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Filtered Search Results
Medchemexpress LLC BI-765423 25mg | 25mg
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BI-765423 is a human monoclonal antibody (mAb) targeting IL-11 BI-765423 can be used in fibrotic diseases research[1]
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Medchemexpress LLC Mocravimod hydrochloride | 509088-69-1 | 99.99% | 480.45 | 1 ML
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Mocravimod hydrochloride is an orally active sphingosine-1-phosphate receptor (S1PR) modulator. It works by blocking the signal required by T cells to egress from lymph nodes and other lymphoid organs, preferentially binding to S1PR1 over S1PR2 and S1PR3 in cardiomyocytes. This compound retains T cell effector function and is suitable for various research applications.
- Significantly lowers the concentration of reactive oxygen species (ROS).
- Prevents mitochondrial permeability transition pore opening.
- Boosts mitochondrial membrane potential (MMP).
- Increases phosphorylation of AKT, EKR, GSK-3β, JAK2, and STAT3.
- Retains T cell effector function.
- Used for the study of acute myelogenous leukemia, diabetes, and Myocardial Ischemia-Reperfusion Injury (MIRI).
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eMolecules 1245816-22-1 | 7-Tributylstannyl[1,2,4]triazolo[1,5-a]pyridine | Synthonix - Stock | MFCD17015011 | 408.177 | C18H31N3Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccn2ncnc2c1 | 250mg | 525924365
7-Tributylstannyl[1,2,4]triazolo[1,5-a]pyridine | Synthonix - Stock | 1245816-22-1 | MFCD17015011 | 408.177 | C18H31N3Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccn2ncnc2c1 | 250mg | 525924365
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eMolecules 917382-51-5 | 4-(Ethylsulfanyl)phenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock241.430 | C8H9BrMgS | 97.000 | [Br-].CCSc1ccc([Mg+])cc1 | 50ml | 437237200
4-(Ethylsulfanyl)phenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 917382-51-5241.430 | C8H9BrMgS | 97.000 | [Br-].CCSc1ccc([Mg+])cc1 | 50ml | 437237200
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eMolecules 1161737-33-2 | 6-Cyclopropyl-3(2H)-pyridazinone | ChemScene | MFCD16871334 | 136.154 | C7H8N2O | 97.000 | O=c1ccc(n[nH]1)C1CC1 | 1g | 569147517
6-Cyclopropyl-3(2H)-pyridazinone | ChemScene | 1161737-33-2 | MFCD16871334 | 136.154 | C7H8N2O | 97.000 | O=c1ccc(n[nH]1)C1CC1 | 1g | 569147517
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eMolecules 606-40-6 | 2-Chloro-1-naphthol | Apollo Scientific | MFCD18415868 | 178.620 | C10H7ClO | 97.000 | Oc1c(Cl)ccc2ccccc12 | 1g | 562426273
2-Chloro-1-naphthol | Apollo Scientific | 606-40-6 | MFCD18415868 | 178.620 | C10H7ClO | 97.000 | Oc1c(Cl)ccc2ccccc12 | 1g | 562426273
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eMolecules 325486-45-1 | tert-Butyl 4-oxo-3,4-dihydropyridine-1(2H)-carboxylate | ChemScene | MFCD08437478 | 197.234 | C10H15NO3 | 95.000 | CC(C)(C)OC(=O)N1CCC(=O)C=C1 | 1g | 572305464
tert-Butyl 4-oxo-3,4-dihydropyridine-1(2H)-carboxylate | ChemScene | 325486-45-1 | MFCD08437478 | 197.234 | C10H15NO3 | 95.000 | CC(C)(C)OC(=O)N1CCC(=O)C=C1 | 1g | 572305464
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eMolecules 308795-93-9 | 4-Methyl-2-pyridylzinc bromide, 0.50 M in THF | Synthonix237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1ccnc([Zn+])c1 | 25ml | 627353704
4-Methyl-2-pyridylzinc bromide, 0.50 M in THF | Synthonix | 308795-93-9237.410 | C6H6BrNZn | 0.000 | [Br-].Cc1ccnc([Zn+])c1 | 25ml | 627353704
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Medchemexpress LLC Quinacrine hydrochloride hydrate | 6151-30-0 | 98.2% | 508.91 | 100 MG
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Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent with anticancer effects both in vitro and in vivo. It suppresses NF-κB and activates p53 signaling, which results in the induction of apoptosis.
