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Filtered Search Results
eMolecules 693-25-4 | Pentylmagnesium bromide, 1.0 M in THF | Synthonix175.352 | C5H11BrMg | 0.000 | [Br-].CCCCC[Mg+] | 100ml | 702445977
Pentylmagnesium bromide, 1.0 M in THF | Synthonix | 693-25-4175.352 | C5H11BrMg | 0.000 | [Br-].CCCCC[Mg+] | 100ml | 702445977
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Medchemexpress LLC Amorolfine (hydrochloride) | 78613-38-4 | 99.8% | 500 MG
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Amorolfine hydrochloride is a potent anti-fungal agent that inhibits ergosterol biosynthesis. It has potential for research on *Neoscytalidium dimidiatum* onychomycosis, exhibiting both fungistatic and fungicidal activity.
- Potent anti-fungal agent
- Inhibits ergosterol biosynthesis
- Exhibits fungistatic and fungicidal activity
- Available as a white to off-white solid
- Store at 4°C, sealed, away from moisture
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Medchemexpress LLC Phenformin hydrochloride | 834-28-6 | 99.6% | 241.72 | 5 G
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Phenformin hydrochloride is an anti-diabetic agent from the biguanide class that can activate AMPK activity. It is intended for research use only and is a white to off-white solid.
- Activates AMPK activity
- Solid appearance
- White to off-white color
- Store at 4°C under nitrogen, away from moisture
- Soluble in H2O and DMSO
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Medchemexpress LLC EGFR vIII Human Bi 20ug | 20ug
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The EGFRvIII protein is a transmembrane glycoprotein in the protein kinase superfamily that acts as a receptor for epidermal growth factor It acts on the cell surface binds to epidermal growth factor triggers receptor dimerization and tyrosine autophosphorylation and promotes cell proliferation EGFR vIII Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived EGFR vIII protein expressed by HEK293 with C-Avi C-His labeled tag
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eMolecules 121359-48-6 | 2-(Tributylstannyl)thiazole | Synthonix - Stock | MFCD01319057 | 374.170 | C15H29NSSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1nccs1 | 500mg | 525923778
2-(Tributylstannyl)thiazole | Synthonix - Stock | 121359-48-6 | MFCD01319057 | 374.170 | C15H29NSSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1nccs1 | 500mg | 525923778
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Medchemexpress LLC Cysteamine (hydrochloride) | 156-57-0 | 99.3% | C2H8ClNS | 25 MG
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Cysteamine hydrochloride is an orally active agent used for the treatment of nephropathic cystinosis and acts as an antioxidant. It is intended for research use only.
- Increases intracellular glutathione levels in cystinotic cells
- Counteracts increased rates of apoptosis in cystinotic cells
- Exhibits antioxidant properties
- Acts as an excellent scavenger of OH and HOCl
- Increases production of several heat shock proteins
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eMolecules 119277-44-0 | 3-Bromo-2-thienylmagnesium bromide, 0.25 M in 2-MeTHF | Synthonix266.230 | C4H2Br2MgS | 0.000 | [Br-].[Mg+]c1sccc1Br | 50ml | 702445854
3-Bromo-2-thienylmagnesium bromide, 0.25 M in 2-MeTHF | Synthonix | 119277-44-0266.230 | C4H2Br2MgS | 0.000 | [Br-].[Mg+]c1sccc1Br | 50ml | 702445854
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eMolecules 164014-94-2 | 2-Methoxy-6-(tributylstannyl)pyridine | Synthonix - Stock | MFCD09025803 | 398.178 | C18H33NOSn | 94.000 | CCCC[Sn](CCCC)(CCCC)c1cccc(OC)n1 | 5g | 525920490
2-Methoxy-6-(tributylstannyl)pyridine | Synthonix - Stock | 164014-94-2 | MFCD09025803 | 398.178 | C18H33NOSn | 94.000 | CCCC[Sn](CCCC)(CCCC)c1cccc(OC)n1 | 5g | 525920490
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eMolecules 674346-88-4 | 4-Fluorophenylzinc iodide, 0.50 M in THF | Synthonix287.380 | C6H4FIZn | 0.000 | [I-].Fc1ccc([Zn+])cc1 | 25ml | 627353650
4-Fluorophenylzinc iodide, 0.50 M in THF | Synthonix | 674346-88-4287.380 | C6H4FIZn | 0.000 | [I-].Fc1ccc([Zn+])cc1 | 25ml | 627353650
