Halomethanes
Medchemexpress LLC Chi-KAT8i5 | 2839860-29-4 | 98.0% | 10 MG
CHI-KAT8i5 is a selective, orally active inhibitor of KAT8 (lysine acetyltransferase 8) designed for oncology research. It shows measurable binding to KAT8, inhibits proliferation of esophageal cancer cell lines in vitro, induces dose-dependent apoptosis, and has demonstrated tumor growth suppression in xenograft models.
- Selective KAT8 inhibition with a measured KD of 19.72 μM.
- Cellular antiproliferative activity (IC50 2-3 μM) in esophageal cancer cell lines.
- Induces dose-dependent apoptosis in treated cells.
- Reduces H4K16ac and c-Myc levels in cellular assays.
- Demonstrated oral activity and tumor growth suppression in vivo.
- High DMSO solubility (100 mg/mL) and defined storage recommendations.
eMolecules 1415236-88-2 | Ambeed | 2-(4-(Allyloxy)phenyl)-4455-tetramethyl-132-dioxaborolane | 250mg | 724427520 | A473555 | MFCD20491433 | 260.14 | C15H21BO3
Ambeed | 1-(7-Methyl-2-phenylimidazo[12-a]pyridin-3-yl)-2-phenylethane-12-dione | 1mg | 598441743 | A1216693 | 1850276-58-2 | 340.382 | C22H16N2O2
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eMolecules 89318-88-7 | Medchem Express | Thymopentin (acetate) | 5mg | 515744480 | HY-N7122A | MFCD00133107 | 739.828 | C32H53N9O11
Medchem Express | Thymopentin (acetate) | 5mg | 515744480 | HY-N7122A | 89318-88-7 | MFCD00133107 | 739.828 | C32H53N9O11
Medchemexpress LLC TMPyP tetrachloride 10mg
TMPyP tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC CCL4 Mouse 10ug
Recombinant mouse CCL4 (C-C motif chemokine ligand 4) is a proinflammatory chemokine expressed in E. coli and supplied lyophilized for research use. It promotes leukocyte chemotaxis, acts as a monokine that can form homodimers, and is provided with high purity suitable for in vitro studies of inflammation and immune cell migration.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Recombinant expression in E. coli without affinity tag.
- Supplied lyophilized from buffered formulation for stability.
- Predicted molecular mass ~7.8 kDa (observed ~5-10 kDa by SDS-PAGE).
- Intended for in vitro research applications studying chemotaxis and inflammation.
- Stable when aliquoted and stored at -20°C or -80°C for extended storage.
Medchemexpress LLC CHI-KAT8i5 | 2839860-29-4 | 98.00% | 523.69 | 5 MG
CHI-KAT8i5 is a selective, orally active KAT8 inhibitor that induces cancer cell apoptosis and suppresses esophageal squamous cell carcinoma (ESCC) growth by targeting the KAT8/c-Myc signaling pathway. It demonstrates high specificity and anti-proliferative effects in vitro and in vivo.
- Selective, orally active KAT8 inhibitor
- High specificity; does not bind to other HAT family proteins
- Induces cancer cell apoptosis
- Suppresses esophageal squamous cell carcinoma (ESCC) growth
- Targets KAT8/c-Myc signaling pathway
- Demonstrates in vitro anti-proliferative effects against KYSE 30 and KYSE 150 cells
- Represses NPM1 and PPAT transcript expression; decreases H4K16ace and c-Myc levels
- Effective in vivo in suppressing ESCC tumor growth
- Reduces Ki-67, c-Myc expression, and H4K16ace levels in vivo
Sigma Aldrich Fine Chemicals Biosciences Dibromomethane-d2 >=99 atom % D, >=99% (CP), contains copper as stabilizer | 22117-86-8 | MFCD00000169 | 5G
Dibromomethane-d2 >=99 atom % D, >=99% (CP), contains copper as stabilizer | Purity: >=99% (CP) | Mol Wt: 175.85 | 22117-86-8 | MFCD00000169 | 5G
Sigma Aldrich Fine Chemicals Biosciences Dichloromethane suitable f1L
Dichloromethane has been tested as a solvent medium for dipyridine-chromium(VI) oxide. Solubility was reported to be 12.5g/100ml. Role of the quantity of TiO2 loading on activated carbon support on dichloromethane photodecomposition has been investigated.
eMolecules 593-71-5 | Chloroiodomethane | Combi-Blocks | MFCD00001078 | 176.380 | CH2ClI | 98.000 | ClCI | 100g | 117541119
Chloroiodomethane | Combi-Blocks | 593-71-5 | MFCD00001078 | 176.380 | CH2ClI | 98.000 | ClCI | 100g | 117541119
eMolecules 558-13-4 | Carbon tetrabromide | Oakwood Chemicals | MFCD00000117 | 331.627 | CBr4 | 99.000 | BrC(Br)(Br)Br | 100g | 480153918
Carbon tetrabromide | Oakwood Chemicals | 558-13-4 | MFCD00000117 | 331.627 | CBr4 | 99.000 | BrC(Br)(Br)Br | 100g | 480153918
eMolecules 558-13-4 | Carbon tetrabromide | Oakwood Chemicals | MFCD00000117 | 331.627 | CBr4 | 99.000 | BrC(Br)(Br)Br | 1g | 480153915
Carbon tetrabromide | Oakwood Chemicals | 558-13-4 | MFCD00000117 | 331.627 | CBr4 | 99.000 | BrC(Br)(Br)Br | 1g | 480153915