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Filtered Search Results
Medchemexpress LLC Migalastat (hydrochloride) | 75172-81-5 | ≥99.0% | 199.63 | 10MM/1ML
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Migalastat hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. It functions by binding to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, it enables the mutant α-galactosidase A to exhibit biological activity.
- Binds to the active site of certain unstable mutant forms of α-galactosidase A
- Facilitates transport to the lysosome
- Enables mutant α-galactosidase A to exhibit biological activity
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eMolecules 105494-69-7 | 1-Methyl-2-(tributylstannyl)imidazole | Synthonix - Stock | MFCD01319030 | 371.156 | C16H32N2Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1nccn1C | 1g | 525920332
1-Methyl-2-(tributylstannyl)imidazole | Synthonix - Stock | 105494-69-7 | MFCD01319030 | 371.156 | C16H32N2Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1nccn1C | 1g | 525920332
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Medchemexpress LLC Clobutinol hydrochloride | 1215-83-4 | 99.86% | 292.24 | 100 MG
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Clobutinol hydrochloride is a compound with anti-tussive effects. It influences heart rate and blood pressure, making it suitable for cough-related research.
- Has anti-tussive effects.
- Influences heart rate and blood pressure.
- Used in cough related research.
- Functions as a potassium channel inhibitor.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1245816-06-1 | 2-Fluoro-4-methyl-5-(tributylstannyl)pyridine | Synthonix - Stock | MFCD12827558 | 400.169 | C18H32FNSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1cnc(F)cc1C | 1g | 525917649
2-Fluoro-4-methyl-5-(tributylstannyl)pyridine | Synthonix - Stock | 1245816-06-1 | MFCD12827558 | 400.169 | C18H32FNSn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1cnc(F)cc1C | 1g | 525917649
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eMolecules 36229-42-2 | 3-Chlorophenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | MFCD00672003 | 215.760 | C6H4BrClMg | 0.000 | [Br-].[Mg+]c1cccc(Cl)c1 | 500ml | 437237034
3-Chlorophenylmagnesium bromide, 0.5M in THF | Synthonix - Stock | 36229-42-2 | MFCD00672003 | 215.760 | C6H4BrClMg | 0.000 | [Br-].[Mg+]c1cccc(Cl)c1 | 500ml | 437237034
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eMolecules 56-24-6 | TRIMETHYLSTANNANOL | AstaTech182.838 | C3H12OSn | 98.000 | O.C[SnH](C)C | 1g | 718346838
TRIMETHYLSTANNANOL | AstaTech | 56-24-6182.838 | C3H12OSn | 98.000 | O.C[SnH](C)C | 1g | 718346838
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Medchemexpress LLC Diphenidol hydrochloride | 3254-89-5 | MFCD00151479 | 99.1% | C21H28ClNO | 1 G
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Diphenidol hydrochloride is a non-selective muscarinic M1-M4 receptor antagonist with anti-arrhythmic activity. It is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells. It can be used in the study of antivertigo and antinausea.
- Acts as a non-selective muscarinic M1-M4 receptor antagonist
- Exhibits anti-arrhythmic activity
- Functions as a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells
- Inhibits sodium currents and can produce spinal anesthesia
- Shown to reduce neuropathic pain and TNF-α overexpression in rat models
- Demonstrates an inhibitory effect on exercise and morphine-induced vomiting in pica rats
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eMolecules 1032315-16-4 | 7-Trimethylstannylisoquinoline | Synthonix - Stock | MFCD22199151 | 291.969 | C12H15NSn | 97.000 | C[Sn](C)(C)c1ccc2ccncc2c1 | 1g | 525924353
7-Trimethylstannylisoquinoline | Synthonix - Stock | 1032315-16-4 | MFCD22199151 | 291.969 | C12H15NSn | 97.000 | C[Sn](C)(C)c1ccc2ccncc2c1 | 1g | 525924353
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Medchemexpress LLC 1-[(3,5-dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide | 2227549-00-8 | >95.0% | 445.34 g·mol^-1 | C19H19Cl2FN2O3S | 100MG
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BI-01383298 is a small-molecule chemical probe that selectively inhibits the sodium-coupled citrate transporter SLC13A5 (NaCT). Developed by Boehringer Ingelheim and distributed by research suppliers, it is used in cellular studies to probe NaCT function. The compound is provided for laboratory research use only and is characterized by a defined molecular formula and molecular weight.
- Potent inhibitor of SLC13A5 with reported cellular IC50 values in the low nanomolar range (examples: 56 nM and 24 nM).
