Acyl bromides
Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-10mM/1mL
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2
Sigma Aldrich Fine Chemicals Biosciences Nalpha-Benzoyl-L-arginine25MG
NBenzoyl-L-arginine 4-nitroanilide hydrochloride is a substrate for trypsin.
Apexbio Technology LLC Umeclidinium bromide 869113-09-7 50mg
Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
Medchemexpress LLC Tiotropium (Bromide) | 136310-93-5 | 99.9% | 472.42 | 100 MG
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and the subsequent opening of the ligand-gated ion channel. It is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). It has also been shown to improve symptoms of COPD complicated by chronic heart failure.
- Muscarinic acetylcholine receptor (mAChR) antagonist
- Blocks binding of acetylcholine ligand and opening of ligand-gated ion channel
- Stops signaling between neurons leading to muscle relaxation
- Long-acting, 24-hour anticholinergic bronchodilator
- Used in the management of chronic obstructive pulmonary disease (COPD)
- Improves symptoms of COPD complicated by chronic heart failure
- For research use only
Medchemexpress LLC Otilonium bromide | 26095-59-0 | 99.7% | 25 MG
Otilonium bromide | 26095-59-0 | 99.7% | 25 MG
Medchemexpress LLC 1,3,5-Tri-O-benzoyl-a-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 10 G
1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog that exhibits broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis.
- Purine nucleoside analog
- Broad antitumor activity
- Inhibits DNA synthesis
- Induces apoptosis
- For research use only
Medchemexpress LLC 1,3,5-Tri-O-benzoyl-a-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 5 G
1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis, among other processes.
- Purine nucleoside analog
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
- Useful for cancer research
Medchemexpress LLC Fentonium bromide | 5868-06-4 | 98.8% | 10MM 1ML
Fentonium bromide | 5868-06-4 | 98.8% | 10MM 1ML
TARGETMOL CHEMICALS INC Clidinium bromide 500MG
Also available in 1 mL, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can inhibit muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also to help relieve cramps or stomach spasms or abdominal due to colicky abdominal diverticulitis, pain, and irritable bowel syndrome. Purity 99.36%
Apexbio Technology LLC Mepenzolate Bromide 76-90-4 500mg
Mepenzolate bromide (CAS 76-90-4) is a synthetic quaternary ammonium compound that functions as a muscarinic acetylcholine receptor antagonist By inhibiting parasympathetic neural transmission it reduces gastric secretion and gastrointestinal motility Mepenzolate bromide is generally supplied as a white to light cream powder with high solubility in methanol limited solubility in water and chloroform and minimal solubility in ether This compound is widely employed in research investigating modulation of cholinergic signaling gastrointestinal physiology and autonomic pharmacology and serves as a tool compound for studying antimuscarinic mechanisms in vitro and in vivo
Medchemexpress LLC Tiotropium (Bromide) | 136310-93-5 | 99.9% | 472.42 | 50 MG
Tiotropium (Bromide) | 136310-93-5 | 99.9% | 472.42 | 50 MG
Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | 99.1% | 50 MG
Umeclidinium bromide is a potent muscarinic acetylcholine receptor antagonist used for receptor pharmacology and binding studies. It is supplied as a white to off-white solid appropriate for analytical and research applications.
- Potent mAChR antagonist with Ki 0.05-0.16 nM.
- High purity suitable for analytical and assay applications.
- Chemical formula C29H34BrNO2; molecular weight 508.49.
- Available in small lab pack sizes for research use.
Selleck Chemical LLC Rocuronium Bromide S1397-10mg
Rocuronium Bromide (ORG 9426) is a competitive AchR antagonist used in modern anaesthesia
Medchemexpress LLC Fentonium bromide | 5868-06-4 | 98.8% | 50MG
Fentonium bromide | 5868-06-4 | 98.8% | 50MG