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eMolecules 1226769-58-9 | 6-Methoxypyridin-2-ylmagnesium bromide, 0.25 M in THF | Synthonix212.329 | C6H6BrMgNO | 0.000 | [Br-].COc1cccc([Mg+])n1 | 50ml | 702445946
6-Methoxypyridin-2-ylmagnesium bromide, 0.25 M in THF | Synthonix | 1226769-58-9212.329 | C6H6BrMgNO | 0.000 | [Br-].COc1cccc([Mg+])n1 | 50ml | 702445946
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Apexbio Technology LLC BI-847325 1207293-36-4 25mg
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BI-847325 (CAS 1207293-36-4) is a dual inhibitor targeting MEK1/2 and Aurora kinases with reported IC50 values of 25 nM and 4 nM against MEK1 and MEK2 and 3 nM 25 nM and 15 nM against Aurora A B and C respectively By inhibiting these kinases BI-847325 disrupts the MAPK/ERK and cell cycle signaling pathways that regulate cell proliferation and survival In cellular assays it demonstrates nanomolar EC50 values for inhibition of pERK and pHH3 in KRAS- and BRAF-mutant cancer cell lines and potently suppresses proliferation across a wide range of tumor cell models In xenograft studies it fully blocks tumor growth in BRAF- and KRAS-mutant cancer models This compound is utilized in research on kinase-targeted cancer therapies
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AdipoGen 3 4-Dihydroxy-L-phenylalanine
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Chemical. CAS 59-92-7. Formula C9H11NO4. MW 197.19. Synthetic. Metabolic precursor of the neurotransmitters dopamine, norepinephrine noradrenaline, and epinephrine adrenaline, which are collectively known as catecholamines. This amino acid is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase COMT. L-DOPA is capable of crossing the blood brain barrier where it is converted to dopamine. Formulations containing L-DOPA have been used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery. Mediates neurotrophic factor release by the brain and CNS. Used for the treatment of Parkinson’s disease and dopamine-responsive dystonia. In addition it is used, as a cell adhesion molecule in serum-free cultures of anchorage-dependent mammalian cells, to prevent surfaces from fouling by bonding antifouling polymers to a susceptible substrate or to stain melanocytes.
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eMolecules 1390658-33-9 | 2,3-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1cccc(C[Zn+])c1F | 25ml | 627353594
2,3-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix | 1390658-33-9272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1cccc(C[Zn+])c1F | 25ml | 627353594
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AdipoGen Naphthol AS-MX phosphate
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Chemical. CAS 1596-56-1. Formula C19H18NO5P. MW BD9837. Naphthol AS-MX Phosphate is a fluorogenic substrate for alkaline phosphatases. Naphthol AS-MX Phosphate is converted to naphthol AS-MX displaying excitation/emission spectra of 388/512nm. The fluorescence is a quantitative marker of acid and alkaline phosphatase activity. Acid and alkaline phosphatases are often used as clinical markers of disease, since the concentration of human acid and alkaline phosphatases undergo pronounced changes in particular diseases, resulting in unusually high or low concentrations. It is a histochemical substrate commonly used in conjunction with diazonium salts to form a specific azo dye for immunohistology, immunoblotting and dot blot applications.
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Medchemexpress LLC (±)-BI-D | 1416258-16-6 | 98.1% | 10 MG
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(±)-BI-D is an allosteric HIV integrase inhibitor used in research to study integrase function and antiviral activity. It binds the LEDGF/p75 binding site on integrase and has demonstrated inhibition of HIV-Luc infection in cellular assays.
- Potent ALLINI mechanism of action.
- Binds LEDGF/p75 integrase site to disrupt viral integration.
- Demonstrated cellular activity (reported IC50s: 0.16 μM and 2.9 μM).
- Available as solid and as a 10 mM solution in DMSO for assay setup flexibility.
- High purity and defined molecular weight and formula for reproducible studies.
- Intended for biochemical and cellular research use only; not for human use.
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