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Filtered Search Results
eMolecules 307496-28-2 | 3-Fluorophenylzinc iodide, 0.50 M in THF | Synthonix | MFCD01311395 | 287.380 | C6H4FIZn | 0.000 | [I-].Fc1cccc([Zn+])c1 | 50ml | 532652841
3-Fluorophenylzinc iodide, 0.50 M in THF | Synthonix | 307496-28-2 | MFCD01311395 | 287.380 | C6H4FIZn | 0.000 | [I-].Fc1cccc([Zn+])c1 | 50ml | 532652841
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 352530-43-9 | 2,5-Dichlorophenylzinc iodide, 0.50 M in THF | Synthonix | MFCD02260175 | 338.270 | C6H3Cl2IZn | 0.000 | [I-].Clc1ccc(Cl)c([Zn+])c1 | 25ml | 627353601
2,5-Dichlorophenylzinc iodide, 0.50 M in THF | Synthonix | 352530-43-9 | MFCD02260175 | 338.270 | C6H3Cl2IZn | 0.000 | [I-].Clc1ccc(Cl)c([Zn+])c1 | 25ml | 627353601
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eMolecules 66-71-7 | o-Phenanthroline | ChemScene | MFCD00011678 | 180.210 | C12H8N2 | 98.000 | c1cnc2c(c1)ccc1cccnc21 | 25g | 346751520
o-Phenanthroline | ChemScene | 66-71-7 | MFCD00011678 | 180.210 | C12H8N2 | 98.000 | c1cnc2c(c1)ccc1cccnc21 | 25g | 346751520
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 312693-14-4 | 1-Ethylbutylzinc bromide, 0.50 M in THF | Synthonix230.450 | C6H13BrZn | 0.000 | [Br-].CCCC([Zn+])CC | 50ml | 532652797
1-Ethylbutylzinc bromide, 0.50 M in THF | Synthonix | 312693-14-4230.450 | C6H13BrZn | 0.000 | [Br-].CCCC([Zn+])CC | 50ml | 532652797
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 2-(naphthalen-2-yl)acetonitrile | 7498-57-9 | MFCD00004122 | 100.0% | 167.21 g/mol | C12H9N | 500 G
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2-(Naphthalen-2-yl)acetonitrile is a chemical intermediate used in the synthesis of active pharmaceutical compounds and research-stage derivatives. It has molecular formula C12H9N and a molecular weight of 167.21 g/mol. The product is supplied in laboratory and bulk pack sizes and is accompanied by a product datasheet and safety data sheet for research use only.
- Drug intermediate for synthesis of active pharmaceutical compounds.
- Molecular formula C12H9N; molecular weight 167.21 g/mol.
- High reported purity (99.96%).
- Available in laboratory and bulk pack sizes, including 500 g.
- Supplied with accompanying datasheet and safety data sheet.
- Intended for research use; not for human or veterinary use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 131554-33-1 | 2-Benzothiazolylmagnesium bromide, 0.50 M in THF | Synthonix238.390 | C7H4BrMgNS | 0.000 | [Br-].[Mg+]c1nc2ccccc2s1 | 50ml | 702445851
2-Benzothiazolylmagnesium bromide, 0.50 M in THF | Synthonix | 131554-33-1238.390 | C7H4BrMgNS | 0.000 | [Br-].[Mg+]c1nc2ccccc2s1 | 50ml | 702445851
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Medchemexpress LLC BI-3231 | 2894848-07-6 | 99.8% | 380.37 | 50 MG
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BI-3231 is a potent and selective chemical probe that inhibits hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), with IC50 values of 1 nM for hHSD17B13 and 13 nM for mHSD17B13. It is being researched for its potential in treating nonalcoholic steatohepatitis (NASH) and other liver diseases.