- High selectivity over related transporters, reported greater than 1,000-fold in some assays.
- Molecular weight approximately 445.3 g·mol^-1 and formula C19H19Cl2FN2O3S.
- Typical supplier-reported purity ≥95%, with some distributors listing higher specifications.
- Available as solid quantities and as a 10 mM solution in DMSO for cell-based assays.
- For research use only; not for human or clinical use.
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eMolecules 479094-62-7 | Di-tert-butylmethylphosphine tetrafluoroborate | Synthonix | MFCD03840579 | 248.050 | C9H22BF4P | 95.000 | F[B-](F)(F)F.C[PH+](C(C)(C)C)C(C)(C)C | 10g | 719909080
Di-tert-butylmethylphosphine tetrafluoroborate | Synthonix | 479094-62-7 | MFCD03840579 | 248.050 | C9H22BF4P | 95.000 | F[B-](F)(F)F.C[PH+](C(C)(C)C)C(C)(C)C | 10g | 719909080
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Medchemexpress LLC 6-(5-methoxymethyl-pyridin-3-yl)-3,4-dihydro-2H-naphthyridine-1-carboxylic acid amide | 1633009-87-6 | 99.2% | 298.34 | C16H18N4O2 | 25 MG
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The compound is a small-molecule, highly selective aldosterone synthase (CYP11B2) inhibitor with nanomolar potency, used in biochemical and pharmacological research to probe aldosterone synthesis and CYP11B2-mediated pathways. It exhibits reported IC50 values of 2.1 nM for CYP11B2 and 310 nM for CYP11B1, and is supplied as a high-purity solid for laboratory studies.
- Highly selective aldosterone synthase inhibitor with nanomolar potency (CYP11B2 IC50 ≈ 2.1 nM).
- Reduced off-target activity against CYP11B1 (IC50 ≈ 310 nM).
- Molecular formula C16H18N4O2; molecular weight 298.34 g/mol.
- Purity 99.2% as reported by supplier.
- Supplied as a small solid quantity suitable for in vitro and in vivo research (e.g., 25 mg).
- Characterized in peer-reviewed pharmacology studies for selectivity and pharmacodynamics.
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eMolecules Synthonix [4-[tert-Butyl(dimethyl)silyl]oxybutyl]magnesium bromide 0.50 M in THF 25ml 795399106 B81015 152841-72-0 [null] 291.587 C10H23BrMgOSi
Synthonix [4-[tert-Butyl(dimethyl)silyl]oxybutyl]magnesium bromide 0.50 M in THF 25ml 795399106 B81015 152841-72-0 [null] 291.587 C10H23BrMgOSi
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Medchemexpress LLC Vardenafil (hydrochloride trihydrate) | 330808-88-3 | 99.7% | 25 MG
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Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. It competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis, thereby increasing cGMP levels. This compound can be used for research related to erectile dysfunction, hepatitis, and diabetes.
- Selective and orally active inhibitor of phosphodiesterase-5 (PDE5).
- Inhibits PDE1 and PDE6 with IC50s of 180 nM and 11 nM.
- IC50s are >1000 nM for PDE3 and PDE4.
- Increases intracellular cGMP levels.
- Suitable for research of erectile dysfunction, hepatitis, and diabetes.
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eMolecules 208465-07-0 | 3,6-Dihydro-4-(tributylstannyl)-1(2H)-pyridine carboxylic acid t-butyl ester | Synthonix - Stock | MFCD18325165 | 472.301 | C22H43NO2Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)C1=CCN(CC1)C(=O)OC(C)(C)C | 1g | 525915735
3,6-Dihydro-4-(tributylstannyl)-1(2H)-pyridine carboxylic acid t-butyl ester | Synthonix - Stock | 208465-07-0 | MFCD18325165 | 472.301 | C22H43NO2Sn | 97.000 | CCCC[Sn](CCCC)(CCCC)C1=CCN(CC1)C(=O)OC(C)(C)C | 1g | 525915735
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eMolecules 395-47-1 | (2-(trifluoromethyl)phenyl)magnesium bromide, 0.50 M in THF | Synthonix | MFCD18253606 | 249.313 | C7H4BrF3Mg | 0.000 | [Br-].FC(F)(F)c1ccccc1[Mg+] | 100ml | 702445989
(2-(trifluoromethyl)phenyl)magnesium bromide, 0.50 M in THF | Synthonix | 395-47-1 | MFCD18253606 | 249.313 | C7H4BrF3Mg | 0.000 | [Br-].FC(F)(F)c1ccccc1[Mg+] | 100ml | 702445989
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