Indanes
![1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (ca. 50% in Diethyl Phthalate), TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-1222-05-5.jpg-250.jpg)
1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (ca. 50% in Diethyl Phthalate), TCI America™
CAS: 1222-05-5 Molecular Formula: C18H26O Molecular Weight (g/mol): 258.405 MDL Number: MFCD00217003 InChI Key: ONKNPOPIGWHAQC-UHFFFAOYSA-N PubChem CID: 91497 ChEBI: CHEBI:83784 IUPAC Name: 4,6,6,7,8,8-hexamethyl-1,3,4,7-tetrahydrocyclopenta[g]isochromene SMILES: CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C
Medchemexpress LLC HY-B0325 50mg Medchemexpress, Phenindione CAS:83-12-5 Purity:>98%
Medchemexpress, HY-B0325 50mg Phenindione CAS:83-12-5 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-11013 5mg Medchemexpress, ZSET1446 CAS:887603-94-3 Purity:>98%
Medchemexpress, HY-11013 5mg ZSET1446 CAS:887603-94-3 ZSET1446 is a novel cognitive enhancer that significantly improves learning deficits in various types of Alzheimer disease (AD) models. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-103371 100mg Medchemexpress, DCPIB CAS:82749-70-0 Purity:>98%
Medchemexpress, HY-103371 100mg DCPIB CAS:82749-70-0 DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC), voltage-dependently activates potassium channels TREK1 and TRAAK, inhibits TRESK, TASK1 and TASK3 (IC50s, 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM in CPAE cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-103371 5mg Medchemexpress, DCPIB CAS:82749-70-0 Purity:>98%
Medchemexpress, HY-103371 5mg DCPIB CAS:82749-70-0 DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels ( VRAC ), voltage-dependently activates potassium channels TREK1 and TRAAK, inhibits TRESK, TASK1 and TASK3 ( IC 50 s, 0.14, 0.95, 50.72 μM, respectively) [1] . DCPIB is also a selective blocker of swelling-induced chloride current ( I Cl,swell ), with an IC 50 of 4.1 μM in CPAE cells [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15105 5mg Medchemexpress, SB-423562 CAS:351490-27-2 Purity:>98%
Medchemexpress, HY-15105 5mg SB-423562 CAS:351490-27-2 SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-124625 5mg Medchemexpress, BI-4464 CAS:1227948-02-8 Purity:>98%
Medchemexpress, HY-124625 5mg BI-4464 CAS:1227948-02-8 BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK , with an IC 50 of 17 nM. A PTK2 ligand for PROTAC [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-12815A 50mg Medchemexpress, MCC950 (sodium) CAS:256373-96-3 Purity:>98%
Medchemexpress, HY-12815A 50mg MCC950 (sodium) CAS:256373-96-3 MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-14605 50mg Medchemexpress, Rasagiline (mesylate) CAS:161735-79-1 Purity:>98%
Medchemexpress, HY-14605 50mg Rasagiline (mesylate) CAS:161735-79-1 Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-13951 10mg Medchemexpress, ICI 118,551 (hydrochloride) CAS:72795-01-8 Purity:>98%
Medchemexpress, HY-13951 10mg ICI 118,551 (hydrochloride) CAS:72795-01-8 ICI 118,551 (hydrochloride) is a highly selective β2 adrenergic receptor antagonist, with Kis of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC GDC-0879(Synonyms: AR-00341677, GDC0879, GDC 0879, G-0879, G0879), 5mg, CAS: 905281-76-7.
GDC-0879 (CAS 905281-76-7) is a selective inhibitor of B-Raf kinase targeting the Raf/MEK/ERK signaling cascade implicated in tumorigenesis It specifically inhibits B-Raf harboring the V600E mutation demonstrating IC50 values of 0 13 nM against purified mutant B-Raf and 63 nM for phosphorylated ERK in MALME-3M cells In vitro assays using V600E mutant cell lines (A375 melanoma Colo205 colorectal cancer) illustrate the compound s selectivity towards B-Raf and related C-Raf kinases In mouse xenografts expressing human BRAFV600E tumors GDC-0879 treatment results in sustained ( 90%) inhibition of ERK phosphorylation and reduced tumor progression highlighting its research value in oncology studies involving Raf pathway modulation
Apexbio Technology LLC Ramelteon(Synonyms: Rozerem, TAK-375, Ramelteon, Melatonin receptor agonist, MT1/MT2 agonist), 5mg, CAS: 196597-26-9.
Ramelteon (CAS 196597-26-9) is a potent orally active agonist selective for MT1 and MT2 melatonin receptors Structurally characterized by its S-enantiomer and ether functional group ramelteon exhibits high binding affinity toward MT1 and MT2 receptors with reported Ki values of 14 pM and 112 pM respectively whereas affinity for the MT3 receptor is considerably lower (Ki 2650 nM) By activating MT1 and MT2 receptors ramelteon suppresses cAMP production in human cells expressing these receptors with IC50 values of 21 2 pM/L (MT1) and 53 4 pM/L (MT2) Given its receptor selectivity and minimal side-effect profile ramelteon is frequently utilized in research investigating circadian rhythms and sleep disorders
Apexbio Technology LLC MCC950 sodium(Synonyms: CP-456773 sodium, CRID3 sodium, MCC-950 sodium, MCC950 sodium salt), 10mg, CAS: 256373-96-3.
MCC950 sodium (CAS 256373-96-3) is a selective small-molecule inhibitor targeting the NOD-like receptor family protein 3 (NLRP3) inflammasome MCC950 sodium inhibits NLRP3 activation in murine bone marrow-derived macrophages (BMDMs) with an IC50 of 7 5 nM and demonstrates comparable selectivity and potency in human monocyte-derived macrophages (HMDMs) It specifically blocks both canonical and noncanonical activation pathways without affecting other inflammasomes such as AIM2 NLRC4 and NLRP1 Due to its selectivity MCC950 sodium is valuable in investigating NLRP3-associated inflammatory and autoimmune conditions
Sigma Aldrich 5-Aminoindan
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 3-(Benzyloxy)propanenitrile
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
- 1
- 2