Halomethanes
Medchemexpress LLC BAY-593 | 2413020-56-9 | 99.9% | 476.53 | 50 MG
BAY-593 is an orally active GGTase-I inhibitor that can block YAP1/TAZ signaling in animals and exhibits antitumor activity. It is for research use only.
- Orally active GGTase-I inhibitor.
- Blocks YAP1/TAZ signaling in animals.
- Possesses antitumor activity.
- Inhibits the proliferation of HT-1080 and MDA-MB-231 cells with IC50 values of 0.038 and 0.564 μM, respectively, in vitro.
- Shows dose-dependent antitumor activity in HT-1080 fibrosarcoma and MDA-MB-231 triple-negative breast cancer xenotransplantation mouse models in vivo.
![eMolecules 91159-88-5 | 1H-BENZO[D][1,2,3]TRIAZOLE-6-SULFONIC ACID | AstaTech199.180 | C6H5N3O3S | 97.000 | OS(=O)(=O)c1ccc2nn[nH]c2c1 | 0.25g | 444389076](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502486787.JPG-250.jpg)
eMolecules 91159-88-5 | 1H-BENZO[D][1,2,3]TRIAZOLE-6-SULFONIC ACID | AstaTech199.180 | C6H5N3O3S | 97.000 | OS(=O)(=O)c1ccc2nn[nH]c2c1 | 0.25g | 444389076
1H-BENZO[D][1,2,3]TRIAZOLE-6-SULFONIC ACID | AstaTech | 91159-88-5199.180 | C6H5N3O3S | 97.000 | OS(=O)(=O)c1ccc2nn[nH]c2c1 | 0.25g | 444389076
Medchemexpress LLC MPP+ iodide | 36913-39-0 | 100.0% | 297.14 | 50 MG
MPP+ iodide is a toxic metabolite of the neurotoxin MPTP. It causes symptoms of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in the substantia nigra. It is taken up by the dopamine transporter into dopaminergic neurons, where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high-affinity substrate for the serotonin transporter (SERT).
- Toxic metabolite of neurotoxin MPTP.
- Causes Parkinson's disease symptoms in animal models.
- Selectively destroys dopaminergic neurons in substantia nigra.
- Taken up by dopamine transporter into dopaminergic neurons.
- Exerts neurotoxic action on mitochondria by affecting complex I of the respiratory chain.
- High-affinity substrate for the serotonin transporter (SERT).
Medchemexpress LLC Bay-593 | 2413020-56-9 | 99.9% | 476.53 g/mol | C26H31F3N2O3 | 10 MG
BAY-593 is an orally active geranylgeranyltransferase-I (GGTase-I) inhibitor that blocks YAP1/TAZ signaling and demonstrates antitumor activity in animal models. It is used as a research probe to study Rho-GTPase prenylation, YAP1/TAZ-dependent pathways, and related cancer biology applications.
- Orally active GGTase-I inhibitor suitable for in vivo studies.
- Blocks YAP1/TAZ signaling in cells and animals.
- Demonstrates antitumor activity in animal models.
- High purity solid form for research applications.
- Available in small research pack sizes and as a DMSO solution for screening.
eMolecules 593-71-5 | Chloroiodomethane | Apollo Scientific | MFCD00001078 | 176.380 | CH2ClI | 97.000 | ClCI | 100g | 771340366
Chloroiodomethane | Apollo Scientific | 593-71-5 | MFCD00001078 | 176.380 | CH2ClI | 97.000 | ClCI | 100g | 771340366
Sigma Aldrich Fine Chemicals Biosciences Carbon tetrachloride | 56-23-5 | MFCD00000785 | 1L
Carbon tetrachloride | Purity: ≥99.9% | MW:153.82 | 56-23-5 | MFCD00000785 | 1L
Sigma Aldrich Fine Chemicals Biosciences Iodomethane Pharmaceutical
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Medchemexpress LLC Inaxaplin (VX-147) | 2446816-88-0 | 99.4% | C21H18F3N3O3 | 10MG
Inaxaplin (VX-147) is an orally active small-molecule inhibitor of apolipoprotein L1 (APOL1) channel function, developed for research into APOL1-mediated kidney disease. It is supplied for laboratory research as a high-purity solid or as a DMSO solution.
![Medchemexpress LLC 3-{[(3,4-dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid | 199735-88-1 | MFCD00167693 | >98.0% | 326.17 g·mol⁻¹ | C15H13Cl2NO3 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242454.png-250.jpg)
Medchemexpress LLC 3-{[(3,4-dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid | 199735-88-1 | MFCD00167693 | >98.0% | 326.17 g·mol⁻¹ | C15H13Cl2NO3 | 50 MG
CADD522 is a small-molecule inhibitor of RUNX2-DNA binding used in research to downregulate RUNX2-mediated transcription. It has demonstrated antiproliferative and antimetastatic effects in cell-based and animal cancer studies and is supplied as a solid for laboratory use.
- Inhibits RUNX2-DNA binding with reported IC50 ≈ 10 nM.
- Demonstrated activity in in vitro and in vivo cancer models.
- High purity appropriate for biochemical and cell-based assays.
- Provided in small research quantities for screening and mechanistic studies.
- Stable solid form; store at -20 °C under recommended conditions.
Apexbio Technology LLC RNA Stabilization Solution for Animal Tissue 100mL
RNA Stabilization Solution for Animal Tissue is a reagent designed to stabilize RNA within animal tissues and cells It works by rapidly penetrating tissue and effectively inhibiting RNase enzymes thereby preventing RNA degradation This enables preservation of RNA integrity at ambient temperatures post-collection eliminating the need for immediate snap-freezing in liquid nitrogen Based on these properties RNA Stabilization Solution for Animal Tissue is suitable for preserving RNA expression profiles in animal tissue samples during collection transport and storage supporting downstream applications such as transcriptome analysis and quantitative gene expression studies
Sigma Aldrich Fine Chemicals Biosciences Iodomethane contains copper as stabilizer, ReagentPlus(R), 99% | 74-88-4 | MFCD00001073 | 4X100G
Iodomethane contains copper as stabilizer, ReagentPlus(R), 99% | Purity: 99% | Mol Wt: 141.94 | 74-88-4 | MFCD00001073 | 4X100G
Sigma Aldrich Fine Chemicals Biosciences Iodomethane contains copper as stabilizer, ReagentPlus(R), 99% | 74-88-4 | MFCD00001073 | 25KG
Iodomethane contains copper as stabilizer, ReagentPlus(R), 99% | Purity: 99% | Mol Wt: 141.94 | 74-88-4 | MFCD00001073 | 25KG
eMolecules 832695-88-2 | 3-(METHYLCARBAMOYL)BENZENEBORONIC ACID | AstaTech | MFCD04038918 | 178.980 | C8H10BNO3 | 95.000 | CNC(=O)c1cccc(c1)B(O)O | 1g | 448261347
3-(METHYLCARBAMOYL)BENZENEBORONIC ACID | AstaTech | 832695-88-2 | MFCD04038918 | 178.980 | C8H10BNO3 | 95.000 | CNC(=O)c1cccc(c1)B(O)O | 1g | 448261347