- Potent and selective hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) inhibitor
- Demonstrates high metabolic stability in liver microsomes
- Moderate metabolic stability in hepatocytes
- Significant hepatic exposure maintained over 48 hours
- Potential for research into nonalcoholic steatohepatitis (NASH) and other liver diseases
- Powder storage: -20°C for 3 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Solubility in DMSO: 125 mg/mL (328.63 mM)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 131379-16-3 | 4-(Ethoxycarbonyl)phenylzinc iodide, 0.50 M in THF | Synthonix | MFCD00671982 | 341.450 | C9H9IO2Zn | 0.000 | [I-].CCOC(=O)c1ccc([Zn+])cc1 | 100ml | 532652818
4-(Ethoxycarbonyl)phenylzinc iodide, 0.50 M in THF | Synthonix | 131379-16-3 | MFCD00671982 | 341.450 | C9H9IO2Zn | 0.000 | [I-].CCOC(=O)c1ccc([Zn+])cc1 | 100ml | 532652818
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 194366-72-8 | 1-Ethoxyvinylzinc chloride, 0.25M in THF/Pentane | Synthonix - Stock171.930 | C4H7ClOZn | 95.000 | [Cl-].CCOC([Zn+])=C | 50ml | 363363216
1-Ethoxyvinylzinc chloride, 0.25M in THF/Pentane | Synthonix - Stock | 194366-72-8171.930 | C4H7ClOZn | 95.000 | [Cl-].CCOC([Zn+])=C | 50ml | 363363216
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC BLU-945 | 2660250-10-0 | 99.4% | C28H37FN6O3S | 100 MG
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BLU-945 is a potent, highly selective, reversible, and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It effectively inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation, making it suitable for research into lung cancer, including non-small cell lung cancer (NSCLC).
- Potent, highly selective, reversible, and orally active EGFR tyrosine kinase inhibitor.
- Effectively inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation.
- Used for research of lung cancer, including non-small cell lung cancer (NSCLC).
- Exhibits inhibitory activity against EGFRm/T790M double and EGFRm/T790M/C797S triple mutants.
- Demonstrates potent, robust EGFR pathway inhibition and anti-tumor activity in Osimertinib-resistant models.
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eMolecules 2135683-36-0 | (1-tert-Butoxycarbonyl-3-piperidyl)methylzinc iodide, 0.5M in THF | Synthonix - Stock | MFCD31536795 | 390.570 | C11H20INO2Zn | 0.000 | [I-].CC(C)(C)OC(=O)N1CCCC(C[Zn+])C1 | 50ml | 353483964
(1-tert-Butoxycarbonyl-3-piperidyl)methylzinc iodide, 0.5M in THF | Synthonix - Stock | 2135683-36-0 | MFCD31536795 | 390.570 | C11H20INO2Zn | 0.000 | [I-].CC(C)(C)OC(=O)N1CCCC(C[Zn+])C1 | 50ml | 353483964
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC BI-2865 | 2937327-93-8 | C23H27N7O2S | 1 MG
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BI-2865 is a non-covalent pan-KRAS inhibitor. It binds to wild-type (WT) and several mutant KRAS forms, including G12C, G12D, G12V, and G13D, with KDs ranging from 4.3 to 32 nM. This compound effectively inhibits the proliferation of G12C, G12D, or G12V mutant KRAS expressing BaF3 cells, showing a mean IC50 of approximately 140 nM.
- Binds to multiple KRAS mutants (WT, G12C, G12D, G12V, G13D)
- Inhibits proliferation of KRAS mutant expressing BaF3 cells
- Derivative with a prolinol substituent and a pyrimidine linker
- Exhibits direct ionic interaction with E62 and a water-mediated hydrogen bond network
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC BI-9787 | 3043939-18-7 | 99.5% | 489.58 | 5 MG
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BI-9787 is a zwitterionic inhibitor for ketohexokinase (KHK), demonstrating IC50 values of 12 nM for hKHK-A and 12.8 nM for hKHK-C. It shows good metabolic stability in rat hepatocytes and favorable pharmacokinetic characteristics in rats. This product was designed by Boehringer Ingelheim and is available free of charge through their open innovation portal opnMe.com, alongside its negative control. It is intended for research use only and not for sale to patients.
- Zwitterionic inhibitor for ketohexokinase (KHK)
- IC50 of 12 nM for hKHK-A and 12.8 nM for hKHK-C
- Exhibits good metabolic stability in rat hepatocyte
- Shows good pharmacokinetic characteristics in rats
- Intended for research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 13291-18-4 | Isopropenylmagnesium bromide, 0.50 M in THF | Synthonix | MFCD00192240 | 145.282 | C3H5BrMg | 0.000 | [Br-].CC([Mg+])=C | 50ml | 649431319
Isopropenylmagnesium bromide, 0.50 M in THF | Synthonix | 13291-18-4 | MFCD00192240 | 145.282 | C3H5BrMg | 0.000 | [Br-].CC([Mg+])=C | 50ml | 649431319
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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TARGETMOL CHEMICALS INC BI-3812 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BI-3812 is an inhibitor of BCL6. Which inhibiting the BTB domain of BCL6 (IC50 3 nM). BI-3812 also has antitumor activity. purity: 99%
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