetylcholine receptors (mAChRs) It is designed to competitively inhibit mAChRs thereby modulating airway smooth muscle contraction and mediating bronchodilation Tiotropium Bromide hydrate exerts its biological activity primarily through competitive antagonism at mAChRs resulting in relaxation of airway smooth muscle Based on these pharmacological properties Tiotropium Bromide hydrate holds research potential in respiratory pharmacology particularly for investigating mechanistic pathways in chronic obstructive pulmonary disease (COPD) receptor-ligand interactions and pulmonary pharmacodynamics associated with airway obstruction
Apexbio Technology LLC Rocuronium Bromide 119302-91-9 10mM (in 1mL DMSO)
Rocuronium Bromide (CAS 119302-91-9) is an aminosteroid compound that functions as a non-depolarizing neuromuscular blocking agent It acts by competitively antagonizing nicotinic acetylcholine receptors at the neuromuscular junction thereby inhibiting acetylcholine-induced depolarization and subsequent muscle contraction In research settings Rocuronium Bromide is utilized to investigate neuromuscular transmission and to model pharmacological blockade of skeletal muscle activity supporting studies in anesthesia muscle physiology and synaptic transmission mechanisms
Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | MFCD18782614 | 508.49 | 1 G
Umeclidinium bromide is a novel mAChR antagonist, demonstrating high affinity for cloned human M1-M5 mAChRs with Ki values ranging from 0.05 to 0.16 nM. It is a potent agent that exhibits slow functional reversibility at cloned human M3 mAChRs and endogenous mAChRs in isolated human bronchus. This compound is suitable for research in various disease areas including neurological, eye or ear disease, cancer, inflammation or immune system disease, neurodegenerative disease, and Parkinson's disease.
- Novel mAChR antagonist
- High affinity for human M1-M5 mAChRs (Ki 0.05-0.16 nM)
- Inhibits human ether-a-go-go-related gene channel tail current with an IC50 of 9.4 μM
- Demonstrates slow functional reversibility at human M3 mAChRs
- Applicable for research in neurological, ocular, oncological, inflammatory, and neurodegenerative conditions
Medchemexpress LLC Pinaverium bromide | 53251-94-8 | 99.7% | 591.42 | 5.9 MG
Pinaverium bromide is an L-type calcium channel blocker that selectively targets the gastrointestinal tract. It is effective in relieving pain, diarrhea, and intestinal discomfort, providing therapeutic benefits for patients with Irritable Bowel Syndrome (IBS) without significant adverse effects.
- L-type calcium channel blocker
- Gastrointestinal selectivity
- Symptom relief for pain, diarrhea, and intestinal discomfort
- Therapeutic for Irritable Bowel Syndrome patients
- Favorable safety profile
eMolecules 4-(Bromoacetyl)pyridine hydrobromide | Combi-Blocks | 5349-17-7 | MFCD02681893 | 280.947 | C7H7Br2NO | 90.000 | Br.BrCC(=O)c1ccncc1 | 5g | 249357428
4-(Bromoacetyl)pyridine hydrobromide | Combi-Blocks | 5349-17-7 | MFCD02681893 | 280.947 | C7H7Br2NO | 90.000 | Br.BrCC(=O)c1ccncc1 | 5g | 249357428