- Antimalarial agent
- Possesses anticancer effects both in vitro and in vivo
- Suppresses NF-κB and activates p53 signaling
- Induces apoptosis
- Inhibits growth and induces apoptosis in SGC-7901 cells
- Increases proapoptotic proteins (cytochrome c, Bax, p53) and decreases antiapoptotic protein (Bcl-2)
- Suppresses circulating blast cells and increases survival time in an AML-PS model
- Does not decrease body weight in treated animals
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eMolecules 1075198-30-9 | (1-Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino-carbenium hexafluorophosphate | Oakwood Chemicals | MFCD11975052 | 428.272 | C12H19F6N4O4P | 98.000 | F[P-](F)(F)(F)(F)F.CCOC(=O)C(=N/OC(N1CCOCC1)=[N+](C)C)\C#N | 5g | 480131312
(1-Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino-carbenium hexafluorophosphate | Oakwood Chemicals | 1075198-30-9 | MFCD11975052 | 428.272 | C12H19F6N4O4P | 98.000 | F[P-](F)(F)(F)(F)F.CCOC(=O)C(=N/OC(N1CCOCC1)=[N+](C)C)\C#N | 5g | 480131312
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 13132-23-5 | 2,2-Dimethylpropylmagnesium chloride, 1.0 M in THF | Synthonix | MFCD00061550 | 130.900 | C5H11ClMg | 0.000 | [Cl-].CC(C)(C)C[Mg+] | 25ml | 804019715
2,2-Dimethylpropylmagnesium chloride, 1.0 M in THF | Synthonix | 13132-23-5 | MFCD00061550 | 130.900 | C5H11ClMg | 0.000 | [Cl-].CC(C)(C)C[Mg+] | 25ml | 804019715
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eMolecules [3-Fluoro-4-(trifluoromethoxy)phenyl]zinc bromide, 0.5 M in THF | Synthonix |324.380 | C7H3BrF4OZn | 0.000 | [Br-].Fc1cc([Zn+])ccc1OC(F)(F)F | 50ml | 812584979
[3-Fluoro-4-(trifluoromethoxy)phenyl]zinc bromide, 0.5 M in THF | Synthonix |324.380 | C7H3BrF4OZn | 0.000 | [Br-].Fc1cc([Zn+])ccc1OC(F)(F)F | 50ml | 812584979
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Medchemexpress LLC Aceclidine hydrochloride | 6109-70-2 | MFCD00468105 | 98.0% | 205.68 | 1 G
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Aceclidine (Quinuclidin-3-yl acetate) hydrochloride is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC50: 40 μM). It is also a cycloplegic agent, a surfactant, a tonicity adjustor, and optionally a viscosity enhancer and an antioxidant. It has potential for research into various disorders including refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia.
- Modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC50: 40 μM)
- Cycloplegic agent
- Surfactant
- Tonicity adjustor
- Optionally a viscosity enhancer and an antioxidant
- Potential for research of disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 7565-59-5 | tert-Butylzinc bromide, 0.50 M in THF | Synthonix | MFCD00671989 | 202.400 | C4H9BrZn | 0.000 | [Br-].CC(C)(C)[Zn+] | 100ml | 627353801
tert-Butylzinc bromide, 0.50 M in THF | Synthonix | 7565-59-5 | MFCD00671989 | 202.400 | C4H9BrZn | 0.000 | [Br-].CC(C)(C)[Zn+] | 100ml | 627353801
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 308796-27-2 | 4-(Methylthio)phenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01863641 | 315.480 | C7H7ISZn | 95.000 | [I-].CSc1ccc([Zn+])cc1 | 50ml | 721997567
4-(Methylthio)phenylzinc iodide, 0.50 M in THF | Synthonix | 308796-27-2 | MFCD01863641 | 315.480 | C7H7ISZn | 95.000 | [I-].CSc1ccc([Zn+])cc1 | 50ml | 721997567
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