Halomethanes
Apexbio Technology LLC 360A iodide 737763-37-0 10mg
360A iodide (CAS 737763-37-0) is a 2 6-pyridine-dicarboxamide derivative that acts as a selective ligand for G-quadruplex DNA structures By stabilizing telomeric G-quadruplexes 360A inhibits telomerase activity and induces alterations in cell cycle progression notably causing S-phase accumulation in ATM-proficient EBV-lymphocytes Its mechanism of action involves promoting sister telomere fusions via DNA-PKcs-dependent non-homologous end joining (NHEJ) as well as triggering NHEJ and homologous recombination (HR) pathways at telomeres which disrupt mitotic progression 360A has been shown to preferentially bind telomeric G-quadruplex DNA over duplex DNA and to delay growth in HT1080 tumor cells This compound is valuable for investigating telomere biology DNA damage response and G-quadruplex-mediated genomic stability
Medchemexpress LLC BAY-593 | 2413020-56-9 | 99.9% | 476.53 | 50 MG
BAY-593 is an orally active GGTase-I inhibitor that can block YAP1/TAZ signaling in animals and exhibits antitumor activity. It is for research use only.
- Orally active GGTase-I inhibitor.
- Blocks YAP1/TAZ signaling in animals.
- Possesses antitumor activity.
- Inhibits the proliferation of HT-1080 and MDA-MB-231 cells with IC50 values of 0.038 and 0.564 μM, respectively, in vitro.
- Shows dose-dependent antitumor activity in HT-1080 fibrosarcoma and MDA-MB-231 triple-negative breast cancer xenotransplantation mouse models in vivo.
Medchemexpress LLC Bay-593 | 2413020-56-9 | 99.9% | 476.53 g/mol | C26H31F3N2O3 | 10 MG
BAY-593 is an orally active geranylgeranyltransferase-I (GGTase-I) inhibitor that blocks YAP1/TAZ signaling and demonstrates antitumor activity in animal models. It is used as a research probe to study Rho-GTPase prenylation, YAP1/TAZ-dependent pathways, and related cancer biology applications.
- Orally active GGTase-I inhibitor suitable for in vivo studies.
- Blocks YAP1/TAZ signaling in cells and animals.
- Demonstrates antitumor activity in animal models.
- High purity solid form for research applications.
- Available in small research pack sizes and as a DMSO solution for screening.
![eMolecules 686723-63-7 | 1,4-DIOXA-9-AZADISPIRO[4.2.4.2]TETRADECAN-10-ONE | AstaTech | MFCD24551463 | 211.261 | C11H17NO3 | 95.000 | O=C1CCC2(CCC3(CC2)OCCO3)N1 | 0.1g | 722706964](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502474462.JPG-250.jpg)
eMolecules 686723-63-7 | 1,4-DIOXA-9-AZADISPIRO[4.2.4.2]TETRADECAN-10-ONE | AstaTech | MFCD24551463 | 211.261 | C11H17NO3 | 95.000 | O=C1CCC2(CCC3(CC2)OCCO3)N1 | 0.1g | 722706964
1,4-DIOXA-9-AZADISPIRO[4.2.4.2]TETRADECAN-10-ONE | AstaTech | 686723-63-7 | MFCD24551463 | 211.261 | C11H17NO3 | 95.000 | O=C1CCC2(CCC3(CC2)OCCO3)N1 | 0.1g | 722706964
eMolecules 2316817-88-4 | Medchem Express | CB-6644 | 1mg | 495799917 | HY-114429 | 573.06 | C29H34ClFN4O5
ChemScene | Methyl 4-(aminomethyl)bicyclo[2.2.2]octane-1-carboxylate | 100mg | 714103470 | CS-0092260 | 54202-09-4 | MFCD20699126 | 197.278 | C11H19NO2
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Medchemexpress LLC Myrcene (β-Myrcene) | 123-35-3 | 136.23 | 5 G
Myrcene (β-Myrcene) is an aromatic compound that inhibits TNFα and NF-κB activity. It possesses anti-invasive action, inhibits the cell cycle, and induces apoptosis in cancer cells. Additionally, Myrcene demonstrates strong blood protection effects, anti-inflammation, and anti-inflammatory activity.
- Inhibits TNFα and NF-κB activity
- Possesses anti-invasive properties
- Inhibits the cell cycle
- Induces apoptosis in cancer cells
- Demonstrates strong blood protection effects
- Anti-inflammation and anti-inflammatory activities
eMolecules 75-11-6 | Diiodomethane | Oakwood Chemical | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 500g | 537691337
Diiodomethane | Oakwood Chemical | 75-11-6 | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 500g | 537691337
eMolecules 75-11-6 | Diiodomethane | Combi-Blocks | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 100g | 117543611
Diiodomethane | Combi-Blocks | 75-11-6 | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 100g | 117543611
eMolecules 75-11-6 | Diiodomethane | Combi-Blocks | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 25g | 117543610
Diiodomethane | Combi-Blocks | 75-11-6 | MFCD00001079 | 267.836 | CH2I2 | 98.000 | ICI | 25g | 117543610
Sigma Aldrich Fine Chemicals Biosciences Dichloromethane biotech. g1L
DICHLOROMETHANE Dichloromethane biotech. g1L
![eMolecules 19718-88-8 | Ambeed | 14-Diazaspiro[4.5]decan-2-one | 100mg | 627733795 | A661361 | MFCD14584836 | 154.213 | C8H14N2O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502483738.JPG-250.jpg)
eMolecules 19718-88-8 | Ambeed | 14-Diazaspiro[4.5]decan-2-one | 100mg | 627733795 | A661361 | MFCD14584836 | 154.213 | C8H14N2O
Medchem Express | Cytidine 5-diphosphate (trisodium salt) | 5mg | 572597124 | HY-W008915 | 34393-59-4 | 469.122 | C9H12N3Na3O11P2
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