Aryl iodides
Medchemexpress LLC 5-Iodo-A-85380 dihyd 5mg | 1217837-17-6 | 5MG
5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR 5-Iodo-A-85380 dihydrochloride binds to 4 2 nAChRs in rat and human brain with Kds of 12 and 14 pM respectively[1
Medchemexpress LLC 5-iodo-A-85380 dihydrochloride | 1217837-17-6 | 99.0% | 363.02 | C9H13Cl2IN2O | 100 MG
5-Iodo-A-85380 dihydrochloride is a high-affinity, selective ligand for neuronal nicotinic acetylcholine receptors, with pronounced activity at the α4β2 subtype. Supplied as the dihydrochloride salt, it is intended for receptor binding, pharmacological profiling, and preclinical research applications. Reported binding affinities are 12 pM (rat) and 14 pM (human).
- High affinity for α4β2 nAChR (Kd 12 pM rat, 14 pM human).
- Provided as a dihydrochloride salt for stability in assays.
- Purity approximately 99.0% (HPLC).
- Molecular weight 363.02 and formula C9H13Cl2IN2O.
- Intended for receptor binding and pharmacological characterization in preclinical studies.
Medchemexpress LLC 5-iodo-A-85380 dihydrochloride hydrate | 1217837-17-6 | MFCD20488048 | 99.0% | 363.02 g/mol | C9H13Cl2IN2O | 50 MG
5-Iodo-A-85380 dihydrochloride is a research-grade, high-affinity ligand selective for α4β2 nicotinic acetylcholine receptors. Supplied as the dihydrochloride hydrate salt, it is intended for in vitro receptor binding and pharmacology studies where subtype-selective binding is required.
- Selective ligand for α4β2 and α6β2 nicotinic acetylcholine receptors.
- Very high binding affinity with reported Kd values of 12 pM (rat) and 14 pM (human).
- Supplied as the dihydrochloride hydrate salt for improved handling and stability.
- High purity (98.97%) suitable for biochemical assays.
- Molecular weight 363.02 g/mol; appropriate for molarity calculations in assays.
Medchemexpress LLC (S)-3-(azetidin-2-ylmethoxy)-5-iodopyridine dihydrochloride | 1217837-17-6 | 99.0% | 363.02 | C9H13Cl2IN2O | 10 MG
5-Iodo-A-85380 dihydrochloride is an iodinated, high-affinity ligand selective for neuronal nicotinic acetylcholine receptors (nAChRs), with potent binding at the α4β2 subtype. It is supplied for research applications in receptor binding and pharmacology, and has reported Kd values of ~12 pM (rat) and ~14 pM (human).
- High affinity for α4β2 nAChR enabling sensitive binding assays.
- Demonstrated selectivity for neuronal nicotinic receptor subtypes.
- High reported purity for reliable experimental results.
- Solid form with defined storage recommendations to preserve stability.
- Suitable for in vitro pharmacology and receptor characterization studies.
Medchemexpress LLC (S)-3-(azetidin-2-ylmethoxy)-5-iodopyridine dihydrochloride | 1217837-17-6 | MFCD03791315 | 99.0% | 363.02 g·mol⁻1 | C9H13Cl2IN2O | 25 MG
5-Iodo-A-85380 dihydrochloride is a high-affinity, small-molecule ligand and agonist for neuronal nicotinic acetylcholine receptors, with strong selectivity for the α4β2 subtype. It is supplied as the dihydrochloride salt for research use only and has a reported binding Kd of ≈12-14 pM.
- High affinity for α4β2 nicotinic acetylcholine receptors (Kd ≈12-14 pM).
- Selective agonist activity at α4β2 and α6β2 receptor subtypes.
- Supplied as the dihydrochloride salt for improved stability and handling.
- High purity suitable for research use (≈99.0%).
- Available in small-scale pack sizes for laboratory studies.